|
superpathway of purine nucleotide salvage
|
PWY66-409
|
nucleoside diphosphate kinase|guanylate kinase|hypoxanthine-guanine phosphoribosyltransferase|adenylosuccinate lyase|ribonucleoside-diphosphate reductase|adenosine deaminase|adenylate kinase isoenzyme 5|purine nucleoside phosphorylase
|
fumarate|H2O|NAD+|adenosine|ammonium|adenine|L-glutamine|diphosphate|guanosine|L-aspartate|inosine|adenylo-succinate|α-D-ribose-1-phosphate|L-glutamate|hypoxanthine|guanine|H+|phosphate|5-phospho-α-D-ribose 1-diphosphate|NADH
|
337
|
|
superpathway of anaerobic sucrose degradation
|
PWY-7345
|
glyceraldehyde 3-phosphate dehydrogenase|sucrose synthase|NAD-dependent glyceraldehyde-3-phosphate dehydrogenase|cytosolic glucose-6-phosphate isomerase|pyruvate decarboxylase|cytoplasmic enolase|cytoplasmic 2,3-bisphosphoglycerate-independent phosphoglycerate mutase|cytosolic 6-phosphofructokinase|chloroplastic fructose-bisphosphate aldolase|UDP-sugar pyrophosphorylase|chloroplastic glyceraldehyde 3-phosphate dehydrogenase|alcohol dehydrogenase|plastidic cofactor-independent phosphoglycerate mutase|cytosolic triose phosphate isomerase|UDP-glucose pyrophosphorylase|plastidic enolase|plastidic phosphoglucose isomerase|α-phosphoglucomutase|UDP-L-arabinose pyrophosphorylase [multifunctional]|cytosolic 3-phosphoglycerate kinase|cytosolic fructose-1,6-biphosphate aldolase|cytosolic enolase|plastidic 3-phosphoglycerate kinase|fructokinase / hexokinase|plastidic pyruvate kinase|chloroplastic 6-phosphofructokinase|N-acetylglucosamine-1-phosphate uridylyltransferase|phosphoglucomutase|6-phosphofructokinase|cytosolic pyruvate kinase|fructokinase (recombinant)|fructose-1,6-bisphosphatase|cytosolic triose-phosphate isomerase|cytosolic cofactor-independent phosphoglycerate mutase|L-lactate dehydrogenase|fructokinase-Ib
|
sucrose|H2O|NAD+|β-D-fructofuranose 6-phosphate|acetaldehyde|α-D-glucopyranose 1-phosphate|D-glyceraldehyde 3-phosphate|phosphate|β-D-fructofuranose|CO2|ethanol|UDP-α-D-glucose|phosphoenolpyruvate|(S)-lactate|1,3-bisphospho-D-glycerate|3-phospho-D-glycerate|pyruvate|diphosphate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|glycerone phosphate|H+|D-glucopyranose 6-phosphate|NADH
|
325
|
|
heterolactic fermentation
|
P122-PWY
|
fructokinase|glucose-6-phosphate isomerase|phosphoketolase|phosphotransacetylase|glucose-6-phosphate 1-dehydrogenase|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase|D-lactate dehydrogenase|acetaldehyde dehydrogenase|L-lactate dehydrogenase
|
D-xylulose 5-phosphate|D-gluconate 6-phosphate|NADPH|D-ribulose 5-phosphate|(R)-lactate|H2O|NAD+|acetyl-CoA|β-D-fructofuranose 6-phosphate|NADP+|acetaldehyde|D-glyceraldehyde 3-phosphate|phosphate|1,3-bisphospho-D-glycerate|β-D-fructofuranose|CO2|ethanol|acetyl phosphate|6-phospho D-glucono-1,5-lactone|phosphoenolpyruvate|(S)-lactate|coenzyme A|3-phospho-D-glycerate|pyruvate|2-phospho-D-glycerate|H+|D-glucopyranose 6-phosphate|NADH
|
325
|
|
hexitol fermentation to lactate, formate, ethanol and acetate
|
P461-PWY
|
pyruvate kinase|NAD-dependent alcohol dehydrogenase|sorbitol-6-phosphate 2-dehydrogenase|mannitol-1-phosphate 5-dehydrogenase|enolase|pyruvate formate-lyase|NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase|L-lactate dehydrogenase
|
acetate|H2O|NAD+|acetyl-CoA|β-D-fructofuranose 6-phosphate|acetaldehyde|D-glyceraldehyde 3-phosphate|phosphate|formate|pyruvate|ethanol|acetyl phosphate|D-sorbitol 6-phosphate|phosphoenolpyruvate|D-fructose 6-phosphate|(S)-lactate|coenzyme A|D-mannitol 1-phosphate|3-phospho-D-glycerate|1,3-bisphospho-D-glycerate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|glycerone phosphate|H+|NADH
|
314
|
|
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass
|
GLYCOLYSIS-TCA-GLYOX-BYPASS
|
phosphoglycerate kinase|glyceraldehyde 3-phosphate dehydrogenase|pyruvate kinase I|succinyl-CoA synthetase|fructose bisphosphate aldolase class I|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase|6-phosphofructokinase I|fructose bisphosphate aldolase class II|phosphoglucose isomerase|triosephosphate isomerase|succinate:quinone oxidoreductase|fructose-1,6-bisphosphatase I|fumarase A|fumarase C|phosphoenolpyruvate synthetase|malate synthase A|bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase|enolase, subunit of degradosome|malate:quinone oxidoreductase|fumarase B|2-oxoglutarate dehydrogenase complex|6-phosphofructokinase II|aconitate hydratase 1|malate:quinone oxidoreductase mqo|isocitrate dehydrogenase|pyruvate dehydrogenase|fructose 1,6-bisphosphatase II|pyruvate kinase II|pyridoxal phosphatase / fructose 1,6-bisphosphatase|fructose-1,6-bisphosphatase|2,3-bisphosphoglycerate-independent phosphoglycerate mutase|isocitrate lyase|malate dehydrogenase|citrate synthase
|
fumarate|NADPH|H2O|NAD+|acetyl-CoA|β-D-fructofuranose 6-phosphate|NADP+|glyoxylate|oxaloacetate|D-threo-isocitrate|D-glyceraldehyde 3-phosphate|phosphate|1,3-bisphospho-D-glycerate|pyruvate|CO2|citrate|phosphoenolpyruvate|(S)-malate|succinate|coenzyme A|3-phospho-D-glycerate|D-glucopyranose 6-phosphate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|glycerone phosphate|H+|succinyl-CoA|cis-aconitate|2-oxoglutarate|NADH
|
308
|
|
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
|
PWY-7211
|
UMP synthase|thymidylate synthase|dihydroorotate dehydrogenase, type 2|orotate phosphoribosyltransferase|nucleoside-diphosphate kinase 1|cancer-related nucleoside-triphosphatase|deoxyuridine triphosphatase|dTMP kinase|uridylate kinase|nucleoside diphosphate kinase|dihydroorotase|carbamoyl phosphate synthetase|nucleoside-triphosphatase|nucleoside triphosphate pyrophosphohydrolase|pyrimidine deoxynucleoside triphosphate pyrophosphohydrolase|dihydroorotate dehydrogenase, type 2 pyrD|CTP synthase|CAD protein|thymidylate kinase|ribonucleoside-diphosphate reductase|aspartate carbamoyltransferase|apyrase|UMP kinase|ribonucleoside diphosphate reductase 1|dihydrofolate reductase/thymidylate synthase|UMP/CMP kinase|aspartate transcarbamylase
|
carbamoyl phosphate|H2O|a 7,8-dihydrofolate|L-glutamine|hydrogen carbonate|diphosphate|L-aspartate|orotate|L-glutamate|(S)-dihydroorotate|H+|phosphate|5-phospho-α-D-ribose 1-diphosphate|a 5,10-methylene-tetrahydrofolate|CO2|orotidine 5-phosphate|N-carbamoyl-L-aspartate
|
304
|
|
superpathway of chorismate metabolism
|
ALL-CHORISMATE-PWY
|
GTP cyclohydrolase I|bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase|tryptophan synthase, α subunit|tyrosine aminotransferase|1,4-dihydroxy-2-naphthoyl-CoA thioesterase|shikimate dehydrogenase / quinate dehydrogenase|bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase|2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase|shikimate dehydrogenase / quinate dehydrogenase [YdiB]2|o-succinylbenzoate-CoA ligase|dihydrofolate reductase|tryptophan synthase, β subunit dimer|bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase [UbiG]2|anthranilate synthase component II|o-succinylbenzoate synthase|chorismate lyase|branched-chain amino-acid aminotransferase|aspartate aminotransferase, PLP-dependent|2-octaprenylphenol hydroxylase|isochorismate synthase 2|dihydroneopterin triphosphate pyrophosphohydrolase|dihydroneopterin aldolase|3-dehydroquinate dehydratase|2-octaprenyl-6-methoxyphenol hydroxylase ubiH|holo-[acyl carrier protein] synthase 2|octaprenyl diphosphate synthase|3-dehydroquinate synthase|3-octaprenyl-4-hydroxybenzoate carboxy-lyase [UbiD]6|chorismate mutase / prephenate dehydratase|4-hydroxybenzoate octaprenyltransferase|3-octaprenyl-4-hydroxybenzoate carboxy-lyase|chorismate mutase / prephenate dehydrogenase|dihydromonapterin reductase / dihydrofolate reductase|(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase|1,4-dihydroxy-2-naphthoate octaprenyltransferase|2-octaprenyl-6-methoxyphenol hydroxylase|shikimate kinase II|chorismate synthase|1,4-dihydroxy-2-naphthoyl-CoA synthase|holo-[acyl-carrier-protein] synthase|anthranilate synthase|shikimate dehydrogenase|3-phosphoshikimate-1-carboxyvinyltransferase|4-amino-4-deoxychorismate synthase, subunit of para-aminobenzoate synthase multi-enzyme complex|holo-EntB dimer, subunit of enterobactin synthase|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase ubiF|bifunctional folylpolyglutamate synthetase / dihydrofolate synthetase|1,4-dihydroxy-2-naphthoate octaprenyltransferase menA|2-octaprenylphenol hydroxylase ubiI|isochorismate synthase 1|bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase ubiE|indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase|2,3-dihydroxybenzoate-AMP ligase, subunit of enterobactin synthase|phosphopantetheinyl transferase, subunit of enterobactin synthase|2-dehydro-3-deoxyphosphoheptonate aldolase|aminodeoxychorismate lyase, subunit of para-aminobenzoate synthase multi-enzyme complex|6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase|2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase|dihydropteroate synthase|holo [EntF peptidyl-carrier protein], subunit of enterobactin synthase
|
S-adenosyl-L-methionine|3-demethylubiquinol-8|NADPH|1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate|2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol|2-carboxy-1,4-naphthoquinol|L-glutamine|ubiquinol-8|shikimate 3-phosphate|6-(hydroxymethyl)-7,8-dihydropterin|4-amino-4-deoxychorismate|chorismate|(7,8-dihydropterin-6-yl)methyl diphosphate|7,8-dihydroneopterin|menaquinol-8|(2E,6E)-farnesyl diphosphate|1,4-dihydroxy-2-naphthoyl-CoA|3-(all-trans-octaprenyl)benzene-1,2-diol|a 7,8-dihydrofolate|6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol|adenosine 3,5-bisphosphate|H2O|NAD+|4-(2-carboxyphenyl)-4-oxobutyryl-CoA|indole|isochorismate|5-enolpyruvoyl-shikimate 3-phosphate|NADP+|7,8-dihydroneopterin 3-phosphate|4-hydroxyphenylpyruvate|isopentenyl diphosphate|glycolaldehyde|L-glutamate|4-hydroxybenzoate|L-tryptophan|D-glyceraldehyde 3-phosphate|7,8-dihydroneopterin 3-triphosphate|phosphate|5-phospho-α-D-ribose 1-diphosphate|formate|pyruvate|CO2|L-phenylalanine|2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate|D-erythrose 4-phosphate|L-serine|L-tyrosine|2-methoxy-6-(all-trans-octaprenyl)phenol|shikimate|3-dehydroshikimate|a tetrahydrofolate|phosphoenolpyruvate|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate|prephenate|2-succinylbenzoate|all-trans-octaprenyl diphosphate|7,8-dihydrofolate monoglutamate|3-octaprenyl-4-hydroxybenzoate|(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate|L-seryl-adenylate|oxygen|coenzyme A|3-deoxy-D-arabino-heptulosonate 7-phosphate|anthranilate|demethylmenaquinol-8|diphosphate|2,3-dihydroxybenzoate|7,8-dihydropteroate|4-aminobenzoate|2-oxo-3-phenylpropanoate|(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate|2-octaprenylphenol|3-dehydroquinate|H+|S-adenosyl-L-homocysteine|2-oxoglutarate|NADH|enterobactin|2,3-dihydroxybenzoyl adenylate
|
290
|
|
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I
|
P4-PWY
|
3-phosphoserine aminotransferase [multifunctional]|homoserine O-succinyltransferase [MetA]2|diaminopimelate decarboxylase|cobalamin-independent homocysteine transmethylase|tetrahydrodipicolinate succinylase|tetrahydrodipicolinate succinylase [DapD]2|O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase|aspartate aminotransferase, PLP-dependent|cobalamin-dependent methionine synthase|4-hydroxy-tetrahydrodipicolinate reductase|bifunctional β-cystathionase, PLP-dependent and regulator of maltose regulon|diaminopimelate epimerase|4-hydroxy-tetrahydrodipicolinate synthase|aspartate kinase III|homoserine O-succinyltransferase|aspartate kinase / homoserine dehydrogenase|O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase [MetB]4|N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase|homoserine kinase|aspartate semialdehyde dehydrogenase|N-succinyl-L-diaminopimelate desuccinylase|cystathionine-β-lyase / L-cysteine desulfhydrase|threonine synthase
|
NADPH|L,L-diaminopimelate|N-succinyl-2-amino-6-ketopimelate|L-cysteine|H2O|meso-diaminopimelate|L-homocysteine|NADP+|O-succinyl-L-homoserine|oxaloacetate|L-glutamate|L-homoserine|phosphate|pyruvate|CO2|L-cystathionine|2-aminoprop-2-enoate|N5-methyl--tetrahydropteroyl tri-L-glutamate|L-methionine|a tetrahydrofolate|L-aspartyl-4-phosphate|tetrahydropteroyl tri-L-glutamate|L-lysine|L-threonine|an N5-methyl-tetrahydrofolate|succinate|coenzyme A|N-succinyl-L,L-2,6-diaminopimelate|L-aspartate-semialdehyde|L-aspartate|(S)-2,3,4,5-tetrahydrodipicolinate|O-phospho-L-homoserine|H+|succinyl-CoA|2-oxoglutarate|(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
|
290
|
|
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle
|
PWY-5464
|
glyceraldehyde 3-phosphate dehydrogenase|NAD-dependent glyceraldehyde-3-phosphate dehydrogenase|succinate dehydrogenase complex|fumarase|citrate synthase (mitochondrial)|cytoplasmic enolase|succinyl-CoA synthetase|cytoplasmic 2,3-bisphosphoglycerate-independent phosphoglycerate mutase|diphosphate:fructose-6-phosphate 1-phosphotransferase|cytosolic 6-phosphofructokinase|cytosolic triose phosphate isomerase|enolase|cytosolic 3-phosphoglycerate kinase|cytosolic fructose-bisphosphate aldolase|cytosolic fructose-1,6-biphosphate aldolase|malate dehydrogenase (NAD)|cytosolic enolase|cytosolic triosephosphate isomerase|succinate dehydrogenase|NAD+-dependent isocitrate dehydrogenase|6-phosphofructokinase|cytosolic glyceraldehyde 3-phosphate dehydrogenase|aconitase|malate dehydrogenase|diphosphate—fructose-6-phosphate 1-phosphotransferase|cytosolic pyruvate kinase|cytosolic fructose-1,6-bisphosphate aldolase|cytosolic triose-phosphate isomerase|cytosolic cofactor-independent phosphoglycerate mutase|cytosolic NADP-dependent glyceraldehyde-3-phosphate dehydrogenase|pyruvate dehydrogenase complex
|
fumarate|NADPH|a pyruvate dehydrogenase E2 protein N6-S-acetyldihydrolipoyl-L-lysine|a pyruvate dehydrogenase E2 protein N6-dihydrolipoyl-L-lysine|H2O|NAD+|acetyl-CoA|β-D-fructofuranose 6-phosphate|NADP+|oxaloacetate|D-threo-isocitrate|D-glyceraldehyde 3-phosphate|phosphate|1,3-bisphospho-D-glycerate|pyruvate|CO2|citrate|phosphoenolpyruvate|a pyruvate dehydrogenase E2 protein N6-lipoyl-L-lysine|(S)-malate|succinate|coenzyme A|3-phospho-D-glycerate|diphosphate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|glycerone phosphate|H+|succinyl-CoA|cis-aconitate|2-oxoglutarate|NADH
|
272
|
|
peptidoglycan biosynthesis II (staphylococci)
|
PWY-5265
|
phospho-N-acetylmuramoyl-pentapeptide-transferase|PBP3|UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase|monofunctional peptidoglycan glycosyltransferase|N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(glycine)3-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine transferase [FemB]2|N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(glycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine transferase [FemA]2|N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine transferase femX|UDP-N-acetylenolpyruvoylglucosamine reductase|UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase|PBP1|N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(glycine)3-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine transferase|PBP2|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase murF|N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine transferase|UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase|phospho-N-acetylmuramoyl-pentapeptide-transferase mraY|glutamate racemase|UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase|UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase murG|PBP4|N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(glycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine transferase|D-alanine:D-alanine ligase|peptidoglycan glutamate amidase|UDP-N-acetylmuramoyl--L-alanine ligase
|
NADPH|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(glycyl)3-D-alanyl-D-alanine|UDP-N-acetyl-α-D-glucosamine-enolpyruvate|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine|a peptidoglycan with D,D cross-link (S. aureus)|ammonium|D-alanyl-D-alanine|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine|H2O|di-trans,octa-cis-undecaprenyl phosphate|UDP-N-acetyl-α-D-muramate|D-glutamate|NADP+|L-alanine|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine|L-glutamate|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(glycyl)5-D-alanyl-D-alanine|phosphate|phosphoenolpyruvate|L-lysine|undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine|UDP-N-acetyl-α-D-muramoyl-L-alanine|di-trans,octa-cis-undecaprenyl diphosphate|UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine|UDP-N-acetyl-α-D-glucosamine|a peptidoglycan dimer (S. aureus)|ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine|D-alanine|H+
|
270
|