|
L-alanine fermentation to propanoate and acetate
|
PROPFERM-PWY
|
lactyl-CoA dehydratase|pyruvate-ferredoxin oxidoreductase|acryloyl-CoA reductase|alanine aminotransferase|phosphotransacetylase|D-lactate dehydrogenase|acetate kinase|glutamate dehydrogenase|propionate CoA-transferase / lactate CoA-transferase|acryloyl-CoA reductase [(AcrC)2(AcrA)(AcrB)]4|propanoyl-CoA transferase
|
acetyl phosphate|(R)-lactate|acetate|NAD+|(R)-lactoyl-CoA|acetyl-CoA|ammonium|2-oxoglutarate|H2O|L-alanine|CO2|acryloyl-CoA|L-glutamate|H+|phosphate|propanoate|pyruvate|NADH|propanoyl-CoA|coenzyme A
|
60
|
|
pyrimidine deoxyribonucleosides salvage
|
PWY-7199
|
dihydrofolate reductase / thymidylate synthase|deoxycytidine kinase|cytidine/deoxycytidine deaminase|thymidylate synthase|thymidine kinase|cytidine deaminase|dihydrofolate reductase/thymidylate synthase|deoxynucleoside kinase|deoxyadenosine/deoxycytidine kinase|thymidine kinase 1b|thymidine kinase 2|thymidine kinase 1|thymidine kinase 1a
|
2-deoxyuridine|H2O|a nucleoside diphosphate|thymidine|H+|ammonium|a 5,10-methylene-tetrahydrofolate|a 7,8-dihydrofolate|2-deoxycytidine
|
60
|
|
docosahexaenoate biosynthesis III (6-desaturase, mammals)
|
PWY-7606
|
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial|3-oxoacyl-[acyl-carrier-protein] reductase OAR1|peroxisomal multifunctional enzyme type 2|polyunsaturated long-chain fatty acid elongase 2|peroxisomal bifunctional enzyme|acyl-CoA 4/6/8-desaturase FADS2|polyunsaturated long-chain fatty acid elongase 5|peroxisomal acyl-coenzyme A oxidase 1|mitochondrial enoyl-CoA hydratase|3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit|acyl-CoA 4/6/8-desaturase, subunit of acyl-CoA 6-desaturase complex|polyunsaturated long-chain fatty acid elongase 2 ELOVL2
|
(5Z,8Z,11Z,14Z,17Z)-3R-hydroxy-docosapentaenoyl-CoA|NADPH|(3R)-hydroxy-tetracosapentaenoyl-CoA|hydrogen peroxide|(3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA|(2Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA|3-oxo-tetracosapentaenoyl-CoA|H2O|NAD+|acetyl-CoA|(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA|NADP+|(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA|CO2|docosahexaenoyl-CoA|3-oxo-docosapentaenoyl-CoA|malonyl-CoA|(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA|oxygen|coenzyme A|3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA|NADH|H+|(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA|icosapentaenoyl-CoA|docosapentaenoyl-CoA
|
60
|
|
methyl ketone biosynthesis (engineered)
|
PWY-7007
|
3-oxoacyl-CoA hydrolase|methylketone synthase 1 MKS1|fatty acid oxidation complex, α component, subunit of aerobic fatty acid oxidation complex|thioesterase II|methylketone synthase 1|FadJ component of anaerobic fatty acid oxidation complex|acyl-CoA thioesterase|acyl coA dehydrogenase
|
H2O|a trans-2-enoyl-CoA|NAD+|diphosphate|hydrogen peroxide|CO2|a methyl ketone|a carboxylate|H+|NADH|oxygen|coenzyme A
|
60
|
|
purine nucleotides degradation II (aerobic)
|
PWY-6353
|
xanthine oxidase|xanthine dehydrogenase|alkaline phosphatase|purine nucleotidase|IMP dehydrogenase|adenosine deaminase|purine nucleoside phosphorylase|guanine deaminase|guanosine phosphorylase|xanthosine phosphorylase|xanthine oxidoreductase
|
H2O|NAD+|adenosine|ammonium|urate|guanosine|hypoxanthine|inosine|α-D-ribose-1-phosphate|xanthosine|guanine|H+|phosphate|xanthine|NADH
|
59
|
|
superpathway of bacteriochlorophyll a biosynthesis
|
PWY-5529
|
chlorophyllide a hydratase bchF|5-aminolevulinate synthase 2|3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)|chlorophyllide a hydratase|uroporphyrinogen III synthase|chlorophyllide a reductase|magnesium chelatase|bacteriochlorophyll a synthase|porphobilinogen deaminase|bacteriochlorophyllide a dehydrogenase|5-aminolevulinate synthase 1|geranylgeranyl-bacteriochlorophyll a reductase bchP|bacteriochlorophyllide a dehydrogenase bchC|anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase|coproporphyrinogen dehydrogenase|light-independent protochlorophyllide reductase|bacteriochlorophyll a synthase bchG|uroporphyrinogen decarboxylase|geranylgeranyl-bacteriochlorophyll a reductase|magnesium protoporphyrin IX methyltransferase|protoporphyrinogen oxidase [HemG]4|porphobilinogen synthase
|
coproporphyrinogen III|S-adenosyl-L-methionine|NADPH|3-devinyl-3-(1-hydroxyethyl)-chlorophyllide a|glycine|bacteriochlorophyll a|3-deacetyl-3-vinyl bacteriochlorophyllide a|3,8-divinyl protochlorophyllide a|3,8-divinyl chlorophyllide a|geranylgeranyl diphosphate|magnesium-protoporphyrin IX 13-monomethyl ester|ammonium|L-methionine|H2O|uroporphyrinogen-III|NADP+|protoporphyrinogen IX|phyta-2,10,14-trienyl bacteriochlorophyllide a|phosphate|Mg-protoporphyrin|CO2|5-deoxyadenosine|Mg2+|preuroporphyrinogen|3-acetyl-3-devinyl-chlorophyllide a|chlorophyllide a|bacteriochlorophyllide a|geranylgeranyl bacteriochlorophyllide a|NAD+|protoporphyrin IX|coenzyme A|131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester|phyta-2,14-dienyl bacteriochlorophyllide a|porphobilinogen|diphosphate|S-adenosyl-L-homocysteine|131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester|H+|succinyl-CoA|3-deacetyl-3-(1-hydroxyethyl)-bacteriochlorophyllide a|5-aminolevulinate|NADH
|
59
|
|
suberin monomers biosynthesis
|
PWY-1121
|
ω-hydroxy fatty acid ω-alcohol dehydrogenase|4-coumarate coenzyme A ligase 1|long-chain acyl-CoA synthetase 3|4-coumarate coenzyme A ligase 2|4-coumarate coenzyme A ligase 3|ω-hydroxyacid dehydrogenase|cinnamate 4-hydroxylase ATC4H|caffeoyl-CoA O-methyltransferase|very-long-chain fatty acid ω-hydroxylase|cinnamate 4-hydroxylase|caffeoyl-CoA O-methyltransferase [multifunctional]|tyramine hydroxycinnamoyltransferase|16-hydroxypalmitoyl-CoA synthetase|long-chain acyl-CoA synthetase 8|tyramine N-hydroxycinnamoyltransferase|lauroyl-CoA thioesterase [multifunctional]|long-chain fatty acid ω-hydroxylase|very-long-chain fatty acid ω-hydroxylase CYP86B1|phenylalanine ammonia lyase
|
S-adenosyl-L-methionine|NADPH|trans-cinnamate|ammonium|N-feruloyltyramine|18-hydroxyoleate|H2O|docosanoyl-CoA|palmitate|trans-caffeoyl-CoA|feruloyl-CoA|NADP+|trans-caffeate|22-carboxy-docosanoyl-CoA|22-oxo-docosanoyl-CoA|tyramine|ferulate|S-adenosyl-L-homocysteine|L-phenylalanine|oleoyl-CoA|4-coumarate|16-hydroxypalmitate|ω-carboxy-(9Z)-octadec-9-enoyl-CoA|22-hydroxy-docosanoyl-CoA|18-oxo-oleate|oxygen|coenzyme A|α,ω-9Z-octadecenedioate|palmitoyl-CoA|diphosphate|16-hydroxypalmitoyl-CoA|oleate|H+
|
59
|
|
anaerobic energy metabolism (invertebrates, mitochondrial)
|
PWY-7384
|
methylmalonyl-CoA mutase|propionyl-CoA:succinate CoA transferase|fumarate reductase complex [D78157][D78158][AB008568][D30650]|succinyl-CoA:acetate CoA-transferase|fumarase|fumarate reductase complex|propionyl-CoA carboxylase|succinyl-CoA synthetase|NAD+-dependent malic enzyme, mitochondrial|pyruvate dehydrogenase complex|methylmalonyl-CoA epimerase
|
(R)-methylmalonyl-CoA|fumarate|acetate|NAD+|acetyl-CoA|hydrogen carbonate|(S)-methylmalonyl-CoA|succinate|(S)-malate|H2O|CO2|H+|succinyl-CoA|phosphate|propanoate|pyruvate|NADH|propanoyl-CoA|coenzyme A
|
59
|
|
toluene degradation VI (anaerobic)
|
PWY-5184
|
benzoylsuccinyl-CoA thiolase|3-hydroxyacyl-CoA dehydrogenase|6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase|6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase [Had]2|benzoylsuccinyl-CoA thiolase [BbsB]|benzylsuccinyl-CoA dehydrogenase [BbsG]45|succinyl-CoA:benzylsuccinate CoA-transferase|phenylitaconyl-CoA hydratase [BbsH]|benzoyl-CoA reductase|3-hydroxyacyl-CoA dehydrogenase [BbsC][BbsD]|benzylsuccinate synthase|benzylsuccinyl-CoA dehydrogenase|glutaryl-CoA dehydrogenase [GcdH]4|cyclohexa-1,5-diene-1-carboxyl-CoA hydratase|succinyl-CoA:benzylsuccinate CoA-transferase [BbsE]2[BbsF]2|β-oxoacyl-CoA hydrolase|phenylitaconyl-CoA hydratase
|
fumarate|3-oxopimeloyl-CoA|(E)-2-benzylidenesuccinyl-CoA|benzoyl-CoA|(S)-3-hydroxybutanoyl-CoA|(R)-benzylsuccinyl-CoA|crotonyl-CoA|glutaryl-CoA|H2O|NAD+|acetyl-CoA|cyclohex-1,5-diene-1-carbonyl-CoA|6-oxocyclohex-1-ene-1-carbonyl-CoA|acetoacetyl-CoA|phosphate|coenzyme A|CO2|3-hydroxypimeloyl-CoA|succinate|(R)-2-benzylsuccinate|(E)-glutaconyl-CoA|2-carboxymethyl-3-hydroxyphenylpropanoyl-CoA|H+|succinyl-CoA|toluene|benzoylsuccinyl-CoA|NADH
|
58
|
|
unsaturated, even numbered fatty acid β-oxidation
|
PWY-5138
|
very-long-chain 3-hydroxyacyl-CoA dehydratase|MFP a|multifunctional protein MFP III|multifunctional protein MFP II|delta3, delta2-enoyl-CoA isomerase|multifunctional protein MFP I|delta-3, delta2-enoyl-CoA isomerase|peroxisomal fatty acid β-oxidation multifunctional protein AIM1|2,4-dienoyl-CoA reductase
|
H2O|a trans-2-enoyl-CoA|NADPH|NADP+|a 2-trans-4-cis-dienoyl-CoA|a trans-3-enoyl-CoA|H+
|
58
|