peptidoglycan biosynthesis IV (Enterococcus faecium)
|
PWY-6471
|
peptidoglycan asparagine synthase asnH|phospho-N-acetylmuramoyl-pentapeptide-transferase mraY|PBP5 pbp5|peptidoglycan asparagine synthase|UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase murG|PBP5|undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)-N-acetylglucosamine:D-aspartate ligase|undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)-N-acetylglucosamine:D-aspartate ligase aslA|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase murF
|
NADPH|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine|UDP-N-acetyl-α-D-glucosamine|ammonium|D-alanyl-D-alanine|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine|H2O|di-trans,octa-cis-undecaprenyl phosphate|UDP-N-acetyl-α-D-muramate|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine|NADP+|L-alanine|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine|L-glutamate|a peptidoglycan dimer (E. faeciums)|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine|phosphate|a peptidoglycan with D,D cross-link (E. faecium)|UDP-N-acetyl-α-D-muramoyl-L-alanine|L-lysine|undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine|phosphoenolpyruvate|di-trans,octa-cis-undecaprenyl diphosphate|D-aspartate|D-glutamate|UDP-N-acetyl-α-D-glucosamine-enolpyruvate|diphosphate|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine|D-alanine|H+
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270
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mixed acid fermentation
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FERMENTATION-PWY
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phosphate acetyltransferase / phosphate propionyltransferase|isocitrate dehydrogenase|phosphoenolpyruvate carboxylase|pyruvate kinase I|fumarase B|fumarate reductase|formate hydrogenlyase complex|pyruvate kinase II|aldehyde-alcohol dehydrogenase|acetate kinase|fumarase A|2-ketobutyrate formate-lyase / pyruvate formate-lyase 4|fumarase C|D-lactate dehydrogenase - fermentative|phosphate acetyltransferase|ethanol dehydrogenase / alcohol dehydrogenase|malate dehydrogenase|pyruvate formate-lyase / 2-ketobutyrate formate-lyase|bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase|citrate synthase
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fumarate|NADPH|acetyl phosphate|hydrogen carbonate|(R)-lactate|H2O|NAD+|acetyl-CoA|NADP+|acetaldehyde|oxaloacetate|D-threo-isocitrate|phosphate|formate|pyruvate|CO2|ethanol|acetate|citrate|phosphoenolpyruvate|(S)-malate|succinate|coenzyme A|H2|H+|cis-aconitate|2-oxoglutarate|NADH
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257
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superpathway of glycolysis and Entner-Doudoroff
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GLYCOLYSIS-E-D
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phosphoglycerate kinase|glyceraldehyde 3-phosphate dehydrogenase|pyruvate kinase I|phosphoglucose isomerase|fructose bisphosphate aldolase class I|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase|6-phosphofructokinase I|fructose bisphosphate aldolase class II|pyridoxal phosphatase / fructose 1,6-bisphosphatase|triosephosphate isomerase|phosphogluconate dehydratase|phosphogluconate dehydratase edd|fructose 1,6-bisphosphatase II|fructose-1,6-bisphosphatase I|6-phosphogluconolactonase|enolase, subunit of degradosome|phosphoenolpyruvate synthetase|multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase|6-phosphofructokinase II|glucose 6-phosphate-1-dehydrogenase|pyruvate kinase II|fructose-1,6-bisphosphatase|2,3-bisphosphoglycerate-independent phosphoglycerate mutase
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6-phospho D-glucono-1,5-lactone|H2O|D-gluconate 6-phosphate|NAD+|phosphate|3-phospho-D-glycerate|D-glucopyranose 6-phosphate|2-phospho-D-glycerate|NADP+|phosphoenolpyruvate|glycerone phosphate|β-D-fructofuranose 6-phosphate|fructose 1,6-bisphosphate|2-dehydro-3-deoxy-D-gluconate 6-phosphate|D-glyceraldehyde 3-phosphate|H+|NADPH|pyruvate|NADH|1,3-bisphospho-D-glycerate
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244
|
1-butanol autotrophic biosynthesis (engineered)
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PWY-6886
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D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase [Slr2094]4|3-hydroxybutyryl-CoA dehydrogenase|pyruvate kinase|mitochondrial trans-2-enoyl-CoA reductase|ferredoxin-NADP oxidoreductase|photosystem I|NADPH-ferredoxin oxidoreductase|3-hydroxybutyryl-CoA dehydratase|enolase|mitochondrial trans-2-enoyl-CoA reductase TER|acetyl-CoA C-acetyltransferase|aldehyde/alcohol dehydrogenase|pyruvate dehydrogenase complex|phosphoglycerate mutase
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D-xylulose 5-phosphate|NADPH|(S)-3-hydroxybutanoyl-CoA|D-sedoheptulose-1,7-bisphosphate|hν|butanoyl-CoA|crotonyl-CoA|D-ribulose 5-phosphate|H2O|NAD+|acetyl-CoA|β-D-fructofuranose 6-phosphate|1-butanol|NADP+|D-sedoheptulose 7-phosphate|acetoacetyl-CoA|phosphate|1,3-bisphospho-D-glycerate|1-butanal|CO2|D-erythrose 4-phosphate|D-glyceraldehyde 3-phosphate|phosphoenolpyruvate|oxygen|coenzyme A|3-phospho-D-glycerate|pyruvate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|glycerone phosphate|D-ribulose-1,5-bisphosphate|H+|NADH
|
238
|
superpathway of adenosine nucleotides de novo biosynthesis II
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PWY-6126
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ribonucleoside-triphosphate reductase, subunit of anaerobic nucleoside-triphosphate reductase activating system|ribonucleoside-triphosphate reductase [NrdD]2|nucleoside diphosphate kinase|ribonucleoside diphosphate reductase 1|adenylosuccinate lyase|adenylate kinase|ribonucleoside-diphosphate reductase 2|adenylosuccinate synthetase
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fumarate|H2O|L-aspartate|adenylo-succinate|H+|phosphate
|
238
|
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
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PWY-7218
|
phosphoglycerate kinase|3-hydroxybutyryl-CoA dehydrogenase|pentose-5-phosphate 3-epimerase|pyruvate kinase I|ribose-5-phosphate isomerase A|photosystem I|glyceraldehyde 3-phosphate dehydrogenase 2|β-ketothiolase|fatty acid oxidation complex, α component, subunit of aerobic fatty acid oxidation complex|fructose-1,6-bisphosphatase I|phosphoribulokinase|ribulose bisphosphate carboxylase/oxygenase|triosephosphate isomerase|fructose 1,6-bisphosphatase II|NADPH-ferredoxin oxidoreductase|enolase, subunit of degradosome|acetyl-CoA C-acetyltransferase|acyl-CoA thioesterase|D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase [Slr2094]4|transketolase|allose-6-phosphate isomerase / ribose-5-phosphate isomerase B|ribose 5-phosphate isomerase|FadJ component of anaerobic fatty acid oxidation complex|fructose bisphosphate aldolase class I|D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase|pyruvate dehydrogenase|fructose-bisphosphate aldolase / sedoheptulose-1,7-bisphosphate aldolase|hydroxyvaleryl-CoA reductase / acetoacetyl-CoA reductase|transketolase II|pyruvate kinase II|acetyl-CoA acetyltransferase|ribulose-5-phosphate 3-epimerase|thioesterase II|transketolase I|2,3-bisphosphoglycerate-independent phosphoglycerate mutase|fructose bisphosphate aldolase class II
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D-xylulose 5-phosphate|NADPH|(S)-3-hydroxybutanoyl-CoA|D-sedoheptulose-1,7-bisphosphate|(S)-3-hydroxybutanoate|hν|D-ribulose 5-phosphate|H2O|NAD+|acetyl-CoA|β-D-fructofuranose 6-phosphate|NADP+|D-sedoheptulose 7-phosphate|acetoacetyl-CoA|phosphate|1,3-bisphospho-D-glycerate|pyruvate|CO2|D-erythrose 4-phosphate|D-glyceraldehyde 3-phosphate|phosphoenolpyruvate|(R)-3-hydroxybutanoate|oxygen|coenzyme A|3-phospho-D-glycerate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|glycerone phosphate|(3R)-3-hydroxybutanoyl-CoA|D-ribulose-1,5-bisphosphate|H+|NADH
|
238
|
superpathway of glucose and xylose degradation
|
PWY-6901
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xylose isomerase|transaldolase [TalB]2|glyceraldehyde-3-phosphate dehydrogenase
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D-xylulose 5-phosphate|2-phospho-D-glycerate|NADPH|D-ribulose 5-phosphate|(R)-lactate|H2O|NAD+|D-xylulose|β-D-fructofuranose 6-phosphate|NADP+|D-sedoheptulose 7-phosphate|D-glyceraldehyde 3-phosphate|phosphate|pyruvate|CO2|D-xylopyranose|D-erythrose 4-phosphate|6-phospho D-glucono-1,5-lactone|phosphoenolpyruvate|(S)-lactate|1,3-bisphospho-D-glycerate|3-phospho-D-glycerate|D-gluconate 6-phosphate|H+|D-glucopyranose 6-phosphate|NADH
|
231
|
superpathway of adenosine nucleotides de novo biosynthesis I
|
PWY-7229
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adenylosuccinate synthase|adenylate kinase|nucleoside diphosphate kinase|ribonucleoside diphosphate reductase 1|adenylosuccinate lyase|ribonucleoside-diphosphate reductase|adenylosuccinate lyase [multifunctional]|adenylate kinase isoenzyme 5|nucleoside-diphosphate kinase 1|adenylate kinase 1|adenylosuccinate synthetase
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fumarate|H2O|L-aspartate|adenylo-succinate|H+|phosphate
|
227
|
superpathway of glyoxylate cycle and fatty acid degradation
|
PWY-561
|
aconitase|peroxisomal fatty acid β-oxidation multifunctional protein MFP2|malate dehydrogenase (NAD)|succinate dehydrogenase complex|fumarase|citrate synthase (mitochondrial)|long-chain acyl-CoA synthetase 7|peroxisomal fatty acid β-oxidation multifunctional protein AIM1|malate synthase|phosphoenolpyruvate carboxykinase (ATP)|malate dehydrogenase|long-chain acyl-CoA synthetase 6|OPC4-3-ketoacyl-CoA thiolase [multifunctional]|isocitrate lyase
|
a 2,3,4-saturated fatty acid|fumarate|H2O|a trans-2-enoyl-CoA|NAD+|acetyl-CoA|(S)-malate|citrate|diphosphate|glyoxylate|CO2|phosphoenolpyruvate|oxaloacetate|D-threo-isocitrate|hydrogen peroxide|H+|cis-aconitate|succinate|NADH|oxygen|coenzyme A
|
227
|
peptidoglycan biosynthesis V (β-lactam resistance)
|
PWY-6470
|
DdcY D-alanyl-D-alanine carboxypeptidase|peptidoglycan L,D-transpeptidase|DdcY D-alanyl-D-alanine carboxypeptidase [DdcY]2|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase murF|peptidoglycan L,D-transpeptidase ldt
|
NADPH|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine|UDP-N-acetyl-α-D-glucosamine-enolpyruvate|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine|ammonium|D-alanyl-D-alanine|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine|a peptidoglycan tetramer with L,D cross-links (L-lys-D-Asn-L-Lys)|a peptidoglycan dimer (tetrapeptide)|di-trans,octa-cis-undecaprenyl phosphate|UDP-N-acetyl-α-D-muramate|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine|NADP+|L-alanine|L-glutamate|phosphate|undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine|H2O|phosphoenolpyruvate|L-lysine|UDP-N-acetyl-α-D-muramoyl-L-alanine|di-trans,octa-cis-undecaprenyl diphosphate|D-aspartate|D-glutamate|UDP-N-acetyl-α-D-glucosamine|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine|D-alanine|H+|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine
|
221
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