guanosine ribonucleotides de novo biosynthesis
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PWY-7221
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nucleoside diphosphate kinase|guanylate kinase|GMP synthetase|IMP dehydrogenase
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H2O|NAD+|diphosphate|NADH|L-glutamate|H+|L-glutamine
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57
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mevalonate pathway II (archaea)
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PWY-6174
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phosphomevalonate decarboxylase mvaD|phosphomevalonate decarboxylase|acetyl-CoA C-acetyltransferase|isopentenyl-diphosphate δ-isomerase|mevalonate kinase|isopentenyl phosphate kinase|3-hydroxy-3-methylglutaryl-coenzyme A reductase
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H2O|isopentenyl phosphate|NADPH|dimethylallyl diphosphate|acetyl-CoA|(R)-mevalonate 5-phosphate|acetoacetyl-CoA|NADP+|isopentenyl diphosphate|H+|phosphate|(R)-mevalonate|CO2|(S)-3-hydroxy-3-methylglutaryl-CoA|coenzyme A
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57
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superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis
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PWY-7323
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GDP-D-mannose 4,6-dehydratase|GDP-4-dehydro-6-deoxy-α-D-mannose 3-dehydratase [multifunctional]|GDP-α-D-mannose 4,6-dehydratase|GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase|GDP-L-colitose synthase [ColC]2|GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase [RfbE]4|mannose-1-phosphate guanylyltransferase|phosphomannomutase|GDP-4-keto-6-deoxy-D-mannose reductase|GDP-4-dehydro-6-deoxy-α-D-mannose 3-dehydratase [multifunctional] [ColD]2|phosphomannose isomerase / GDP-D-mannose pyrophosphorylase|GDP-fucose synthase|GDP-mannose 4,6-dehydratase|GDP-4-keto-6-deoxy-D-mannose reductase tld|phosphoglucose isomerase|GDP-L-colitose synthase|mannose-6-phosphate isomerase
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NADPH|ammonium|H2O|GDP-α-D-perosamine|GDP-4-dehydro-6-deoxy-α-D-mannose|β-D-fructofuranose 6-phosphate|NADP+|GDP-6-deoxy-α-D-talose|L-glutamate|GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane|GDP-α-D-rhamnose|2-oxoglutarate|D-mannopyranose 6-phosphate|α-D-mannose 1-phosphate|GDP-β-L-colitose|GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran|GDP-β-L-fucose|GDP-4-dehydro-3,6-dideoxy-α-D-mannose|diphosphate|GDP-α-D-mannose|H+|D-glucopyranose 6-phosphate
|
57
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thiamine formation from pyrithiamine and oxythiamine (yeast)
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PWY-7357
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HMP/HMP-P kinase and thiaminase II|HMP/HMP-P kinase and thiaminase II [(THI20)2]2|hydroxymethylpyrimidine phosphate (HMP-P) kinase [multifunctional]|TMP diphosphorylase/hydroxyethylthiazole kinase
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4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine|H2O|2-(2-methylpyridin-3-yl)ethanol|5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone|4-methyl-5-(2-phosphooxyethyl)thiazole|diphosphate|5-(2-hydroxyethyl)-4-methylthiazole|thiamine phosphate|H+|4-amino-2-methyl-5-pyrimidinemethanol|pyrithiamine|4-amino-2-methyl-5-(diphosphomethyl)pyrimidine|oxythiamine
|
57
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1,5-anhydrofructose degradation
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PWY-6992
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1,5-anhydro-D-fructose reductase|1,5-anhydro-D-fructose reductase afr
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H2O|1,5-anhydro-D-mannitol|1,5-anhydro-D-fructose|β-D-fructofuranose 6-phosphate|D-mannopyranose 6-phosphate|H+|D-mannopyranose|D-glucopyranose 6-phosphate|oxygen
|
56
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GDP-mannose biosynthesis
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PWY-5659
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mannose-1-phosphate guanylyltransferase|glucose-6-phosphate isomerase|GDP-D-mannose pyrophosphorylase|GDP-D-mannose pyrophosphorylase / phosphomannose isomerase|phosphomannose mutase|phosphomannomutase|cytosolic glucose-6-phosphate isomerase|phosphomannose isomerase / GDP-D-mannose pyrophosphorylase|plastidic phosphoglucose isomerase|phosphoglucose isomerase|GDP-D-glucose pyrophosphorylase / GDP-D-mannose pyrophosphorylase|phosphomannose isomerase|mannose-6-phosphate isomerase
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β-D-fructofuranose 6-phosphate|diphosphate|D-mannopyranose 6-phosphate|GDP-α-D-mannose|H+|D-glucopyranose 6-phosphate|α-D-mannose 1-phosphate
|
56
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4-aminobutanoate degradation V
|
PWY-5022
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4-hydroxybutyrate CoA-transferase|4-hydroxybutyrate dehydrogenase|vinylacetyl-CoA-Δ-isomerase / 4-hydroxybutyryl-CoA dehydratase
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acetate|NAD+|acetyl-CoA|succinate semialdehyde|butanoate|2-oxoglutarate|H2O|4-hydroxybutanoate|4-hydroxybutanoyl-CoA|L-glutamate|H+|ammonium|4-aminobutanoate|butanoyl-CoA|NADH|crotonyl-CoA
|
56
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pyridine nucleotide cycling (plants)
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PWY-5381
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NAD pyrophosphatase|NMN nucleosidase|nicotinate mononucleotide adenylyltransferase|nicotinamidase|nicotinate phosphoribosyltransferase|ribonucleoside hydrolase (pyrimidine-specific) URH1|nicotinamide riboside kinase NRK1|NAD synthetase (glutamine dependent)|NaMN nucleosidase
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D-ribofuranose 5-phosphate|H2O|β-D-ribosylnicotinate|NAD+|1-(β-D ribofuranosyl)nicotinamide|nicotinamide|L-glutamine|H+|nicotinate|nicotinate adenine dinucleotide|β-nicotinamide D-ribonucleotide|L-glutamate|phosphate|ammonium|5-phospho-α-D-ribose 1-diphosphate|D-ribulose 1-phosphate|diphosphate|D-ribofuranose|β-nicotinate D-ribonucleotide
|
55
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mevalonate pathway III (archaea)
|
PWY-7524
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mevalonate-3-phosphate-5-kinase|mevalonate-3-phosphate-5-kinase Ta0762|mevalonate-3-kinase Ta1305|isopentenyl phosphate kinase|mevalonate-3-kinase
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H2O|isopentenyl phosphate|NADPH|dimethylallyl diphosphate|acetyl-CoA|acetoacetyl-CoA|(R)-mevalonate-3,5-bisphosphate|NADP+|isopentenyl diphosphate|H+|phosphate|(R)-mevalonate|(R)-mevalonate 3-phosphate|CO2|(S)-3-hydroxy-3-methylglutaryl-CoA|coenzyme A
|
55
|
NAD salvage pathway I
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PYRIDNUCSAL-PWY
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NAD pyrophosphatase|nicotinamide mononucleotide adenylyltransferase [multifunctional]|NMN nucleosidase|nicotinate-mononucleotide adenylyltransferase|nicotinamidase|nicotinamidase / pyrazinamidase|nicotinate phosphoribosyltransferase|NAD synthetase, NH3-dependent|nicotinate nucleotide adenylyltransferase|glutamine-dependent NAD synthase|NADH pyrophosphatase 1|nicotinate phosphoribosyl transferase
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D-ribofuranose 5-phosphate|H2O|β-nicotinamide D-ribonucleotide|NAD+|nicotinamide|L-glutamine|H+|nicotinate|nicotinate adenine dinucleotide|L-glutamate|phosphate|ammonium|5-phospho-α-D-ribose 1-diphosphate|diphosphate|β-nicotinate D-ribonucleotide
|
55
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