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superpathway of fatty acid biosynthesis initiation (E. coli)
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FASYN-INITIAL-PWY
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KASIII|KASI [FabB]2|KASI|KASII|acetyl-CoA carboxylase|malonyl-CoA-ACP transacylase
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acetyl-CoA|hydrogen carbonate|H+|phosphate|malonyl-CoA|CO2|coenzyme A
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187
|
|
pyrimidine deoxyribonucleotides de novo biosynthesis III
|
PWY-6545
|
dUTPase|thymidylate kinase|nucleoside-triphosphatase|nucleoside-diphosphate kinase|ribonucleotide reductase|B12-dependent ribonucleotide reductase|flavin-dependent thymidylate synthase
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H2O|NADPH|diphosphate|NADP+|H+|phosphate|a 5,10-methylene-tetrahydrofolate|a tetrahydrofolate
|
185
|
|
peptidoglycan biosynthesis I (meso-diaminopimelate containing)
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PEPTIDOGLYCANSYN-PWY
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UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase|UDP-N-acetylglucosamine enolpyruvoyl transferase|D-alanine-D-alanine ligase B|glutamate racemase|phospho-N-acetylmuramoyl-pentapeptide transferase|UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase|D-alanyl-D-alanine-adding enzyme|UDP-N-acetylmuramate-alanine ligase|N-acetylglucosaminyl transferase murG|phospho-N-acetylmuramoyl-pentapeptide transferase mraY|N-acetylglucosaminyl transferase|D-alanine-D-alanine ligase A|UDP-N-acetylenolpyruvoylglucosamine reductase
|
UDP-N-acetyl-α-D-glucosamine-enolpyruvate|undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine|NADPH|di-trans,octa-cis-undecaprenyl phosphate|meso-diaminopimelate|UDP-N-acetyl-α-D-muramate|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate|NADP+|L-alanine|UDP-N-acetyl-α-D-glucosamine|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine|L-glutamate|phosphoenolpyruvate|D-alanine|H+|phosphate|D-alanyl-D-alanine|D-glutamate|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine|UDP-N-acetyl-α-D-muramoyl-L-alanine
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183
|
|
glycolysis I (from glucose 6-phosphate)
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GLYCOLYSIS
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phosphoglycerate kinase|pyruvate kinase|glucose-6-phosphate isomerase|glyceraldehyde 3-phosphate dehydrogenase|pyruvate kinase I|phosphoglucose isomerase|fructose bisphosphate aldolase class I|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase|6-phosphofructokinase I|fructose bisphosphate aldolase class II|pyridoxal phosphatase / fructose 1,6-bisphosphatase|triosephosphate isomerase|glucose 6-phosphate isomerase|fructose-bisphosphate aldolase|fructose 1,6-bisphosphatase II|chloroplastic glyceraldehyde 3-phosphate dehydrogenase|plastidic cofactor-independent phosphoglycerate mutase|fructose-1,6-bisphosphatase I|enolase|plastidic enolase|plastidic phosphoglucose isomerase|phosphoenolpyruvate synthetase|enolase, subunit of degradosome|chloroplastic fructose-bisphosphate aldolase|plastidic 3-phosphoglycerate kinase|6-phosphofructokinase II|plastidic pyruvate kinase|chloroplastic 6-phosphofructokinase|glyceraldehyde-3-phosphate dehydrogenase|6-phosphofructokinase|pyruvate kinase II|fructose-1,6-bisphosphatase|2,3-bisphosphoglycerate-independent phosphoglycerate mutase
|
H2O|NAD+|3-phospho-D-glycerate|D-glucopyranose 6-phosphate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|phosphoenolpyruvate|glycerone phosphate|β-D-fructofuranose 6-phosphate|D-glyceraldehyde 3-phosphate|H+|phosphate|pyruvate|NADH|1,3-bisphospho-D-glycerate
|
182
|
|
gondoate biosynthesis (anaerobic)
|
PWY-7663
|
enoyl-[acyl-carrier-protein] reductase|3-hydroxyacyl-[acyl-carrier-protein] dehydratase/isomerase [FabQ]6|3-oxoacyl-[acyl-carrier-protein] reductase fabG|enoyl-[acyl-carrier-protein] reductase fabK|3-oxoacyl-[acyl-carrier-protein] synthase|3-hydroxyacyl-[acyl-carrier-protein] dehydratase/isomerase|3-oxoacyl-[acyl-carrier-protein] synthase fabF|3-oxoacyl-[acyl-carrier-protein] reductase
|
H2O|NAD+|NADP+|CO2|H+|NADPH|NADH
|
182
|
|
gluconeogenesis I
|
GLUCONEO-PWY
|
phosphoglycerate kinase|glyceraldehyde 3-phosphate dehydrogenase|phosphoenolpyruvate synthetase|NAD-dependent glyceraldehyde-3-phosphate dehydrogenase|phosphoglucose isomerase|fructose bisphosphate aldolase class I|cytoplasmic enolase|pyridoxal phosphatase / fructose 1,6-bisphosphatase|cytoplasmic 2,3-bisphosphoglycerate-independent phosphoglycerate mutase|triosephosphate isomerase|cytosolic fructose-1,6-biphosphate aldolase|fructose 1,6-bisphosphatase II|chloroplastic glyceraldehyde 3-phosphate dehydrogenase|plastidic cofactor-independent phosphoglycerate mutase|fructose-1,6-bisphosphatase I|cytosolic triose phosphate isomerase|enolase, subunit of degradosome|plastidic enolase|chloroplastic fructose-bisphosphate aldolase|malate dehydrogenase (NAD)|cytosolic enolase|phosphoenolpyruvate carboxykinase (ATP)|NADP malic enzyme|malate dehydrogenase, NAD-requiring|fructose-1,6-bisphosphatase|cytosolic triose-phosphate isomerase|cytosolic cofactor-independent phosphoglycerate mutase|2,3-bisphosphoglycerate-independent phosphoglycerate mutase|malate dehydrogenase
|
H2O|2-phospho-D-glycerate|NAD+|phosphate|3-phospho-D-glycerate|D-glucopyranose 6-phosphate|(S)-malate|NADP+|phosphoenolpyruvate|CO2|β-D-fructofuranose 6-phosphate|oxaloacetate|fructose 1,6-bisphosphate|D-glyceraldehyde 3-phosphate|H+|NADPH|glycerone phosphate|pyruvate|NADH|1,3-bisphospho-D-glycerate
|
181
|
|
cis-vaccenate biosynthesis
|
PWY-5973
|
3-hydroxy-acyl-[acyl-carrier-protein] dehydratase|multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 [TesA]4|multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1|KASII|KASII [FabF]2|3-oxoacyl-[acyl-carrier-protein] reductase|enoyl-[acyl-carrier-protein] reductase
|
H2O|NAD+|NADP+|CO2|H+|NADPH|cis-vaccenate|NADH
|
180
|
|
superpathway of Clostridium acetobutylicum solventogenic fermentation
|
PWY-6594
|
butyryl-CoA dehydrogenase|NADH-dependent butanol dehydrogenase B|alcohol/aldehyde dehydrogenase|NADH-dependent butanol dehydrogenase A|pyruvate:ferredoxin oxidoreductase|3-hydroxybutyryl-CoA dehydratase|butyrate--acetoacetate CoA-transferase|3-hydroxybutyryl-CoA dehydrogenase|acetoacetate decarboxylase|acetyl-CoA C-acetyltransferase|NADPH-dependent butanol dehydrogenas|aldehyde/alcohol dehydrogenase|(S)-3-hydroxybutyryl-CoA dehydrogenase
|
NADPH|(S)-3-hydroxybutanoyl-CoA|butanoyl-CoA|crotonyl-CoA|H2O|NAD+|acetyl-CoA|butanoate|1-butanol|NADP+|acetaldehyde|acetoacetyl-CoA|coenzyme A|1-butanal|CO2|ethanol|acetate|acetone|pyruvate|acetoacetate|H+|NADH
|
179
|
|
superpathway of L-methionine biosynthesis (by sulfhydrylation)
|
PWY-5345
|
cobalamin-independent homocysteine transmethylase|aspartate semialdehyde dehydrogenase|aspartokinase|phosphoadenosine phosphosulfate reductase|O-acetylhomoserine sulfhydrylase|sulfate adenylyltransferase|aspartate kinase III|cobalamin-independent methionine synthase|homoserine O-acetyltransferase|adenylylsulfate kinase|homocysteine methyltransferase|cob(I)alamin-dependent methionine synthase|aspartate kinase II|assimilatory sulfite reductase (NADPH)|aspartate aminotransferase
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NADPH|sulfate|3-phosphoadenylyl-sulfate|L-methionine|H2O|acetyl-CoA|L-homocysteine|NADP+|adenosine 3,5-bisphosphate|oxaloacetate|sulfite|L-glutamate|L-homoserine|phosphate|acetate|N5-methyl--tetrahydropteroyl tri-L-glutamate|a tetrahydrofolate|L-aspartyl-4-phosphate|tetrahydropteroyl tri-L-glutamate|an N5-methyl-tetrahydrofolate|O-acetyl-L-homoserine|adenosine 5-phosphosulfate|coenzyme A|hydrogen sulfide|diphosphate|L-aspartate-semialdehyde|L-aspartate|H+|2-oxoglutarate
|
171
|
|
phytol degradation
|
PWY66-389
|
4-trimethylaminobutyraldehyde dehydrogenase|fatty aldehyde dehydrogenase|peroxisomal trans-2-enoyl-CoA reductase|medium-chain acyl-CoA synthetase FAA2
|
phytanoyl-CoA|H2O|phytenal|NADPH|phytenate|phytenoyl-CoA|diphosphate|NADP+|H+|NAD+|phytol|NADH|coenzyme A
|
169
|