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glyoxylate cycle
|
GLYOXYLATE-BYPASS
|
aconitate hydratase 1|aconitase|isocitrate lyase|malate dehydrogenase (NAD)|citrate synthase (mitochondrial)|malate synthase|malate synthase A|malate dehydrogenase|bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase|citrate synthase
|
H2O|NAD+|acetyl-CoA|(S)-malate|citrate|glyoxylate|oxaloacetate|D-threo-isocitrate|H+|cis-aconitate|succinate|NADH|coenzyme A
|
62
|
|
UDP-sugars interconversion
|
PWY-5114
|
UDP-glucuronate decarboxylase|UDP-D-xylose 4-epimerase|alcohol dehydrogenase / UDP-glucose dehydrogenase|UDP-D-apiose synthase / UDP-D-xylose synthase|UDP-glucose 4-epimerase|UDP-D-xylose synthase / UDP-D-apiose synthase|UDP-glucose 4,6-dehydratase|UDP-glucose dehydrogenase|UDP-D-glucuronic acid 4-epimerase|nucleotide rhamnose synthase|UDP-galactose 4-epimerase
|
UDP-β-L-rhamnose|H2O|NADPH|UDP-D-apiose|UDP-α-D-galactose|UDP-α-D-glucose|UDP-4-dehydro-6-deoxy-D-glucose|NADP+|CO2|UDP-α-D-xylose|H+|UDP-α-D-galacturonate|NAD+|NADH|UDP-β-L-arabinopyranose|UDP-α-D-glucuronate
|
61
|
|
L-isoleucine biosynthesis II
|
PWY-5101
|
branched-chain-amino-acid aminotransferase|(R)-citramalate synthase|β-isopropylmalate dehydrogenase|acetohydroxy acid isomeroreductase|ketol-acid reductoisomerase|3-methylmalate dehydrogenase / 3-isopropylmalate dehydrogenase|dihydroxy-acid dehydratase|acetohydroxy-acid synthase|dihydroxy acid dehydratase|isopropylmalate isomerase|branched-chain amino acid aminotransferase
|
citraconate|H2O|L-isoleucine|NAD+|acetyl-CoA|2-oxoglutarate|(2R,3S)-3-methylmalate|CO2|(R)-2,3-dihydroxy-3-methylpentanoate|L-glutamate|(R)-citramalate|H+|2-oxobutanoate|(S)-3-methyl-2-oxopentanoate|pyruvate|NADH|(S)-2-aceto-2-hydroxybutanoate|coenzyme A
|
61
|
|
thiazole biosynthesis I (facultative anaerobic bacteria)
|
PWY-6892
|
2-iminoacetate synthase, subunit of thiazole synthase|cysteine desulfurase|L-cysteine desulfurase|ThiS adenylyltransferase|cysteine desulfurase [IscS]2|ThiI|1-deoxyxylulose-5-phosphate synthase|1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase, subunit of thiazole synthase
|
S-adenosyl-L-methionine|L-cysteine|H2O|NADPH|2-iminoacetate|L-methionine|an L-cysteine desulfurase L-cysteine persulfide|diphosphate|D-glyceraldehyde 3-phosphate|NADP+|L-alanine|an L-cysteine desulfurase-L-cysteine|1-deoxy-D-xylulose 5-phosphate|H+|2-(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylideneethyl phosphate|L-tyrosine|4-methylphenol|pyruvate|CO2|5-deoxyadenosine
|
61
|
|
thiazole biosynthesis II (aerobic bacteria)
|
PWY-6891
|
cysteine desulfurase|[sulfur-carrier protein ThiS] adenylyltransferase|thiazole tautomerase|thiazole synthase|1-deoxyxylulose-5-phosphate synthase|thiazole tautomerase tenI|glycine oxidase
|
L-cysteine|H2O|2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate|2-iminoacetate|glycine|an L-cysteine desulfurase L-cysteine persulfide|diphosphate|hydrogen peroxide|an L-cysteine desulfurase-L-cysteine|L-alanine|1-deoxy-D-xylulose 5-phosphate|D-glyceraldehyde 3-phosphate|H+|2-(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylideneethyl phosphate|pyruvate|CO2|oxygen
|
61
|
|
superpathway of aerobic toluene degradation
|
PWY-5183
|
4-hydroxy-2-oxovalerate aldolase|β-ketoadipate enol-lactone hydrolase [PcaD]3|2-oxopent-4-enoate hydratase|4-hydroxybenzoate hydroxylase|benzoate 1,2-dioxygenase|toluene ortho-monooxygenase|4-oxalocrotonate decarboxylase, subunit of 4-oxalocrotonate/2-oxopent-4-enoate hydratase complex|toluene ortho-monooxygenase [(TomA3)2(TomA1)2(TomA4)2][TomA5][TomA2]|β-ketoadipate:succinyl CoA transferase [PcaI]2[PcaJ]2|4-hydroxybenzyl alcohol dehydrogenase [multifunctional]|benzyl alcohol dehydrogenase [XylB]2|toluene 1,2-dioxygenase|4-carboxymuconolactone decarboxylase [PcaC]6|toluene 3-monooxygenase|2-hydroxymuconic semialdehyde hydrolase|2-oxopent-4-enoate hydratase, subunit of 4-oxalocrotonate/2-oxopent-4-enoate hydratase complex|toluene 1,2-dioxygenase [(TodC1)2(TodC2)2][TodA][TodB]|xylene monooxygenase|2-hydroxymuconate semialdehyde hydrolase|3-methylcatechol 2,3-dioxygenase|toluene-4-monooxygenase|acylating aldehyde dehydrogenase|acetaldehyde dehydrogenase|2-hydroxymuconate tautomerase|benzyl alcohol dehydrogenase|1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase [multifunctional]|toluene 3-monooxygenase [(TbuA1)2(TbuA2)2(TbuU)2][TbuC][TbuV][TbuB]|2-hydroxymuconic semialdehyde hydrolase xylF|cis-toluene dihydrodiol dehydrogenase todD|2-hydroxy-6-oxohepta-2,4-dienoate hydrolase|catechol 2,3-dioxygenase|2-hydroxymuconate semialdehyde dehydrogenase|cis-toluene dihydrodiol dehydrogenase|benzaldehyde dehydrogenase
|
3-oxoadipyl-CoA|2-carboxy-5-oxo-2,5-dihydrofuran-2-acetate|NADPH|3-methylcatechol|3-carboxy-cis,cis-muconate|benzoate|4-hydroxybenzaldehyde|protocatechuate|3-oxoadipate|4-hydroxy-2-oxopentanoate|4-methylphenol|H2O|benzaldehyde|NAD+|acetyl-CoA|NADP+|acetaldehyde|3,5-cyclohexadiene-1,2-diol-1-carboxylate|(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate|4-hydroxybenzoate|formate|pyruvate|CO2|benzyl alcohol|acetate|(2Z,4E)-2-hydroxyhexa-2,4-dienedioate|3-oxoadipate enol lactone|4-hydroxybenzyl alcohol|(1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol|succinate|(3E)-2-oxohex-3-enedioate|oxygen|coenzyme A|cis,cis-2-hydroxy-6-oxohepta-2,4-dienoate|2-oxopent-4-enoate|H+|succinyl-CoA|toluene|4-methylcatechol|catechol|2-methylphenol|NADH
|
61
|
|
phenylacetate degradation I (aerobic)
|
PWY0-321
|
oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase paaZ|2,3-dehydroadipyl-CoA hydratase paaF|β-ketoadipyl-CoA thiolase|1,2-epoxyphenylacetyl-CoA isomerase paaG|3-hydroxyadipyl-CoA dehydrogenase (NAD+) paaH|ring 1,2-phenylacetyl-CoA epoxidase|1,2-epoxyphenylacetyl-CoA isomerase|3-hydroxyadipyl-CoA dehydrogenase (NAD+)|oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase|2,3-dehydroadipyl-CoA hydratase|phenylacetate-CoA ligase (aerobic)
|
3-oxoadipyl-CoA|trans-2,3-dehydroadipyl-coA|H2O|NAD+|phenylacetate|acetyl-CoA|diphosphate|2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA|NADP+|3-oxo-5,6-didehydrosuberyl-CoA semialdehyde|(3S)-hydroxyadipyl-CoA|2-oxepin-2(3H)-ylideneacetyl-CoA|H+|succinyl-CoA|NADPH|3-oxo-5,6-didehydrosuberyl-CoA|phenylacetyl-CoA|NADH|oxygen|coenzyme A
|
61
|
|
thiamine salvage II
|
PWY-6897
|
thiamine phosphate synthase|hydroxymethylpyrimidine kinase / phosphohydroxymethylpyrimidine kinase|4-amino-2-methyl-5-phosphomethylpyrimidine kinase|hydroxyethylthiazole kinase|pyridoxal kinase I / hydroxymethylpyrimidine kinase|thiamine monophosphate kinase
|
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine|5-(2-hydroxyethyl)-4-methylthiazole|4-methyl-5-(2-phosphooxyethyl)thiazole|diphosphate|4-amino-2-methyl-5-(diphosphomethyl)pyrimidine|thiamine phosphate|H+|thiamine diphosphate|4-amino-2-methyl-5-pyrimidinemethanol
|
61
|
|
D-galactose degradation I (Leloir pathway)
|
PWY-6317
|
UDP-galactose 4-epimerase|UDP-glucose 4-epimerase|galactose-1-epimerase|galactose-1-phosphate uridylyltransferase|galactose 1-phosphate uridyl transferase|UDP-glucose-4-epimerase|aldose-1-epimerase|phosphoglucomutase|galactokinase
|
α-D-glucopyranose 1-phosphate|UDP-α-D-glucose|α-D-galactose|β-D-galactose|α-D-galactose 1-phosphate|H+|D-glucopyranose 6-phosphate|UDP-α-D-galactose
|
60
|
|
2-methylbutanoate biosynthesis
|
PWY-5109
|
2-methyl branched-chain acyl-CoA dehydrogenase|2-methylacetoacetyl-coenzyme A reductase
|
2-methylacetoacetyl-CoA|acetate|NAD+|2-methylbutanoate|acetyl-CoA|(E)-2-methylcrotonoyl-CoA|H2O|(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA|H+|propanoyl-CoA|2-methylbutanoyl-CoA|propanoate|NADH|coenzyme A
|
60
|