|
L-proline biosynthesis II (from arginine)
|
PWY-4981
|
arginine deiminase|pyrroline-5-carboxylate reductase|citrullinase|ornithine δ-transaminase
|
carbamoyl phosphate|H2O|(S)-1-pyrroline-5-carboxylate|ammonium|L-ornithine|L-proline|L-glutamate-5-semialdehyde|L-arginine|L-glutamate|L-citrulline|H+|phosphate|2-oxoglutarate|CO2
|
65
|
|
superpathway of menaquinol-7 biosynthesis
|
PWY-5840
|
o-succinylbenzoate synthase|2-succinylbenzoate--CoA ligase|heptaprenyl diphosphate synthase [HepS][HepT]|1,4-dihydroxy-2-naphthoate heptaprenyltransferase|isochorismate synthase|heptaprenyl diphosphate synthase|2-oxoglutarate decarboxylase [multifunctional]|1,4-dihydroxy-2-naphthoate heptaprenyltransferase menA|naphthoyl-CoA synthase|S-adenosylmethionine:2-demethylmenaquinol methyltransferase
|
S-adenosyl-L-methionine|2-carboxy-1,4-naphthoquinol|demethylmenaquinol-7|H2O|4-(2-carboxyphenyl)-4-oxobutyryl-CoA|isochorismate|1,4-dihydroxy-2-naphthoyl-CoA|isopentenyl diphosphate|pyruvate|S-adenosyl-L-homocysteine|H+|all-trans-heptaprenyl diphosphate|coenzyme A|chorismate|diphosphate|CO2|(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate|menaquinol-7|2-succinylbenzoate|2-oxoglutarate|2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate|(2E,6E)-farnesyl diphosphate
|
64
|
|
reductive TCA cycle II
|
PWY-5392
|
citryl-coA lyase [Ccl]3|citryl-CoA synthetase|2-oxoglutarate carboxylase [CfiA]8[CfiB]8|oxalosuccinate reductase|2-oxoglutarate carboxylase|oxalosuccinate reductase [Icd]2|2-oxoglutarate synthase|pyruvate:ferredoxin oxidoreductase|citryl-coA lyase|citryl-CoA synthetase [CcsB]3[CcsA]3
|
fumarate|H2O|NAD+|acetyl-CoA|oxalosuccinate|succinate|(S)-malate|citrate|CO2|oxaloacetate|D-threo-isocitrate|H+|succinyl-CoA|phosphate|2-oxoglutarate|cis-aconitate|pyruvate|NADH|(3S)-citryl-CoA|coenzyme A
|
64
|
|
superpathway of phenylethylamine degradation
|
PWY-6071
|
oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase paaZ|2,3-dehydroadipyl-CoA hydratase paaF|β-ketoadipyl-CoA thiolase|1,2-epoxyphenylacetyl-CoA isomerase paaG|3-hydroxyadipyl-CoA dehydrogenase (NAD+) paaH|copper-containing amine oxidase|ring 1,2-phenylacetyl-CoA epoxidase|3-hydroxyadipyl-CoA dehydrogenase (NAD+)|oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase|phenylacetaldehyde dehydrogenase
|
3-oxoadipyl-CoA|2-phenylethylamine|NADPH|3-oxo-5,6-didehydrosuberyl-CoA semialdehyde|2-oxepin-2(3H)-ylideneacetyl-CoA|ammonium|(3S)-hydroxyadipyl-CoA|H2O|NAD+|acetyl-CoA|2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA|NADP+|trans-2,3-dehydroadipyl-coA|phenylacetate|phenylacetaldehyde|hydrogen peroxide|3-oxo-5,6-didehydrosuberyl-CoA|oxygen|coenzyme A|phenylacetyl-CoA|diphosphate|H+|succinyl-CoA|NADH
|
64
|
|
tetrapyrrole biosynthesis I (from glutamate)
|
PWY-5188
|
glutamyl-tRNA synthetase|uroporphyrinogen III synthase|glutamyl-tRNA reductase|glutamate-1-semialdehyde aminotransferase|uroporphyrinogen III cosynthetase|glutamate-1-semialdehyde 2,1-aminomutase|porphobilinogen deaminase|hydroxymethylbilane synthase|porphobilinogen synthase
|
H2O|NADPH|porphobilinogen|(S)-4-amino-5-oxopentanoate|diphosphate|uroporphyrinogen-III|NADP+|L-glutamate|preuroporphyrinogen|H+|ammonium|5-aminolevulinate
|
63
|
|
NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)
|
PWY-7269
|
aldehyde dehydrogenase, mitochondrial|NADH:ubiquinone oxidoreductase 1 (external)|NAD(+)/NADH kinase|NADH:ubiquinone oxidoreductase (internal)|potassium-activated aldehyde dehydrogenase, mitochondrial|NADH:ubiquinone oxidoreductase 2 (external)
|
H2O|NAD+|NADP+|H+|NADPH|NADH|a carboxylate
|
63
|
|
L-glutamate and L-glutamine biosynthesis
|
PWY-5505
|
glutamine synthetase, type III|glutamate dehydrogenase|glutamate dehydrogenase 1 (NADP-dependent)|glutamine synthetase|glutamine synthetase, type IV|glutamate dehydrogenase 2|glutamate synthase (NADH)|glutamate synthase (ferredoxin-dependent)|glutamate dehydrogenase 1|glutamate synthase|glutamate dehydrogenase 2 (NADP-dependent)|glutamine synthetase, type II|glutamate synthase (NADH-dependent)
|
H2O|NAD+|phosphate|ammonium|L-glutamine|NADP+|L-glutamate|H+|NADPH|2-oxoglutarate|NADH
|
63
|
|
L-isoleucine biosynthesis IV
|
PWY-5104
|
dihydroxy-acid dehydratase|ketol-acid reductoisomerase|branched-chain-amino-acid aminotransferase|α-ketobutyrate synthase
|
H2O|L-isoleucine|2-oxoglutarate|diphosphate|(R)-2,3-dihydroxy-3-methylpentanoate|2-oxobutanoate|L-glutamate|(S)-3-methyl-2-oxopentanoate|H+|propanoyl-CoA|propanoate|pyruvate|CO2|(S)-2-aceto-2-hydroxybutanoate|coenzyme A
|
62
|
|
NAD biosynthesis I (from aspartate)
|
PYRIDNUCSYN-PWY
|
quinolinate phosphoribosyltransferase (decarboxylating)|quinolinate phosphoribosyltransferase|NAD synthetase, NH3-dependent|quinolinate synthase|L-aspartate oxidase|nicotinate-mononucleotide adenylyltransferase|NAD synthetase, NH3-dependent [NadE]2|NAD synthetase (glutamine dependent)|nicotinate mononucleotide adenylyltransferase
|
H2O|NAD+|ammonium|L-glutamine|hydrogen peroxide|diphosphate|L-aspartate|2-iminosuccinate|quinolinate|L-glutamate|nicotinate adenine dinucleotide|H+|phosphate|5-phospho-α-D-ribose 1-diphosphate|glycerone phosphate|CO2|oxygen|β-nicotinate D-ribonucleotide
|
62
|
|
NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)
|
PWY-7268
|
NAD(+)/NADH kinase|NADP-dependent isocitrate dehydrogenase|magnesium-activated aldehyde dehydrogenase, cytosolic|glucose-6-phosphate dehydrogenase
|
6-phospho D-glucono-1,5-lactone|acetate|NADPH|D-glucopyranose 6-phosphate|NADP+|H2O|CO2|D-threo-isocitrate|H+|NAD+|acetaldehyde|2-oxoglutarate|NADH
|
62
|