|
nicotinate degradation I
|
PWY-722
|
2,5-dihydroxypyridine dioxygenase|6-hydroxynicotinate 3-monooxygenase|maleamate amidohydrolase|nicotinate dehydrogenase (cytochrome)|N-formylmaleamate deformylase|maleate cis-trans isomerase
|
N-formylmaleamate|fumarate|H2O|NAD+|nicotinate|maleamate|maleate|CO2|2,5-dihydroxypyridine|6-hydroxynicotinate|H+|ammonium|formate|NADH|oxygen
|
3
|
|
nicotine degradation III (VPP pathway)
|
PWY-7128
|
2,5-dihydroxypyridine dioxygenase|nicotine dehydrogenase, subunit of nicotine dehydrogenase/6-hydroxypseudooxynicotine oxidase complex|6-hydroxypseudooxynicotine oxidase|maleamate amidohydrolase|6-hydroxypseudooxynicotine oxidase, subunit of nicotine dehydrogenase/6-hydroxypseudooxynicotine oxidase complex|N-formylmaleamate deformylase|6-hydroxy-3-succinoyl-pyridine hydroxylase|(S)-6-hydroxynicotine oxidase|maleate isomerase
|
fumarate|maleamate|NADPH|6-hydroxy-N-methylmyosmine|(S)-nicotine|ammonium|4-(6-hydroxy-pyridin-3-yl)-4-oxobutanal|H2O|NAD+|succinate semialdehyde|NADP+|formate|methylamine|N-formylmaleamate|hydrogen peroxide|oxygen|6-hydroxy-3-succinoyl-pyridine|(S)-6-hydroxynicotine|maleate|2,5-dihydroxypyridine|6-hydroxypseudooxynicotine|H+|NADH
|
3
|
|
flavonoid biosynthesis
|
PWY1F-FLAVSYN
|
flavonol synthase/flavanone 3-dioxygenase|sinapate coenzyme A ligase / 4-coumarate coenzyme A ligase|4-coumarate coenzyme A ligase 2|4-coumarate coenzyme A ligase 3|flavanone 3β-hydroxylase|chalcone isomerase|chalcone isomerase 1|chalcone reductase|naringenin chalcone synthase|4-coumarate coenzyme A ligase 1
|
H2O|NADPH|2-oxoglutarate|diphosphate|NADP+|(+)-dihydrokaempferol|4-coumarate|2,4,4,6-tetrahydroxychalcone|4-coumaroyl-CoA|H+|malonyl-CoA|succinate|CO2|oxygen|coenzyme A
|
3
|
|
naringenin biosynthesis (engineered)
|
PWY-7397
|
chalcone isomerase 1|naringenin-chalcone synthase|phenylalanine/tyrosine ammonia-lyase [PAL]4|phenylalanine/tyrosine ammonia-lyase|4-coumarate--CoA ligase 1
|
L-tyrosine|diphosphate|4-coumarate|2,4,4,6-tetrahydroxychalcone|4-coumaroyl-CoA|H+|ammonium|malonyl-CoA|CO2|coenzyme A
|
3
|
|
(+)-camphor degradation
|
P601-PWY
|
2-oxo-Δ3-4,5,5-trimethylcyclopentenyl acetyl coA 1,2-monooxygenase [CamG]2|5-exo-hydroxycamphor dehydrogenase|2-oxo-Δ3-4,5,5-trimethylcyclopentenyl acetyl coA synthase|cytochrome P-450cam camC|2-oxo-Δ3-4,5,5-trimethylcyclopentenyl acetyl coA synthase [CamF1][CamF2]|cytochrome P-450cam, subunit of camphor 5-monooxygenase system|2,5-diketocamphane 1,2-monooxygenase complex|5-exo-hydroxycamphor dehydrogenase camD|2-oxo-Δ3-4,5,5-trimethylcyclopentenyl acetyl coA 1,2-monooxygenase|2,5-diketocamphane 1,2-monooxygenase complex [(Fred)2][(CamE25-2)2]
|
isobutanoyl-CoA|Δ2,5-3,4,4-trimethylpimeloyl-CoA|H2O|NAD+|acetyl-CoA|diphosphate|(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-ylacetyl-CoA|NADP+|(+)-bornane-2,5-dione|(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enylacetyl-CoA|(+)-5-oxo-1,2-campholide|(1R)-4,5,5-trimethyl-2-oxocyclopent-3-enylacetate|(+)-exo-5-hydroxycamphor|(+)-camphor|H+|NADPH|NADH|oxygen|coenzyme A
|
3
|
|
2-aminophenol degradation
|
PWY-6210
|
2-aminomucoate semialdehyde dehydrogenase|2-aminomuconic 6-semialdehyde dehydrogenase|4-oxalocrotonate decarboxylase|2-aminophenol 1,6-dioxygenase|2-aminophenol-1,6-dioxygenase|2-aminomuconate deaminase
|
H2O|NAD+|2-aminophenol|2-oxopent-4-enoate|(2Z,4E)-2-amino-6-oxohexa-2,4-dienoate|(2Z,4E)-2-aminomuconate|CO2|H+|ammonium|(3E)-2-oxohex-3-enedioate|NADH|oxygen
|
3
|
|
androgen biosynthesis
|
PWY66-378
|
3-oxo-5-alpha-steroid 4-dehydrogenase 1|steroid 17-alpha-hydroxylase/17,20 lyase|3-oxo-5-alpha-steroid 4-dehydrogenase 2|3 β-hydroxysteroid dehydrogenase/ Δ 5-->4-isomerase type 1|testosterone 17-beta-dehydrogenase 3|steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1|3 β-hydroxysteroid dehydrogenase/ Δ 5-->4-isomerase type 2|Aldo-keto reductase family 1 member C3
|
pregnenolone|H2O|testosterone|NAD+|17-β-hydroxy-5-α-androstan-3-one|NADP+|acetaldehyde|5-androstene-3,17-dione|dehydroepiandrosterone|H+|androst-4-ene-3,17-dione|NADPH|17-α-hydroxypregnenolone|NADH|oxygen
|
3
|
|
coenzyme B biosynthesis
|
P241-PWY
|
methanogen homoaconitase [AksD]2[AksE]2|methanogen homoaconitase|NAD-dependent threo-isocitrate dehydrogenase|(R)-homocitrate synthase|(R)-homocitrate synthase aksA|NAD-dependent threo-isocitrate dehydrogenase aksF
|
2-oxoadipate|cis-homoaconitate|(1R,2S)-homoisocitrate|cis-(homo)2aconitate|coenzyme B|2-oxosuberate|H2O|NAD+|acetyl-CoA|dihomocitrate|7-mercaptoheptanoate|(-)threo-iso(homo)3citrate|phosphate|7-mercaptoheptanoylthreonine|CO2|(-)threo-iso(homo)2citrate|(2R)-homocitrate|L-threonine|trihomocitrate|coenzyme A|2-oxopimelate|S2-|cis-(homo)3aconitate|7-oxoheptanoate|H+|2-oxoglutarate|NADH
|
3
|
|
fructan biosynthesis
|
PWY-822
|
1,2-β-fructan 1F-fructosyltransferase [Fft-1]|sucrose:sucrose 1-fructosyltransferase|fructan:fructan 6G-fructosyltransferase|fructan:fructan 6G-fructosyltransferase [6G-FFT]|sucrose:sucrose 1-fructosyltransferase [Sst-1]|1,2-β-fructan 1F-fructosyltransferase|sucrose:fructan 6-fructosyltransferase
|
1,1-kestotetraose|sucrose|6-kestotriose|1-kestotriose|1,6-kestotetraose|6G-kestotriose
|
3
|
|
gallate degradation I
|
GALLATE-DEGRADATION-II-PWY
|
4-oxalmesaconate hydratase|gallate dioxygenase|protocatechuate 4,5-dioxygenase|4-oxalomesaconate hydratase|4-carboxy-2-hydroxymuconate hydratase|4-oxalomesaconate tautomerase galD|4-oxalomesaconate tautomerase|oxaloacetate β-decarboxylase / 4-oxalocitramalate aldolase|HMG aldolase
|
H2O|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate|gallate|(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate|(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate|oxaloacetate|H+|pyruvate|oxygen
|
3
|