superpathway of menaquinol-11 biosynthesis
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PWY-5897
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S-adenosyl-L-methionine|2-carboxy-1,4-naphthoquinol|chorismate|H2O|4-(2-carboxyphenyl)-4-oxobutyryl-CoA|isochorismate|1,4-dihydroxy-2-naphthoyl-CoA|isopentenyl diphosphate|pyruvate|S-adenosyl-L-homocysteine|H+|menaquinol-11|coenzyme A|diphosphate|CO2|(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate|2-succinylbenzoate|demethylmenaquinol-11|all-trans-undecaprenyl diphosphate|2-oxoglutarate|2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate|(2E,6E)-farnesyl diphosphate
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51
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superpathway of menaquinol-12 biosynthesis
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PWY-5898
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S-adenosyl-L-methionine|menaquinol-12|2-carboxy-1,4-naphthoquinol|chorismate|demethylmenaquinol-12|H2O|4-(2-carboxyphenyl)-4-oxobutyryl-CoA|isochorismate|1,4-dihydroxy-2-naphthoyl-CoA|all-trans-dodecaprenyl diphosphate|isopentenyl diphosphate|pyruvate|S-adenosyl-L-homocysteine|H+|coenzyme A|diphosphate|CO2|(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate|2-succinylbenzoate|2-oxoglutarate|2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate|(2E,6E)-farnesyl diphosphate
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51
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superpathway of menaquinol-13 biosynthesis
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PWY-5899
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|
S-adenosyl-L-methionine|2-carboxy-1,4-naphthoquinol|chorismate|CO2|H2O|4-(2-carboxyphenyl)-4-oxobutyryl-CoA|isochorismate|1,4-dihydroxy-2-naphthoyl-CoA|isopentenyl diphosphate|pyruvate|S-adenosyl-L-homocysteine|menaquinol-13|H+|coenzyme A|diphosphate|all-trans-tridecaprenyl diphosphate|(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate|demethylmenaquinol-13|2-succinylbenzoate|2-oxoglutarate|2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate|(2E,6E)-farnesyl diphosphate
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51
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sucrose degradation IV (sucrose phosphorylase)
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PWY-5384
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sucrose phosphorylase|phosphoglucomutase|fructokinase|glucose-6-phosphate isomerase
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sucrose|D-glucopyranose 6-phosphate|α-D-glucopyranose 1-phosphate|β-D-fructofuranose 6-phosphate|H+|phosphate|β-D-fructofuranose
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51
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crotonate fermentation (to acetate and cyclohexane carboxylate)
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PWY-7401
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6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase [Had]2|acetate-CoA ligase (ADP-forming) [AcdA]2[AcdB]2|6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase|cyclohexa-1,5-dienecarbonyl-CoA hydratase|cyclohex-1-ene-1-carbonyl-CoA dehydrogenase [SYN_02587]4|glutaryl-CoA dehydrogenase [GcdH]4|cyclohexane-1-carbonyl-CoA dehydrogenase|cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
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3-oxopimeloyl-CoA|(S)-3-hydroxybutanoyl-CoA|cyclohex-1-ene-1-carbonyl-CoA|crotonyl-CoA|glutaryl-CoA|H2O|NAD+|acetyl-CoA|cyclohex-1,5-diene-1-carbonyl-CoA|6-oxocyclohex-1-ene-1-carbonyl-CoA|acetoacetyl-CoA|phosphate|CO2|acetate|3-hydroxypimeloyl-CoA|coenzyme A|(E)-glutaconyl-CoA|cyclohexane-1-carboxylate|crotonate|cyclohexane-1-carbonyl-CoA|H+|NADH
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51
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superpathway of (R,R)-butanediol biosynthesis
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P125-PWY
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α-acetolactate decarboxylase|catabolic acetolactate synthase|α-acetolactate synthase|diacetyl reductase / (S)-acetoin reductase [(S,S)-2,3-butanediol forming]
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diacetyl|NAD+|(S)-2-acetolactate|CO2|(R)-acetoin|H+|(R,R)-2,3-butanediol|pyruvate|NADH
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51
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superpathway of cholesterol degradation I (cholesterol oxidase)
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PWY-6928
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4-hydroxy-2-oxohexanoate aldolase|3-ketosteroid-Δ1-dehydrogenase|3-oxocholest-4,24-dien-26-oyl-CoA hydratase echA19|3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase|3-ketosteroid 9α-hydroxylase complex|2-hydroxyhexa-2,4-dienoate hydratase|propanal dehydrogenase|3-oxocholest-4-en-26-oyl-CoA dehydrogenase [ChsE5]2[ChsE4]2|3-oxocholest-4-en-26-oate–CoA ligase|cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]|3-oxo-23,24-bisnorchol-4-en-17-ol-22-oyl-CoA lyase|5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA dehydrogenase|3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-monooxygenase, subunit of 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase complex|3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA hydratase|4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase|cholesterol oxidase|3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase|3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase|steroid 3-ketoacyl-CoA thiolase [FadA5]2|3-oxochol-4-en-24-oyl-CoA dehydrogenase [ChsE3]2
|
(2Z,4Z)-2-hydroxyhexa-2,4-dienoate|24-hydroxy-3-oxocholest-4-en-26-oyl-CoA|NADPH|(25S)-3-oxocholest-4-en-26-oyl-CoA|cholest-4-en-3-one|androsta-1,4-diene-3,17-dione|3-oxo-4-pregnene-20-carboxyl-CoA|NADP+|FMNH2|3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione|5-hydroxy-3-(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-ylpropanoyl-CoA|22-hydroxy-3-oxochol-4-en-24-oyl-CoA|3-(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-ylpropanoyl-CoA|3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl-3-oxopropanoyl-CoA|3,24-dioxocholest-4-en-26-oyl-CoA|H2O|NAD+|acetyl-CoA|3-oxocholest-4,24-dien-26-oyl-CoA|(25S)-3-oxocholest-4-en-26-oate|cholest-5-en-3-one|17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA|3-oxochol-4,22-dien-24-oyl-CoA|3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl-3-hydroxypropanoyl-CoA|1-propanal|propanoyl-CoA|pyruvate|3-(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-ylpropanoate|3,22-dioxochol-4-en-24-oyl-CoA|3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxylate|(2E)-3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-ylprop-2-enoyl-CoA|(25S)-26-oxocholest-4-en-3-one|hydrogen peroxide|androst-4-ene-3,17-dione|(S)-4-hydroxy-2-oxohexanoate|oxygen|coenzyme A|cholesterol|(25S)-26-hydroxycholest-4-en-3-one|3-oxo-4,17-pregnadiene-20-carboxyl-CoA|diphosphate|(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1 (10),2-dien-4-oate|3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione|9α-hydroxyandrosta-1,4-diene-3,17-dione|H+|3-oxochol-4-en-24-oyl-CoA|NADH
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51
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superpathway of cholesterol degradation II (cholesterol dehydrogenase)
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PWY-6947
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α-methylacyl-CoA racemase mcr|3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase|3-oxocholest-4-en-26-oyl-CoA dehydrogenase [ChsE5]2[ChsE4]2|3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-monooxygenase, subunit of 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase complex|3 β-hydroxysteroid dehydrogenase|3-oxocholest-4-en-26-oyl-CoA dehydrogenase|3-oxochol-4-en-24-oyl-CoA dehydrogenase [ChsE3]2|3-oxocholest-4,24-dien-26-oyl-CoA hydratase echA19|3-oxocholest-4-en-26-oate--CoA ligase fadD19|2-hydroxyhexa-2,4-dienoate hydratase|3-oxocholest-4,24-dien-26-oyl-CoA hydratase|4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase|3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase|3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase|cholest-4-en-3-one C26 monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]|steroid 3-ketoacyl-CoA thiolase|3-oxochol-4-en-24-oyl-CoA dehydrogenase|cholest-4-en-3-one C26 monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] cyp142|5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA dehydrogenase|3-oxo-23,24-bisnorchol-4-en-17-ol-22-oyl-CoA lyase|3-oxosteroid 1-dehydrogenase|3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA hydratase|3-oxocholest-4-en-26-oate--CoA ligase|cholesterol oxidase|steroid 3-ketoacyl-CoA thiolase [FadA5]2|3-ketosteroid 9α-hydroxylase|propanal dehydrogenase|3 β-hydroxysteroid dehydrogenase hsdD|cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]|4-hydroxy-2-oxohexanoate aldolase|α-methylacyl-CoA racemase
|
(2Z,4Z)-2-hydroxyhexa-2,4-dienoate|(25R)-26-oxocholest-4-en-3-one|24-hydroxy-3-oxocholest-4-en-26-oyl-CoA|NADPH|(25S)-3-oxocholest-4-en-26-oyl-CoA|cholest-4-en-3-one|3-oxo-4-pregnene-20-carboxyl-CoA|NADP+|FMNH2|3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione|5-hydroxy-3-(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-ylpropanoyl-CoA|22-hydroxy-3-oxochol-4-en-24-oyl-CoA|3-(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-ylpropanoyl-CoA|3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl-3-oxopropanoyl-CoA|3,24-dioxocholest-4-en-26-oyl-CoA|H2O|NAD+|acetyl-CoA|3-oxocholest-4,24-dien-26-oyl-CoA|(25S)-3-oxocholest-4-en-26-oate|cholest-5-en-3-one|17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA|3-oxochol-4,22-dien-24-oyl-CoA|3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl-3-hydroxypropanoyl-CoA|1-propanal|propanoyl-CoA|pyruvate|3-(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-ylpropanoate|3,22-dioxochol-4-en-24-oyl-CoA|3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxylate|(25R)-26-hydroxycholest-4-en-3-one|(2E)-3-(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-ylprop-2-enoyl-CoA|(25S)-26-oxocholest-4-en-3-one|(25R)-3-oxocholest-4-en-26-oate|androsta-1,4-diene-3,17-dione|androst-4-ene-3,17-dione|(S)-4-hydroxy-2-oxohexanoate|oxygen|coenzyme A|cholesterol|(25R)-3-oxocholest-4-en-26-oyl-CoA|(25S)-26-hydroxycholest-4-en-3-one|3-oxo-4,17-pregnadiene-20-carboxyl-CoA|diphosphate|(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1 (10),2-dien-4-oate|3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione|9α-hydroxyandrosta-1,4-diene-3,17-dione|H+|3-oxochol-4-en-24-oyl-CoA|NADH
|
51
|
purine ribonucleosides degradation
|
PWY0-1296
|
purine nucleoside phosphorylase|adenosine deaminase|phosphoglucomutase-2|xanthosine phosphorylase|phosphopentomutase
|
H2O|adenosine|ammonium|adenine|hypoxanthine|guanosine|inosine|α-D-ribose-1-phosphate|xanthosine|guanine|H+|phosphate|xanthine
|
51
|
pyruvate fermentation to butanol II (engineered)
|
PWY-6883
|
3-hydroxybutyryl-CoA dehydrogenase|mitochondrial trans-2-enoyl-CoA reductase|3-hydroxybutyryl-CoA dehydratase|ethanol dehydrogenase / alcohol dehydrogenase|aldehyde-alcohol dehydrogenase|acetyl-CoA acetyltransferase|fatty acid oxidation complex, α component, subunit of aerobic fatty acid oxidation complex|mitochondrial trans-2-enoyl-CoA reductase TER|acetyl-CoA C-acetyltransferase|FadJ component of anaerobic fatty acid oxidation complex|aldehyde/alcohol dehydrogenase
|
H2O|NAD+|acetyl-CoA|butanoyl-CoA|1-butanol|acetoacetyl-CoA|(S)-3-hydroxybutanoyl-CoA|H+|1-butanal|NADH|crotonyl-CoA|coenzyme A
|
50
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