|
propene degradation
|
PWY-5534
|
2-(R)-hydroxypropyl-CoM dehydrogenase [XecD]4|2-oxopropyl-CoM reductase (carboxylating)|alkene monooxygenase [([AamA][AamE][AamB])2][AamF][(AamC)2][AamD]|2-(R)-hydroxypropyl-CoM dehydrogenase|2-(S)-hydroxypropyl-CoM dehydrogenase [XecE]2|2-hydroxypropyl-CoM lyase|alkene monooxygenase|2-oxopropyl-CoM reductase (carboxylating) [XecC]2|2-(S)-hydroxypropyl-CoM dehydrogenase
|
H2O|NADPH|(S)-1,2-epoxypropane|(R)-1,2-epoxypropane|acetoacetate|NADP+|2-oxopropyl-CoM|CO2|propene|2-(S)-hydroxypropyl-CoM|H+|NAD+|coenzyme M|NADH|oxygen|2-(R)-hydroxypropyl-CoM
|
2
|
|
rhamnogalacturonan type I degradation I (fungi)
|
PWY-6769
|
rhamnogalacturonan acetylesterase rha1|rhamnogalacturonan hydrolase|rhamnogalacturonan hydrolase rhgA|rhamnogalacturonan acetylesterase|rhamnogalacturonan galacturonohydrolase|rhamnogalacturonan endolyase|rhamnogalacturonan rhamnohydrolase
|
β-L-rhamnopyranose|β-D-galacturonate|H2O|acetate
|
2
|
|
sanguinarine and macarpine biosynthesis
|
PWY-5287
|
allocryptopine 6-hydroxylase / protopine-6-hydroxylase CYP82N2v2|(S)- cheilanthifoline synthase|(S)-stylopine synthase|(S)-nandinine synthase / stylopine synthase|dihydrochelirubine-12-hydroxylase|12-hydroxydihydrochelirubine-12-O-methyltransferase|sanguinarine reductase|(S)-cis-N-methylstylopine 14-hydroxylase/(S)-N-methylcanadine 14-monooxygenase|sanguinarine reductase SARED1|dihydrobenzophenanthridine oxidase|tetrahydroprotoberberine-cis-N-methyltransferase|(S)-cis-N-methylstylopine 14-hydroxylase/(S)-N-methylcanadine 14-hydroxylase|(S)-chelanthifoline synthase|10-hydroxydihydrosanguinarine-10-O-methyltransferase|allocryptopine 6-hydroxylase / protopine-6-hydroxylase|dihydrosanguinarine-10-hydroxylase|canadine N-methyltransferase / tetrahydroprotoberberine cis-N-methyltransferase|benzylisoquinoline synthase|tetrahydroprotoberberine synthase
|
S-adenosyl-L-methionine|NADPH|(S)-cis-N-methylstylopine|12-hydroxydihydrochelirubine|dihydrochelirubine|H2O|sanguinarine|6-hydroxyprotopine|NADP+|(S)-nandinine|oxygen|S-cheilanthifoline|S-adenosyl-L-homocysteine|(S)-reticuline|hydrogen peroxide|macarpine|dihydrosanguinarine|10-hydroxydihydrosanguinarine|dihydromacarpine|protopine|H+|chelirubine|(S)-scoulerine
|
2
|
|
serotonin and melatonin biosynthesis
|
PWY-6030
|
acetylserotonin O-methyltransferase|L-DOPA decarboxylase|tryptophan 5-hydroxylase 1|tryptophan hydroxylase 2|aromatic L-amino acid decarboxylase|serotonin N-acetyltransferase|aralkylamine N-acetyltransferase
|
S-adenosyl-L-methionine|acetyl-CoA|5-hydroxy-L-tryptophan|S-adenosyl-L-homocysteine|serotonin|melatonin|L-tryptophan|H+|N-acetyl-serotonin|4α-hydroxy-tetrahydrobiopterin|CO2|oxygen|coenzyme A
|
2
|
|
vitamin B6 degradation
|
PWY-5499
|
2-methyl-3-hydroxypyridine-4,5-dicarboxylate 4-decarboxylase|pyridoxamine-pyruvate aminotransferase|pyridoxamine-pyruvate aminotransferase [Ppat]4|α-(N-acetylaminomethylene)succiate hydrolase|2-methyl-3-hydroxypyridine-5-carboxylate oxygenase|4-pyridoxolactonase [Mlr6805]2|pyridoxine 4-oxidase pno|pyridoxal 4-dehydrogenase|pyridoxine 4-oxidase|4-pyridoxolactonase
|
4-pyridoxolactone|acetate|pyridoxamine|NAD+|succinate semialdehyde|5-formyl-3-hydroxy-2-methylpyidine-4-carboxylate|pyridoxine|H2O|L-alanine|CO2|4-pyridoxate|3-hydroxy-2-methylpyridine-4,5-dicarboxylate|3-hydroxy-2-methylpyridine-5-carboxylate|hydrogen peroxide|H+|ammonium|2-(acetamidomethylene)succinate|pyridoxal|pyruvate|NADH|oxygen
|
2
|
|
curcuminoid biosynthesis
|
PWY-6432
|
curcumin synthase|curcumin synthase CURS3|diketide-CoA synthase DCS|diketide-CoA synthase
|
H2O|4-coumaroylacetyl-CoA|trans-cinnamate|curcumin|feruloyl-CoA|bisdemethoxycurcumin|CO2|(E)-cinnamoyl-CoA|4-coumaroyl-CoA|H+|demethoxycurcumin|ammonium|feruloylacetyl-CoA|malonyl-CoA|diphosphate|L-phenylalanine|coenzyme A
|
2
|
|
superpathway of scopolin and esculin biosynthesis
|
PWY-7186
|
cinnamate 4-hydroxylase ATC4H|UDP-glucose:scopoletin O-β-D-glucosyltransferase TOGT1
|
S-adenosyl-L-methionine|NADPH|(E)-6-hydroxyferulate|ammonium|CO2|H2O|(Z)-2,4-dihydroxycinnamate|NADP+|trans-cinnamate|trans-caffeate|scopolin|ferulate|scopoletin|L-phenylalanine|UDP-α-D-glucose|umbelliferone|4-coumarate|esculetin|succinate|oxygen|esculin|(E)-2,4-dihydroxycinnamate|(Z)-6-hydroxyferulate|H+|S-adenosyl-L-homocysteine|2-oxoglutarate
|
2
|
|
cholesterol biosynthesis III (via desmosterol)
|
PWY66-4
|
lanosterol synthase|3-keto-steroid reductase|lamin B receptor|3-β-hydroxysteroid-Δ8-Δ7-isomerase|3-β-hydroxysteroid-Δ8-Δ7-isomerase [EBP]4|24-dehydrocholesterol reductase precursor|squalene monooxygenase|cytochrome P450 51A1|C-4 methyl sterol oxidase|farnesyl-diphosphate farnesyltransferase|NAD(P)-dependent 3β-hydroxy-4α-carboxy-sterol 3-dehydrogenase (decarboxylating)|Δ 7-sterol reductase|lathosterol oxidase
|
14-hydroxylanosterol|NADPH|4α-carboxy-5α-cholesta-8,24-dien-3β-ol|zymosterol|4,4-dimethyl-cholesta-8,12,24-trienol|cholesterol|4,4-dimethylzymosterol|4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol|4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol|H2O|5α-cholesta-8,24-dien-3-one|(3S)-2,3-epoxy-2,3-dihydrosqualene|7-dehydrodesmosterol|NADP+|4α-methyl-zymosterol|formate|CO2|4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol|3-dehydro-4-methylzymosterol|oxygen|diphosphate|14-oxolanosterol|squalene|5α-cholesta-7,24-dien-3β-ol|4α-formyl-5α-cholesta-8,24-dien-3β-ol|lanosterol|desmosterol|H+|4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol|(2E,6E)-farnesyl diphosphate
|
1
|
|
cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
|
PWY66-3
|
lamin B receptor LBR|24-dehydrocholesterol reductase precursor|C-4 methyl sterol oxidase SC4MOL|3-keto-steroid reductase|lamin B receptor|NAD(P)-dependent 3β-hydroxy-4α-carboxy-sterol 3-dehydrogenase (decarboxylating) NSDHL|3-β-hydroxysteroid-Δ8-Δ7-isomerase|3-β-hydroxysteroid-Δ8-Δ7-isomerase [EBP]4|cytochrome P450 51A1|cytochrome P450 51A1 CYP51A1|squalene monooxygenase|Δ 7-sterol reductase DHCR7|lathosterol oxidase SC5DL|Δ 7-sterol reductase|C-4 methyl sterol oxidase|farnesyl-diphosphate farnesyltransferase|NAD(P)-dependent 3β-hydroxy-4α-carboxy-sterol 3-dehydrogenase (decarboxylating)|lanosterol synthase|3-keto-steroid reductase HSD17B7|24-dehydrocholesterol reductase precursor DHCR24|lathosterol oxidase
|
NADPH|lathosterol|cholesterol|24,25-dihydrolanosterol|4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol|H2O|(3S)-2,3-epoxy-2,3-dihydrosqualene|NADP+|4α-carboxy-5α-cholesta-8-en-3β-ol|formate|CO2|4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol|4α-hydroxymethyl-5α-cholesta-8-en-3β-ol|4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol|4α-formyl-5α-cholesta-8-en-3β-ol|4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol|5α-cholesta-8-en-3-one|4α-methyl-5α-cholesta-8-en-3-one|oxygen|4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol|4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol|4α-methyl-cholesta-8-enol|diphosphate|squalene|4,4-dimethyl-5α-cholesta-8-en-3-β-ol|lanosterol|H+|zymostenol|7-dehydrocholesterol|(2E,6E)-farnesyl diphosphate
|
1
|
|
abscisic acid biosynthesis
|
PWY-695
|
aldehyde oxidase / indole-3-acetaldehyde oxidase / abscisic aldehyde oxidase|xanthoxin dehydrogenase ABA2|aldehyde oxidase / indole-3-acetaldehyde oxidase / abscisic aldehyde oxidase [AAO3]2|xanthoxin dehydrogenase|neoxanthin synthase|9-cis-epoxycarotenoid dioxygenase
|
2-cis,4-trans-xanthoxin|H2O|NAD+|(+)-cis-abscisic aldehyde|2-cis-abscisate|trans-neoxanthin|(3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12-apo-β-caroten-12-al|9-cis-neoxanthin|hydrogen peroxide|H+|NADH|oxygen
|
1
|