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lipoate biosynthesis and incorporation III (Bacillus)
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PWY-6987
|
GcvH:[lipoyl domain] amidotransferase lipL|octanoyl transferase|GcvH:[lipoyl domain] amidotransferase|lipoyl synthase (lipoic acid synthetase)
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S-adenosyl-L-methionine|L-methionine|a glycine-cleavage complex H protein N6-octanoyl-L-lysine|glycine cleavage system lipoyl-carrier protein-L-lysine|H+|5-deoxyadenosine
|
0
|
|
lipoate salvage I
|
PWY0-522
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lipoate-protein ligase|lipoate-protein ligase A
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diphosphate|(R)-lipoate|lipoyl-adenylate|H+
|
0
|
|
lipoate salvage II
|
PWY-6984
|
lipoyl amidotransferase lipL|lipoyl amidotransferase|lipoamidase|lipoate—protein ligase
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H2O|a glycine-cleavage complex H protein N6-lipoyl-L-lysine|lipoyl-adenylate|diphosphate|(R)-lipoate|glycine cleavage system lipoyl-carrier protein-L-lysine|H+
|
0
|
|
lipoxin biosynthesis
|
PWY66-392
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arachidonate 12-lipoxygenase|arachidonate 15-lipoxygenase|arachidonate 12-lipoxygenase ALOX12|arachidonate 5-lipoxygenase ALOX5|arachidonate 5-lipoxygenase
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H2O|leukotriene A4|lipoxin B4|15S-hydroxypentaenoate|lipoxin A4|oxygen|arachidonate
|
0
|
|
lolitrem B biosynthesis
|
PWY-7572
|
multifunctional diprenyltransferase|multifunctional cytochrome P450 monooxygenase|multifunctional diprenyltransferase LtmE|multifunctional aromatic O-prenyltransferase LtmF|multifunctional cytochrome P450 monooxygenase LtmP|multifunctional cytochrome P450 monooxygenase LtmK|multifunctional aromatic O-prenyltransferase|multifunctional cytochrome P450 monooxygenase LtmQ|multifunctional cytochrome P450 monooxygenase LtmJ
|
NADPH|paspaline|terpendole J|terpendole G|terpendole B|20,21-diprenylterpendole C|H2O|terpendole E|lolitrem B|dimethylallyl diphosphate|NADP+|lolitriol|formate|20,21-diprenylterpendole I|terpendole I|terpendole C|oxygen|diphosphate|terpendole F|lolitrem E|H+|20,21-diprenylterpendole J
|
0
|
|
long chain fatty acid ester synthesis (engineered)
|
PWY-6873
|
wax ester synthase/acyl-CoA diacylglycerol acyltransferase bifunctional enzyme atfA|alcohol dehydrogenase II|pyruvate decarboxylase|wax ester synthase/acyl-CoA diacylglycerol acyltransferase bifunctional enzyme
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a fatty acid-ethyl ester|diphosphate|acetaldehyde|H+|pyruvate|CO2|ethanol|coenzyme A
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0
|
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long-chain fatty acid activation
|
PWY-5143
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long-chain acyl-CoA synthetase 9|long chain acyl-CoA synthetase 5|long-chain acyl-CoA synthetase 4
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diphosphate|coenzyme A
|
0
|
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lotaustralin biosynthesis
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PWY-5990
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CYP71E7 CYP71E7|isoleucine N-monooxygenase (oxime forming)|valine N-monooxygenase (oxime forming)|CYP71E7|UDP-glucose:acetone cyanohydrin β-glucosyltransferase
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2-hydroxy-2-methylbutyronitrile|(Z)-2-methylbutanal oxime|H2O|L-isoleucine|NADPH|UDP-α-D-glucose|NADP+|2-methylbutyronitrile|N-hydroxy-L-isoleucine|N,N-dihydroxy-L-isoleucine|lotaustralin|H+|CO2|oxygen|(E)-2-methylbutanal oxime
|
0
|
|
lotaustralin degradation
|
PWY-6002
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β-glucosidase|lotaustralin beta-glucosidase|aliphatic (R)-hydroxynitrile lyase
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hydrogen cyanide|H2O|(2R)-2-hydroxy-2-methylbutanenitrile|lotaustralin|butan-2-one
|
0
|
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lovastatin biosynthesis
|
PWY-7535
|
2-methylbutanoate polyketide synthase|monacolin J acid methylbutanoate transferase lovD|monacolin J acid methylbutanoate transferase|2-methylbutanoate polyketide synthase lovF|lovastatin nonaketide synthase complex [LovB][LovC]|dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase|dihydromonacolin L hydroxylase|lovastatin nonaketide synthase complex|dihydromonacolin L hydroxylase lovA|dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase lovG
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S-adenosyl-L-methionine|3α-hydroxy-3,5-dihydromonacolin L acid|H2O|NADPH|acetyl-CoA|lovastatin acid|NADP+|monacolin L acid|dihydromonacolin L acid|monacolin J acid|H+|S-adenosyl-L-homocysteine|malonyl-CoA|CO2|oxygen|coenzyme A
|
0
|