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L-lysine biosynthesis V
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PWY-3081
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[LysW]-L-2-aminoadipate 6-phosphate reductase|L-2-aminoadipate carrier protein]-lysine/ornithine hydrolase|[LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase|L-2-aminoadipate aminotransferase|[L-2-aminoadipate carrier protein]-L-lysine lysine-hydrolase|L-2-aminoadipate--LysW ligase [LysX]2|homocitrate synthase|homoaconitase|[LysW]-L-2aminoadipate 6-kinase|homoisocitrate dehydrogenase|[LysW]-L-2-aminoadipate semialdehyde transaminase|[LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase|[LysW]-L-2-aminoadipate 6-kinase|[LysW}-glutamate/[LysW]-aminoadipate kinase|L-2-aminoadipate--LysW ligase
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NADPH|2-oxoadipate|a LysW-C-terminal-L-glutamyl-γ-L-2-aminoadipate 6-phosphate|cis-homoaconitate|a LysW-C-terminal-L-glutamyl-γ-L-lysine|(1R,2S)-homoisocitrate|a LysW-C-terminal-L-glutamyl-γ-L-2-aminoadipate|H2O|NAD+|acetyl-CoA|L-2-aminoadipate|NADP+|L-glutamate|phosphate|CO2|(2R)-homocitrate|a LysW-C-terminal-L-glutamyl-γ-L-2-aminoadipate semialdehyde|L-lysine|coenzyme A|H+|2-oxoglutarate|NADH
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4
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methanol oxidation to carbon dioxide
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PWY-7616
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mycothiol-dependent formaldehyde dehydrogenase|acetaldehyde dehydrogenase|Zn2+-dependent alcohol dehydrogenase|formate dehydrogenase
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H2O|NAD+|S-formylmycothiol|methanol|formaldehyde|S-hydroxymethylmycothiol|CO2|H+|formate|NADH|mycothiol
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4
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plant sterol biosynthesis
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PWY-2541
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squalene synthase|Δ8-Δ7-sterol isomerase HYD1|4-α-methyl-Δ7-sterol-4α-methyl oxidase SMO2-1|cycloeucalenol cycloisomerase|3β-hydroxysteroid dehydrogenase/C4-decarboxylase|4-α-methyl-Δ7-sterol-4α-methyl oxidase|C-22 sterol desaturase CYP710A2|obtusifoliol-14α-demethylase|Δ5-sterol-Δ24- reductase|Δ7-sterol-C5-desaturase DWF7|obtusifoliol 14α-demethylase|Δ8,14sterol Δ14-sterol reductase FK|sterone reducatase|sterol methyltransferase|4,4-dimethyl-9β,19-cyclopropylsterol-4α-methyl oxidase|sterol 24C methyltransferase|sterol Δ7 reductase|cycloartenol synthase|Δ7-sterol-C5-desaturase|squalene monooxygenase|4,4-dimethyl-9β,19-cyclopropylsterol-4α-methyl oxidase SMO1-1|cycloeucalenol cycloisomerase CPI1|Δ5-sterol-Δ24- reductase DWF1|C-22 sterol desaturase|Δ8,14sterol Δ14-sterol reductase|Δ8-Δ7-sterol isomerase|sterol Δ7 reductase DWF5
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S-adenosyl-L-methionine|cycloeucalenone|NADPH|brassicasterol|cycloartenol|4α-methyl-5α-ergosta-8,24-dien-3β-ol|4α-formyl-ergosta-7,24(241)-dien-3β-ol|S-adenosyl-L-homocysteine|5-dehydroavenasterol|4α-hydroxymethyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol|24-ethylidenelophenol|avenastenone|H2O|NAD+|(3S)-2,3-epoxy-2,3-dihydrosqualene|avenasterol|4α-formyl-stigmasta-7,24(241)-dien-3β-ol|NADP+|4α-hydroxymethyl-ergosta-7,24(241)-dien-3β-ol|4α-carboxy-ergosta-7,24(241)-dien-3β-ol|24-methyldesmosterol|stigmasterol|formate|CO2|24-epi-campesterol|episterol|4α-hydroxymethyl-stigmasta-7,24(241)-dien-3β-ol|episterone|4α-carboxy-4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol|4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol|obtusifoliol|4α-formyl,4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(241)-en-3β-ol|Δ24-25-sitosterol|oxygen|isofucosterol|cycloeucalenol|ergosta-5,7,24(28)-trien-3β-ol|24-methylenecycloartanol|campesterol|squalene|24-methylenecholesterol|NADH|sitosterol|crinosterol|H+|4α-carboxy-stigmasta-7,24(241)-dien-3β-ol|24-methylenelophenol|diphosphate|(2E,6E)-farnesyl diphosphate
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4
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sphingolipid biosynthesis (yeast)
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SPHINGOLIPID-SYN-PWY
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3-dehydrosphinganine reductase|ceramide synthase [LIP1][LAG1][LAC1]|mannosyl-inositol-phosphoceramide inositolphosphotransferase|ceramide synthase|inositol phosphorylceramide mannosyltransferase|inositol phosphorylceramide synthase|sphingolipid C4-hydroxylase|serine palmitoyltransferase|ceramide very long chain fatty acid hydroxylase|mannosyl-inositol-phosphoceramide inositolphosphotransferase IPT1
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H2O|L-serine|NADPH|3-dehydrosphinganine|palmitoyl-CoA|phytosphingosine|NADP+|GDP-α-D-mannose|a 1,2-diacyl-sn-glycerol|an inositol-phospho-α hydroxyphytoceramide|D-erythro-sphinganine|H+|a mannosyl-diphosphoinositol-α hydroxyphytoceramide|CO2|oxygen|coenzyme A
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4
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starch degradation II
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PWY-6724
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disproportionating enzyme|phosphoglucan, water dikinase|β-amylase BAM3|glucan, water dikinase GWD|glucan, water dikinase|isoamylase|glucan phosphatase|isoamylase ISA3|glucan phosphatase SEX4|β-amylase|phosphoglucan, water dikinase PWD
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phosphate|H2O|maltotriose|an exposed unphosphorylated, (α-1,6)-branched malto-oligosaccharide tail on amylopectin
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4
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superpathway of CDP-glucose-derived O-antigen building blocks biosynthesis
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PWY-5823
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CDP-3, 6-dideoxy-D-glycero-L-glycero-4-hexulose-4-reductase|CDP-4-dehydro-6-deoxyglucose reductase|CDP-3, 6-dideoxy-D-glycero-D-glycero-4-hexulose-5-epimerase|CDP-paratose synthase [RfbS]2|CDP-paratose 2-epimerase rfbE|CDP-abequose synthase rfbJ|CDP-D-glucose-4,6-dehydratase [AscB]2|CDP-abequose synthase|α-D-glucose-1-phosphate cytidylyltransferase|CDP-D-glucose-4,6-dehydratase|CDP-paratose synthase|α-D-glucose-1-phosphate cytidylyltransferase [AscA]4|CDP-paratose 2-epimerase|CDP-4-dehydro-6-deoxyglucose reductase [AscC][AscD]
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H2O|NADPH|CDP-α-D-tyvelose|CDP-4-dehydro-3,6-dideoxy-D-glucose|diphosphate|α-D-glucopyranose 1-phosphate|NADP+|CDP-4-dehydro-3,6-dideoxy-D-glucose epimer|CDP-α-D-abequose|CDP-α-D-paratose|H+|CDP-α-D-glucose|CDP-4-dehydro-6-deoxy-D-glucose|CDP-ascarylose
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4
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UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronate biosynthesis
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PWY-7090
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UDP-N-acetyl-α-D-glucosamine 6-dehydrogenase|UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase wbpI|UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase|UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase wbpE|UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase|UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase wbpB|UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase [WbpD]3|UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase|UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase
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H2O|UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate|NAD+|UDP-N-acetyl-α-D-glucosaminouronate|acetyl-CoA|UDP-2,3-diacetamido-2,3-dideoxy-α-D-glucuronate|UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronate|UDP-2-acetamido-3-amino-2,3-dideoxy-α-D-glucuronate|UDP-N-acetyl-α-D-glucosamine|L-glutamate|H+|2-oxoglutarate|NADH|coenzyme A
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4
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vitamin E biosynthesis (tocopherols)
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PWY-1422
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tocopherol cyclase|2-methyl-6-phytyl-1,4-benzoquinone methyltransferase [multifunctional]|δ-tocotrienol methyltransferase [multifunctional]|4-hydroxyphenylpyruvate dioxygenase|2-methyl-6-phytyl-1,4-hydroquinone methyltransferase|tocopherol methyltransferase|homogentisate phytyltransferase
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S-adenosyl-L-methionine|homogentisate|β-tocopherol|γ-tocopherol|δ-tocopherol|diphosphate|4-hydroxyphenylpyruvate|2,3-dimethyl-6-phytyl-1,4-benzoquinol|phytyl diphosphate|H+|S-adenosyl-L-homocysteine|2-methyl-6-phytyl-1,4-benzoquinol|CO2|oxygen
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4
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chondroitin sulfate degradation I (bacterial)
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PWY-6572
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chondroitin sulfate ABC exolyase ChABCII|unsaturated β-glucuronyl hydrolase|chondroitin ABC endo-lyase|chondroitin AC lyase|unsaturated β-glucuronyl hydrolase ugl|chondro-6-sulfatase|chondro-4-sulfatase|chondroitin sulfate ABC exolyase
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4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate|H2O|4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl--D-galactosamine 6-sulfate|4-deoxy-L-threo-hex-4-enopyranuronate|N-acetyl-D-galactosamine 6-O-sulfate|sulfate|H+|4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine|N-acetyl-D-galactosamine
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4
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pyruvate fermentation to opines
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PWY-7351
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β-alanopine dehydrogenase beta-AlDH|octopine dehydrogenase|β-alanopine dehydrogenase|strombine/alanopine dehydrogenase|alanopine dehydrogenase|strombine/alanopine dehydrogenase St/AlDH|tauropine dehydrogenase
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D-octopine|H2O|NAD+|glycine|strombine|β-alanopine|L-alanine|tauropine|L-arginine|H+|taurine|pyruvate|NADH|β-alanine
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4
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