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grixazone biosynthesis
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PWY-7153
|
2-amino-4,5-dihydroxy-6-one-heptanoic acid-7-phosphate synthase [GriI]10|grixazone synthase|grixazone synthase griF|3-amino-4-hydroxybenzoic acid synthase|3-amino-4-hydroxybenzoic acid reductase complex|2-amino-4,5-dihydroxy-6-one-heptanoic acid-7-phosphate synthase|3-amino-4-hydroxybenzoic acid synthase griH
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H2O|L-aspartyl-4-phosphate|NADPH|phosphate|L-aspartate|2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate|diphosphate|grixazone A|NADP+|grixazone B|CO2|N-acetyl-L-cysteine|glycerone phosphate|3-amino-4-hydroxybenzoate|L-aspartate-semialdehyde|H+|NAD+|formate|3-amino-4-hydroxybenzaldehyde|NADH|oxygen
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37
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pyruvate fermentation to acetate and lactate II
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PWY-5100
|
phosphate acetyltransferase|acetate kinase|L-lactate dehydrogenase|pyruvate:ferredoxin oxidoreductase
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acetate|NAD+|acetyl-CoA|acetyl phosphate|CO2|H+|phosphate|coenzyme A|pyruvate|NADH|(S)-lactate
|
37
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|
superpathway of purine deoxyribonucleosides degradation
|
PWY0-1297
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acetaldehyde dehydrogenase 2|aldehyde-alcohol dehydrogenase|adenosine deaminase|deoxyribose-phosphate aldolase|phosphopentomutase|purine nucleoside phosphorylase
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2-deoxy-D-ribose 5-phosphate|H2O|NAD+|acetyl-CoA|ammonium|adenine|D-glyceraldehyde 3-phosphate|hypoxanthine|acetaldehyde|2-deoxy-α-D-ribose 1-phosphate|2-deoxyadenosine|guanine|H+|phosphate|2-deoxyinosine|2-deoxyguanosine|NADH|coenzyme A
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36
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adenine and adenosine salvage III
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PWY-6609
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hypoxanthine phosphoribosyltransferase|xanthine-guanine phosphoribosyltransferase|hypoxanthine-guanine phosphoribosyltransferase|adenosine deaminase|hypoxanthine (guanine) phosphoribosyltransferase|purine nucleoside phosphorylase|xanthosine phosphorylase
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H2O|adenosine|ammonium|adenine|diphosphate|hypoxanthine|inosine|α-D-ribose-1-phosphate|H+|phosphate|5-phospho-α-D-ribose 1-diphosphate
|
36
|
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glutathione-mediated detoxification I
|
PWY-4061
|
glutathione S-transferase A1|kynurenine aminotransferase I|Maleylacetoacetate isomerase, subunit of maleylacetoacetate isomerase|glutathione S-transferase A2|γ-glutamyl hydrolase|glutathione S-transferase A heterodimer|cysteinylglycinase / cytosolic leucyl aminopeptidase|pteroyl-γ-glutamyl hydrolase|cysteine-S-conjugate N-acetyltransferase|kynurenine--oxoglutarate transaminase 3|aminopeptidase M
|
H2O|RX|a thiol|glycine|a Cys-Gly-S-conjugate|glutathione|HX|an L-cysteine-S-conjugate|acetyl-CoA|L-glutamate|H+|ammonium|a glutathione-toxin conjugate|pyruvate|coenzyme A
|
36
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glutathione-mediated detoxification II
|
PWY-6842
|
glutathione S-transferase|glutathione S-conjugate carboxypeptidase|γ-glutamyl transpeptidase|glutathione S-conjugate carboxypeptidase PCS1|cysteine-S-conjugate N-malonyl transferase|thiol S-methyltransferase|cysteine-S-conjugate C-S lyase
|
S-adenosyl-L-methionine|an N-malonyl-L-cysteine-S-conjugate|H2O|RX|a thiol|glycine|a methyl thioether|a glutathione-toxin conjugate|glutathione|HX|a Glu-Cys-S-conjugate|a Cys-Gly-S-conjugate|an L-cysteine-S-conjugate|L-glutamate|H+|ammonium|malonyl-CoA|pyruvate|S-adenosyl-L-homocysteine|coenzyme A
|
36
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glycogen degradation II
|
PWY-5941
|
glycogen debranching enzyme|phosphoglucomutase-2|phosphoglucomutase-1|glucan 1,4-α-glucosidase [SGA1]2|glycogen phosphorylase, brain isoform|glycogen phosphorylase, liver isoform|glycogen phosphorylase b|glucan 1,4-α-glucosidase|glycogen phosphorylase|glycogen phosphorylase, muscle isoform
|
phosphate|H2O|α-D-glucopyranose 1-phosphate|D-glucopyranose 6-phosphate
|
36
|
|
superpathway of erythromycin biosynthesis
|
PWY-6977
|
6-deoxyerythronolide B synthase [(EryA3)(EryA2)(EryA1)]2|dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming)|6-deoxyerythronolide B 6S-monooxygenase|dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-α-L-allose 5-epimerase eryBVII|dTDP-L-mycarosyl: erythronolide B mycarosyltransferase|dTDP-3-oxo-3,4,6-trideoxy-α-D-glucopyranose transaminase|6-deoxyerythronolide B synthase|glucose-1-phosphate thymidylyltransferase|dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-α-L-allose 5-epimerase|dTDP-4-amino-4,6-dideoxy-D-glucose transaminase|dTDP-4-amino-4,6-dideoxy-D-glucose deaminase|dTDP-glucose 4,6-dehydratase|dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase|dTDP-4-dehydro-6-deoxy-D-glucose 2,3-dehydratase|3-L-mycarosyl erythronolide B desosaminyltransferase complex|erythromycin C-12 monooxygenase|dTDP-4-dehydro-2,6-dideoxy-α-D-allose 3-C-methyltransferase|dTDP-L-mycarosyl: erythronolide B mycarosyltransferase eryBV|3-L-mycarosyl erythronolide B desosaminyltransferase complex [(EryCII)(EryCIII)]2|erythromycin C-12 monooxygenase eryK|dTDP-4-dehydro-3-methyl-2,6-dideoxy-α-L-galactose 4-ketoreductase eryBIV|6-deoxyerythronolide B 6S-monooxygenase eryF|dTDP-4-dehydro-3-methyl-2,6-dideoxy-α-L-galactose 4-ketoreductase|dTDP-4-dehydro-2,6-dideoxy-α-D-allose 3-C-methyltransferase eryBIII
|
S-adenosyl-L-methionine|dTDP-β-L-mycarose|dTDP-4-dehydro-6-deoxy-α-D-glucopyranose|NADPH|6-deoxyerythronolide B|(S)-methylmalonyl-CoA|dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose|erythromycin A|ammonium|dTDP-α-D-glucose|L-methionine|H2O|erythromycin C|NADP+|dTDP-4-dehydro-2,6-dideoxy-α-D-allose|3-α-mycarosylerythronolide B|L-glutamate|oxygen|propanoyl-CoA|CO2|5-deoxyadenosine|dTDP-D-desosamine|erythronolide B|dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-α-L-allose|erythromycin D|dTDP-viosamine|coenzyme A|dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose|dTDP-3-dehydro-4,6-deoxy-α-D-glucose|diphosphate|α-D-glucopyranose 1-phosphate|erythromycin B|H+|S-adenosyl-L-homocysteine|dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-β-L-galactose|2-oxoglutarate
|
36
|
|
superpathway of megalomicin A biosynthesis
|
PWY-7110
|
dTDP-4-dehydro-6-deoxy-D-glucose 2,3-dehydratase|dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-L-glucose 4-ketoreductase megDV|dTDP-L-megosamine:erythromycin C L-megosaminyltransferase|MegBII aldo-keo reductase|6-deoxyerythronolide B synthase [(EryA3)(EryA2)(EryA1)]2|dTDP-L-megosamine:erythromycin C L-megosaminyltransferase megDI|dTDP-4-dehydro-3-methyl-2,6-dideoxy-α-L-galactose 4-ketoreductase eryBIV|6-deoxyerythronolide B 6S-monooxygenase eryF|dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose transaminase|dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-α-L-allose 5-epimerase eryBVII|erythromycin D C-12 hydroxylase|dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-D-glucose 5-epimerase megDIV|dTDP-glucose 4,6-dehydratase|dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-L-glucose 4-ketoreductase|dTDP-L-mycarosyl: erythronolide B mycarosyltransferase eryBV|glucose-1-phosphate thymidylyltransferase|dTDP-4-dehydro-2,6-dideoxy-α-D-allose 3-C-methyltransferase eryBIII|dTDP-3-amino-4-oxo-2,3,6-trideoxy-α-D-glucose N,N-dimethyltransferase|3-L-mycarosyl erythronolide B desosaminyltransferase complex [(EryCII)(EryCIII)]2|dTDP-3-amino-4-oxo-2,3,6-trideoxy-α-D-glucose N,N-dimethyltransferase megDIII|dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-D-glucose 5-epimerase
|
S-adenosyl-L-methionine|dTDP-β-L-mycarose|dTDP-4-dehydro-6-deoxy-α-D-glucopyranose|NADPH|(S)-methylmalonyl-CoA|dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-D-glucose|dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose|6-deoxyerythronolide B|ammonium|dTDP-3-amino-4-dehydro-2,3,6-trideoxy-α-D-glucose|dTDP-α-D-glucose|dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose|L-methionine|H2O|dTDP-L-megosamine|erythromycin C|NADP+|dTDP-4-dehydro-2,6-dideoxy-α-D-allose|3-α-mycarosylerythronolide B|L-glutamate|oxygen|propanoyl-CoA|CO2|5-deoxyadenosine|dTDP-D-desosamine|erythronolide B|dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-α-L-allose|megalomicin A|erythromycin D|dTDP-viosamine|coenzyme A|dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose|dTDP-3-dehydro-4,6-deoxy-α-D-glucose|diphosphate|α-D-glucopyranose 1-phosphate|S-adenosyl-L-homocysteine|dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-α-L-glucose|H+|dTDP-4-dehydro-3-C-methyl-2,6-dideoxy-β-L-galactose|2-oxoglutarate
|
36
|
|
tetrapyrrole biosynthesis II (from glycine)
|
PWY-5189
|
uroporphyrinogen-III synthase|delta-aminolevulinic acid dehydratase|5-aminolevulinate synthase 1|5-aminolevulinic acid synthase 1|porphobilinogen deaminase|5-aminolevulinate synthase 2|porphobilinogen synthase|5-aminolevulinate syntase 2|uroporphyrinogen III synthase
|
H2O|uroporphyrinogen-III|porphobilinogen|glycine|preuroporphyrinogen|H+|succinyl-CoA|ammonium|5-aminolevulinate|CO2|coenzyme A
|
36
|