|
mannitol cycle
|
PWY-6531
|
mannitol dehydrogenase|mannitol-1-phosphate 5-dehydrogenase|mannitol-1-phosphatase|hexokinase|24323504
|
H2O|NAD+|D-mannitol 1-phosphate|β-D-fructofuranose 6-phosphate|D-mannitol|keto-D-fructose|H+|phosphate|β-D-fructofuranose|NADH
|
18
|
|
superpathway of ubiquinol-6 biosynthesis (eukaryotic)
|
PWY-7235
|
5-demethoxyubiquinol hydroxylase COQ7|2-hexaprenyl-6-methoxy-1,4-benzoquinol methyltransferase|hexaprenyldihydroxybenzoate methyltransferase COQ3|hexaprenyldihydroxybenzoate methyltransferase|Yeast Adrenodoxin Homolog|3-hexaprenyl-benzoate-5-monoxygenase COQ6|hexaprenyl-diphosphate hexaprenyltransferase|ferredoxin oxidoreductase|2-hexaprenyl-6-methoxy-1,4-benzoquinol methyltransferase COQ5|3-hexaprenyl-benzoate-5-monoxygenase|hexaprenyl-diphosphate hexaprenyltransferase COQ2|5-demethoxyubiquinol hydroxylase
|
S-adenosyl-L-methionine|NADPH|3-demethylubiquinol-6|2-hexaprenyl-6-methoxyphenol|ammonium|2-hexaprenyl-6-methoxyaminophenol|H2O|2-hexaprenyl-3-methyl-6-methoxyaminophenol|NADP+|all-trans-hexaprenyl diphosphate|3-hexaprenyl-4-amino-5-methoxybenzoate|4-hydroxybenzoate|2-hexaprenyl-6-methoxyaminobenzene|S-adenosyl-L-homocysteine|2-methoxy-6-all trans-hexaprenyl-2-methoxy-1,4-benzoquinol|3-hexaprenyl-4-amino-5-hydroxybenzoate|oxygen|3-hexaprenyl-4-hydroxybenzoate|diphosphate|3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate|ubiquinol-6|CO2|4-aminobenzoate|3-hexaprenyl-4-aminobenzoate|6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol|H+|3,4-dihydroxy-5-all-trans-hexaprenylbenzoate
|
18
|
|
toluene degradation I (aerobic) (via o-cresol)
|
PWY-5180
|
toluene ortho-monooxygenase [(TomA3)2(TomA1)2(TomA4)2][TomA5][TomA2]|catechol 2,3-dioxygenase|2-hydroxy-6-oxohepta-2,4-dienoate hydrolase|toluene ortho-monooxygenase
|
acetate|NAD+|acetyl-CoA|3-methylcatechol|2-methylphenol|4-hydroxy-2-oxopentanoate|H2O|acetaldehyde|2-oxopent-4-enoate|H+|toluene|cis,cis-2-hydroxy-6-oxohepta-2,4-dienoate|pyruvate|NADH|oxygen|coenzyme A
|
18
|
|
4-hydroxyphenylacetate degradation
|
3-HYDROXYPHENYLACETATE-DEGRADATION-PWY
|
4-coumarate 3-monooxygenase|3,4-dihydroxyphenylacetate dioxygenase|2-hydroxyhepta-2,4-dienedioate hydratase|5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase|5-carboxymethyl-2-hydroxymuconate isomerase hpaF|2-hydroxyhepta-2,4-dienedioate hydratase [HpcG]6|4-coumarate 3-monooxygenase hpaB|4-hydroxy-2-ketopimelate aldolase|4-hydroxy-2-ketopimelate aldolase hpaI|2-hydroxy-5-carboxymethylmuconate semialdehyde dehydrogenase|5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase hpaG|2-hydroxy-5-carboxymethylmuconate semialdehyde dehydrogenase [HpaE]4|5-carboxymethyl-2-hydroxymuconate isomerase
|
H2O|NADPH|FAD|succinate semialdehyde|(4Z)-2-oxohept-4-enedioate|NADP+|2-hydroxy-5-carboxymethylmuconate semialdehyde|FADH2|(4S)-4-hydroxy-2-oxoheptanedioate|CO2|5-carboxymethyl-2-hydroxymuconate|4-hydroxyphenylacetate|succinate|(3E,5R)-5-carboxy-2-oxohept-3-enedioate|3,4-dihydroxyphenylacetate|H+|NAD+|pyruvate|NADH|oxygen
|
18
|
|
superpathway of 4-hydroxybenzoate biosynthesis (yeast)
|
PWY3O-1109
|
4-hydroxybenzoyl-CoA thioesterase [FcbC]4|aromatic amino acid aminotransferase I|hydroxyphenylpyruvate reductase HPPR
|
H2O|L-tyrosine|acetyl-CoA|4-coumarate|2-oxoglutarate|diphosphate|4-hydroxybenzoyl-CoA|4-hydroxyphenylpyruvate|chorismate|L-glutamate|4-coumaroyl-CoA|H+|NAD+|4-hydroxybenzoate|3-(4-hydroxyphenyl)lactate|pyruvate|NADH|coenzyme A
|
18
|
|
adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I
|
PWY-5509
|
CobO|adenosyl-cobyric acid synthase|adenosyl-cobyrate synthase|CobA|adenosylcobinamide-phosphate synthase|CobU|cob(II)yrinate a,c-diamide reductase|flavodoxin A|CobP|nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
|
α-ribazole 5-phosphate|5,6-dimethylbenzimidazole|H2O|adenosylcobyrate|diphosphate|PPPi|nicotinate|cob(I)yrinate a,c-diamide|adenosylcobinamide-GDP|(R)-1-amino-2-propanol O-2-phosphate|L-glutamate|cob(II)yrinate a,c-diamide|adenosylcobalamin 5-phosphate|H+|FMNH2|phosphate|adenosyl-cobinamide phosphate|L-glutamine|adenosyl-cobyrinate a,c-diamide|β-nicotinate D-ribonucleotide
|
17
|
|
adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II
|
PWY-5508
|
CobO|5,6-dimethylbenzimidazole synthase|adenosyl-cobyric acid synthase|adenosylcobinamide-phosphate synthase|5,6-dimethylbenzimidazole synthase bluB|cob(II)yrinate a,c-diamide reductase|CobP|nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
|
L-glutamine|cob(I)yrinate a,c-diamide|adenosylcobinamide-GDP|dialurate|H2O|adenosylcobyrate|PPPi|cob(II)yrinate a,c-diamide|L-glutamate|oxygen|5,6-dimethylbenzimidazole|adenosyl-cobinamide phosphate|D-erythrose 4-phosphate|nicotinate|phosphate|FMNH2|adenosyl-cobyrinate a,c-diamide|β-nicotinate D-ribonucleotide|α-ribazole 5-phosphate|α-ribazole|diphosphate|(R)-1-amino-2-propanol O-2-phosphate|H+
|
17
|
|
lipid IVA biosynthesis
|
NAGLIPASYN-PWY
|
UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase [LpxD]3|UDP-N-acetylglucosamine acyltransferase [LpxA]3|UDP-N-acetylglucosamine acyltransferase|UDP-2,3-diacylglucosamine hydrolase|UDP-2,3-diacylglucosamine hydrolase lpxH|lipid A disaccharide synthase|UDP-3-O-acyl-N-acetylglucosamine deacetylase lpxC|UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase|lipid A disaccharide synthase [LpxB]8
|
lipid IVA|H2O|UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine|UDP-2-N,3-O-bis(3R)-3-hydroxytetradecanoyl-α-D-glucosamine|acetate|UDP-3-O-(3R)-3-hydroxymyristoyl-N-acetyl-α-D-glucosamine|UDP-N-acetyl-α-D-glucosamine|2,3-bis(3R)-3-hydroxymyristoyl-α-D-glucosaminyl 1-phosphate|H+
|
17
|
|
bacilysin biosynthesis
|
PWY-7626
|
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate aminotransferase bacF|L-alanine-anticapsin ligase bacD|prephenate decarboxylase|L-alanine-anticapsin ligase|dihydroanticapsin dehydrogenase bacC|3-[(5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate reductase bacG|dihydroanticapsin dehydrogenase|chorismate mutase|3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate aminotransferase|3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase bacB|prephenate decarboxylase bacA|3-[(5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate reductase|chorismate mutase / DAHP synthase|3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase
|
H2O|3-(2E,5R)-5-hydroxy-7-oxabicyclo4.1.0heptan-2-ylidene-2-oxopropanoate|NAD+|3-(4R)-4-hydroxycyclohexa-1,5-dien-1-yl-2-oxopropanoate|2-oxo-3-phenylpropanoate|3-(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene-2-oxopropanoate|3-(2Z,5R)-5-hydroxy-7-oxabicyclo4.1.0heptan-2-ylidene-2-oxopropanoate|bacilysin|L-alanine|CO2|chorismate|prephenate|L-phenylalanine|H+|phosphate|3-(2S,5R)-5-hydroxy-7-oxabicyclo4.1.0heptan-2-yl-2-oxopropanoate|NADH|oxygen
|
17
|
|
4-methylcatechol degradation (ortho cleavage)
|
PWY-6185
|
muconate cycloisomerase I salC|methylmuconolactone isomerase|methylmuconolactone isomerase [MmlJ]10|4-methylcatechol 1,2-dioxygenase [multifunctional]|muconate cycloisomerase I|4-methylmuconolactone methylisomerase [MmlI]2|4-methylmuconolactone methylisomerase
|
4-methyl-3-oxoadipate-enol-lactone|H2O|3-methylmuconolactone|4-methylmuconolactone|acetyl-CoA|(2S)-methylsuccinyl-CoA|4-methyl-3-oxoadipyl-CoA|4-methyl-3-oxoadipate|H+|succinyl-CoA|4-methylcatechol|succinate|3-methyl-cis,cis-muconate|oxygen|coenzyme A
|
17
|