biotin biosynthesis II
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PWY-5005
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6-carboxyhexanoate-CoA ligase|6-carboxyhexanoate--CoA ligase|8-amino-7-oxononanoate synthase|lysine--8-amino-7-oxononanoate transaminase|dethiobiotin synthetase|biotin synthase
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S-adenosyl-L-methionine|L-methionine|dethiobiotin|8-amino-7-oxononanoate|pimeloyl-CoA|(S)-2-amino-6-oxohexanoate|diphosphate|biotin|7,8-diaminopelargonate|phosphate|L-alanine|L-lysine|H+|pimelate|5-deoxyadenosine|CO2|coenzyme A
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22
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ketogluconate metabolism
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KETOGLUCONMET-PWY
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glyoxylate reductase [multifunctional] [GhrB]2|D-gluconate kinase, thermosensitive|glyoxylate reductase [multifunctional]|L-idonate 5-dehydrogenase|2,5-didehydrogluconate reductase|5-keto-D-gluconate 5-reductase idnO|L-idonate 5-dehydrogenase idnD|2,5-diketo-D-gluconate reductase A|methylglyoxal reductase [multifunctional]|5-keto-D-gluconate 5-reductase
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D-gluconate|NADPH|2-keto-D-gluconate|D-gluconate 6-phosphate|2-keto-L-gulonate|NADP+|2,5-didehydro-D-gluconate|L-idonate|H+|5-dehydro-D-gluconate
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22
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naphthalene degradation to acetyl-CoA
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PWY-6956
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cis-1,2-dihydro-1,2-dihydroxynaphthalene-1, 2-dehydrogenase|2-hydroxymuconic semialdehyde hydrolase xylF|salicylaldehyde dehydrogenase|2-hydroxychromene-2-carboxylate isomerase [NahD]2|naphthalene 1,2-dioxygenase complex|trans-o-hydroxybenzylidenepyruvate hydratase-aldolase nahE|2-hydroxychromene-2-carboxylate isomerase|cis-1,2-dihydro-1,2-dihydroxynaphthalene-1, 2-dehydrogenase [NahB]4|trans-o-hydroxybenzylidenepyruvate hydratase-aldolase|1,2-dihydroxynaphthalene dioxygenase|salicylate hydroxylase|1,2-dihydroxynaphthalene dioxygenase [NahC]
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4-hydroxy-2-oxopentanoate|trans-O-hydroxybenzylidenepyruvate|2-hydroxychromene-2-carboxylate|naphthalene-1,2-diol|H2O|NAD+|acetyl-CoA|acetaldehyde|(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate|naphthalene|pyruvate|CO2|cis naphthalene dihydrodiol|salicylate|oxygen|coenzyme A|formate|2-oxopent-4-enoate|H+|catechol|NADH|salicylaldehyde
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22
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aromatic compounds degradation via β-ketoadipate
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PWY-5431
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β-ketoadipate enol-lactone hydrolase [PcaD]3|β-ketoadipate enol-lactone hydrolase|catechol 1,2-dioxygenase|β-ketoadipyl CoA thiolase|β-ketoadipate:succinyl CoA transferase|muconolactone isomerase|4-carboxymuconolactone decarboxylase [PcaC]6|protocatechuate 3,4-dioxygenase|β-ketoadipate:succinyl CoA transferase [PcaI]2[PcaJ]2|4-carboxymuconolactone decarboxylase|muconate cycloisomerase|3-carboxymuconate cycloisomerase
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3-oxoadipyl-CoA|2-carboxy-5-oxo-2,5-dihydrofuran-2-acetate|H2O|acetyl-CoA|cis,cis-muconate|3-carboxy-cis,cis-muconate|muconolactone|3-oxoadipate enol lactone|3-oxoadipate|protocatechuate|H+|succinyl-CoA|catechol|succinate|CO2|oxygen|coenzyme A
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22
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L-ascorbate biosynthesis VI (engineered pathway)
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PWY-7165
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2,5-didehydrogluconate reductase|2,5-diketo-D-gluconate reductase A|quinoprotein glucose dehydrogenase|D-gluconate dehydrogenase
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D-gluconate|NADPH|2-keto-D-gluconate|2-keto-L-gulonate|H2O|NADP+|L-ascorbate|H+|2,5-didehydro-D-gluconate|D-glucono-1,5-lactone
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22
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catechol degradation III (ortho-cleavage pathway)
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PWY-5417
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β-ketoadipate enol-lactone hydrolase [PcaD]3|β-ketoadipate enol-lactone hydrolase|catechol 1,2-dioxygenase|β-ketoadipyl CoA thiolase|β-ketoadipate:succinyl CoA transferase|muconolactone isomerase|β-ketoadipate:succinyl CoA transferase [PcaI]2[PcaJ]2|muconate cycloisomerase
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3-oxoadipyl-CoA|H2O|acetyl-CoA|cis,cis-muconate|muconolactone|3-oxoadipate enol lactone|succinyl-CoA|H+|3-oxoadipate|catechol|succinate|oxygen|coenzyme A
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21
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fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)
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PWY-6837
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2,4-dienoyl-CoA reductase [SPS19]2|delta3,5-delta2,4-dienoyl-CoA isomerase|delta3, delta2-enoyl-CoA isomerase|acyl-CoA oxidase, subunit of OPC6 acyl-CoA oxidase / OPC8 acyl-CoA oxidase / acyl-CoA oxidase|acyl-CoA oxidase|Δ3,5-Δ2,4-dienoyl-CoA isomerase|fatty-acyl coenzyme A oxidase|Δ3-Δ2 -enoyl-CoA isomerase|2,4-dienoyl-CoA reductase
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a trans-2-enoyl-CoA|NADPH|a trans-2,trans-4-dienoyl-CoA|NADP+|a trans2,cis-5-dienoyl-CoA|a cis-5-enoyl-CoA|a trans-3-enoyl-CoA|hydrogen peroxide|a trans3,cis-5-dienoyl-CoA|oxygen
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21
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leukotriene biosynthesis
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PWY66-375
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leukotriene C4 synthase|Dipeptidase 2 / LTD4 dipeptidase 2|leukotriene A4 hydrolase LTA4H|γ-glutamyltransferase 5|leukotriene C4 synthase [LTC4S]2|γ-glutamyltransferase 5 [GGT5][GGT5]|arachidonate 5-lipoxygenase|leukotriene A4 hydrolase|Dipeptidase 1 / LTE4 dipeptidase|arachidonate 5-lipoxygenase ALOX5
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H2O|glycine|leukotriene A4|glutathione|leukotriene-D4|leukotriene-C4|leukotriene B4|(5S)-HPETE|leukotriene-E4|an (γ-L-glutamyl)-L-amino acid|oxygen|arachidonate
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21
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protocatechuate degradation II (ortho-cleavage pathway)
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PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY
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β-ketoadipate enol-lactone hydrolase|β-ketoadipate enol-lactone hydrolase [PcaD]3|4-carboxymuconolactone decarboxylase [PcaC]6|3-carboxymuconate cycloisomerase|4-carboxymuconolactone decarboxylase|protocatechuate 3,4-dioxygenase
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2-carboxy-5-oxo-2,5-dihydrofuran-2-acetate|H2O|3-carboxy-cis,cis-muconate|3-oxoadipate enol lactone|protocatechuate|H+|3-oxoadipate|CO2|oxygen
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21
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cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)
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PWY-7377
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cobalt-precorrin-7 (C5)-methyltransferase|cobalt-precorrin-6A reductase|cobalt-precorrin-7 (C5)-methyltransferase cbiE|cobalt precorrin-4 (C11)-methyltransferase cbiF|precorrin-2 dehydrogenase|cobalt-precorrin 3 methyltransferase [multifunctional] cbiH60|cobalt-precorrin 5A hydrolase cbiG|cobalt-sirohydrochlorin (C20)-methyltransferase [multifunctional]|cobalt-sirohydrochlorin (C20)-methyltransferase [multifunctional] [CbiL]2|uroporphyrinogen-III (C7)-methyltransferase [multifunctional]|cobalt precorrin-4 (C11)-methyltransferase|sirohydrochlorin cobaltochelatase|cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating] [CbiT]4|cobalt-precorrin-3 (C17)-methyltransferase|cobalt-precorrin-6A synthase cbiD|cobalt-precorrin 3 methyltransferase [multifunctional]|cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]|cobalt-precorrin-8 methylmutase|cobaltochelatase|cobalt-precorrin-6A synthase|cobyrinate a,c-diamide synthase|cobalt-precorrin 5A hydrolase
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S-adenosyl-L-methionine|cobalt-precorrin-6A|L-glutamine|Co2+|H2O|NAD+|cobalt-precorrin-5B|cob(II)yrinate a,c-diamide|acetaldehyde|precorrin-2|L-glutamate|phosphate|CO2|cobalt-factor III|cobalt-precorrin-3|cobalt-precorrin-6B|precorrin-1|cobalt-precorrin-7|cobalt-sirohydrochlorin|uroporphyrinogen-III|NADH|cobalt-precorrin-4|sirohydrochlorin|cobyrinate|H+|S-adenosyl-L-homocysteine|cobalt-precorrin-8|cobalt-precorrin-5A
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20
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