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superpathway of acetyl-CoA biosynthesis
|
PWY-5173
|
pyruvate dehydrogenase complex|ATP-citrate lyase
|
NAD+|acetyl-CoA|a pyruvate dehydrogenase E2 protein N6-S-acetyldihydrolipoyl-L-lysine|citrate|CO2|oxaloacetate|a pyruvate dehydrogenase E2 protein N6-lipoyl-L-lysine|H+|phosphate|a pyruvate dehydrogenase E2 protein N6-dihydrolipoyl-L-lysine|pyruvate|NADH|coenzyme A
|
68
|
|
superpathway of ergosterol biosynthesis II
|
PWY-7156
|
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase ispG|sterol C-5 desaturase ERG3|sterol C-5 desaturase
|
S-adenosyl-L-methionine|NADPH|dimethylallyl diphosphate|cycloartenol|geranyl diphosphate|(24R)-24-methylcycloarta-25-en-3-β-ol|ergosta-5,7-dienol|1-deoxy-D-xylulose 5-phosphate|2-C-methyl-D-erythritol-2,4-cyclodiphosphate|2-C-methyl-D-erythritol 4-phosphate|H2O|(3S)-2,3-epoxy-2,3-dihydrosqualene|ergosta-8,25(27)-dienol|NADP+|isopentenyl diphosphate|D-glyceraldehyde 3-phosphate|ergosterol|pyruvate|S-adenosyl-L-homocysteine|ergost-7-enol|ergosta-7,25(27)-dienol|2-phospho-4-(cytidine 5-diphospho)-2-C-methyl-D-erythritol|oxygen|(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate|4α, 14α-dimethyl ergosta-8,25(27)-dienol|diphosphate|squalene|CO2|H+|4-(cytidine 5-diphospho)-2-C-methyl-D-erythritol|(2E,6E)-farnesyl diphosphate
|
67
|
|
fatty acid β-oxidation (peroxisome, yeast)
|
PWY-7288
|
fatty-acyl coenzyme A oxidase|peroxisomal multifunctional enzyme type 2|3-ketoacyl-CoA thiolase / 3-oxoacyl CoA thiolase|medium-chain acyl-CoA synthetase
|
H2O|a trans-2-enoyl-CoA|NAD+|acetyl-CoA|diphosphate|hydrogen peroxide|H+|a 2,3,4-saturated fatty acid|NADH|oxygen|coenzyme A
|
67
|
|
L-tryptophan degradation III (eukaryotic)
|
TRYPTOPHAN-DEGRADATION-1
|
indoleamine 2,3-dioxygenase|3-hydroxyanthranilate 3,4-dioxygenase|kynureninase|mitochondrial enoyl-CoA hydratase|Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial|aminocarboxymuconate-semialdehyde decarboxylase|kynurenine 3-monooxygenase|arylformamidase|peroxisomal bifunctional enzyme|tryptophan 2,3-dioxygenase|3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit|probable 2-oxoglutarate dehydrogenase E1 component DHKTD1|glutaryl-CoA dehydrogenase [GcdH]4|cytosolic acetyl-CoA acetyltransferase|acetyl-CoA C-acetyltransferase|mitochondrial acetyl-CoA acetyltransferase
|
NADPH|2-oxoadipate|(S)-3-hydroxybutanoyl-CoA|ammonium|crotonyl-CoA|glutaryl-CoA|H2O|N-formylkynurenine|3-hydroxyanthranilate|acetyl-CoA|NADP+|L-alanine|L-tryptophan|acetoacetyl-CoA|(2Z,4E)-2-amino-6-oxohexa-2,4-dienoate|formate|CO2|H+|(2Z,4E)-2-aminomuconate|NAD+|oxygen|coenzyme A|(E)-glutaconyl-CoA|3-hydroxy-L-kynurenine|aminocarboxymuconate semialdehyde|L-kynurenine|(3E)-2-oxohex-3-enedioate|NADH
|
67
|
|
photorespiration
|
PWY-181
|
glycine decarboxylase|D-glycerate 3-kinase GLYK|serine:glyoxylate aminotransferase|glyoxylate aminotransferase|peroxisomal (S)-2-hydroxy-acid oxidase GLO1|alanine transaminase|phosphoglycolate phosphatase|D-glycerate 3-kinase|serine hydroxymethyltransferase|hydroxypyruvate reductase|ribulose bisphosphate carboxylase/oxygenase|peroxisomal (S)-2-hydroxy-acid oxidase
|
glycine|ammonium|a 5,10-methylene-tetrahydrofolate|2-phosphoglycolate|hydroxypyruvate|H2O|NAD+|glyoxylate|L-glutamate|glycolate|phosphate|CO2|L-serine|a tetrahydrofolate|hydrogen peroxide|D-glycerate|oxygen|3-phospho-D-glycerate|D-ribulose-1,5-bisphosphate|H+|2-oxoglutarate|NADH
|
67
|
|
superpathway of sulfolactate degradation
|
PWY-6641
|
sulfolactate dehydrogenase slcD|sulfolactate dehydrogenase|L-cysteate aminotransferase|sulfopyruvate decarboxylase|L-cysteate sulfo-lyase|phosphate acetyltransferase|sulfoacetaldehyde acetyltransferase
|
H2O|acetyl-CoA|L-cysteate|ammonium|2-oxoglutarate|3-sulfopyruvate|3-sulfolactate|acetyl phosphate|sulfoacetaldehyde|sulfite|L-glutamate|H+|phosphate|pyruvate|CO2|coenzyme A
|
67
|
|
superpathway of pyrimidine nucleobases salvage
|
PWY-7208
|
CTP synthase|UMP kinase|uridylate kinase|nucleoside diphosphate kinase|UMP/CMP kinase|nucleoside-diphosphate kinase 1|uracil phosphoribosyltransferase
|
H2O|L-glutamine|L-glutamate|H+|uracil|phosphate|5-phospho-α-D-ribose 1-diphosphate|diphosphate
|
67
|
|
teichoic acid (poly-glycerol) biosynthesis
|
TEICHOICACID-PWY
|
UDP-N-acetylmannosamine transferase tagA|UDP-N-acetylglucosamine 2-epimerase|poly(glycerol-phosphate) α-glucosyltransferase|glycerol-3-phosphate cytidylyltransferase [TagD]2|CDP-glycerol : glycerophosphate glycerophosphotransferase|CDP-glycerol : poly(glycerophosphate) glycerophosphotransferase tagF|glycerol-3-phosphate cytidylyltransferase|CDP-glycerol : glycerophosphate glycerophosphotransferase tagB|UDP-N-acetylmannosamine transferase|UDP-N-acetylglucosamine : undecaprenyl-P N-acetylglucosaminyl 1-P transferase|CDP-glycerol : poly(glycerophosphate) glycerophosphotransferase|poly(glycerol-phosphate) α-glucosyltransferase tagE
|
a peptidoglycan-P-GlcNAc-ManNAc-P-Gro-(P-Gro)m(Glc)n|a prenyl-P-P-GlcNAc-ManNAc-P-Gro-(P-Gro)m-(Glc)n|N-acetyl-β-D-mannosaminyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol|di-trans,octa-cis-undecaprenyl phosphate|diphosphate|N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol|UDP-N-acetyl-α-D-glucosamine|prenyl-P-P-GlcNAc-ManNAc-P-Gro|CDP-glycerol|H+|sn-glycerol 3-phosphate|a prenyl-P-P-GlcNAc-ManNAc-P-Gro-(P-Gro)n|UDP-α-D-glucose
|
66
|
|
L-glutamine biosynthesis III
|
PWY-6549
|
NAD+-dependent isocitrate dehydrogenase|phosphoenolpyruvate carboxylase|glutamine synthetase|glutamate synthase (ferredoxin-dependent)|NADP+-dependent isocitrate dehydrogenase|citrate synthase (mitochondrial)|aconitase
|
NADPH|L-glutamine|NADP+|ammonium|H2O|NAD+|acetyl-CoA|hydrogen carbonate|oxaloacetate|L-glutamate|D-threo-isocitrate|phosphate|pyruvate|CO2|citrate|phosphoenolpyruvate|coenzyme A|diphosphate|H+|cis-aconitate|2-oxoglutarate|NADH
|
66
|
|
formaldehyde oxidation I
|
RUMP-PWY
|
hexulose-6-phosphate synthase|NAD+-dependent 6-phosphogluconate dehydrogenase|glucose-6-phosphate dehydrogenase|6-phospho-3-hexuloisomerase
|
D-ribulose 5-phosphate|H2O|NAD+|6-phospho D-glucono-1,5-lactone|hexulose 6-phosphate|D-gluconate 6-phosphate|formaldehyde|NADP+|CO2|β-D-fructofuranose 6-phosphate|H+|NADPH|D-glucopyranose 6-phosphate|NADH
|
65
|