fatty acid elongation -- saturated
|
FASYN-ELONG-PWY
|
3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic|enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase|KASII|KASI|β-hydroxyacyl-ACP dehydratase/isomerase|3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic|enoyl-[acyl-carrier-protein] reductase|3-hydroxyacyl-[acp] dehydrase|3-oxoacyl-[acyl-carrier-protein] reductase|enoyl-[acyl-carrier-protein] reductase (NADPH)
|
H2O|NAD+|NADP+|CO2|H+|NADPH|NADH
|
539
|
(5Z)-dodec-5-enoate biosynthesis
|
PWY0-862
|
enoyl-[acyl-carrier-protein] reductase [FabI]4|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase [FabZ]6|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase|3-oxoacyl-[acyl-carrier-protein] reductase|3-oxoacyl-[acyl-carrier-protein] reductase [FabG]4|KASI|β-hydroxyacyl-ACP dehydratase/isomerase|3-hydroxyacyl-[acyl-carrier-protein] dehydratase/isomerase|(5Z)-3-oxo-dodec-5-enoyl-[acp] synthase|enoyl-[acyl-carrier-protein] reductase|trans-2-decenoyl-[acyl-carrier-protein] isomerase
|
H2O|NAD+|NADP+|CO2|H+|NADPH|NADH
|
528
|
oleate biosynthesis IV (anaerobic)
|
PWY-7664
|
3-oxoacyl-[acyl-carrier-protein] reductase|3-hydroxyacyl-[acyl-carrier-protein] dehydratase/isomerase [FabQ]6|3-oxoacyl-[acyl-carrier-protein] reductase fabG|enoyl-[acyl-carrier-protein] reductase fabK|3-oxoacyl-[acyl-carrier-protein] synthase|3-hydroxyacyl-[acyl-carrier-protein] dehydratase/isomerase|3-oxoacyl-[acyl-carrier-protein] synthase fabF|enoyl-[acyl-carrier-protein] reductase
|
H2O|NAD+|NADP+|CO2|H+|NADPH|NADH
|
528
|
Methanobacterium thermoautotrophicum biosynthetic metabolism
|
PWY-6146
|
NADP-dependent formate dehydrogenase [FdhA]2[FdhB]2|ADP-dependent phosphofructokinase [PfkA]4|glyceraldehyde-3-phosphate ferredoxin oxidoreductase gor|(NAD(P)-dependent glycerol-1-phosphate dehydrogenase|phosphopyruvate hydratase|formylmethanofuran dehydrogenase, tungsten enzyme|H2-forming methylene-H4MPT dehydrogenase|F420-dependent methylene-H4MPT reductase|triosephosphate isomerase|phosphoglycerol geranylgeranyltransferase|F420-dependent methylene-H4MPT reductase [Mer]4|phosphoglycerol geranylgeranyltransferase [MTH_552]5|digeranylgeranylglyceryl phosphate synthase MTH_1098|formylmethanofuran dehydrogenase, molybdenum enzyme|methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase [AcsE]2|phosphoenolpyruvate carboxylase|pyruvate carboxylase|formylmethanofuran:H4MPT formyltransferase|H2-forming methylene-H4MPT dehydrogenase [Hmd]4|methenyl-H4MPT cyclohydrolase|pyruvate synthase|digeranylgeranylglyceryl phosphate synthase|archaetidylserine synthase|2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1|archaetidylserine synthase MTH1027|2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2|2,3-di-O-geranylgeranyl-sn-glycerol 1-phosphate reductase Ta0516|archaetidylserine decarboxylase|carbonic anhydrase|ferredoxin-dependent methylenetetrahydrofolate reductase [methylenetetrahydrofolate reductase (ferredoxin) α subunit]4[methylenetetrahydrofolate reductase (ferredoxin) β subunit]4|(NAD(P)-dependent glycerol-1-phosphate dehydrogenase [EgsA]8|CDP-archaeol synthase
|
fumarate|NADPH|tetrahydromethanopterin|a formyl-methanofuran|geranyl diphosphate|saturated archaetidylethanolamine|hydrogen carbonate|5-formyl-tetrahydromethanopterin|geranylgeranyl diphosphate|sn-glycerol 1-phosphate|glycerone phosphate|a reduced coenzyme F420|a 5,10-methenyltetrahydrofolate|H2O|a 5,10-methylene-tetrahydrofolate|NAD+|dimethylallyl diphosphate|acetyl-CoA|β-D-fructofuranose 6-phosphate|N5-methyltetrahydromethanopterin|NADP+|L-alanine|D-glyceraldehyde 3-phosphate|isopentenyl diphosphate|2,3-bis-O-phytanyl-sn-glycerol 1-phosphate|oxaloacetate|L-glutamate|(R)-mevalonate diphosphate|acetoacetyl-CoA|phosphate|formate|pyruvate|CO2|3-(O-geranylgeranyl)-sn-glycerol 1-phosphate|L-serine|a tetrahydrofolate|unsaturated CDP-archaeol|unsaturated archaetidylethanolamine|phosphoenolpyruvate|5,10-methylene-tetrahydromethanopterin|(S)-malate|(R)-mevalonate 5-phosphate|an N5-methyl-tetrahydrofolate|(R)-mevalonate|unsaturated archaetidylserine|succinate|(S)-3-hydroxy-3-methylglutaryl-CoA|coenzyme A|carbon monoxide|5,10-methenyltetrahydromethanopterin|3-phospho-D-glycerate|D-glucopyranose 6-phosphate|diphosphate|2-phospho-D-glycerate|H2|fructose 1,6-bisphosphate|saturated CDP-archaeol|L-aspartate|an N10-formyl-tetrahydrofolate|H+|succinyl-CoA|2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate|2-oxoglutarate|NADH|(2E,6E)-farnesyl diphosphate|saturated archaetidylserine
|
459
|
stearate biosynthesis II (bacteria and plants)
|
PWY-5989
|
long-chain acyl-CoA synthetase 9|3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic|enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic|3-ketoacyl-[acp] synthase 2, chloroplastic|3-hydroxyacyl-[acp] dehydrase
|
H2O|NAD+|diphosphate|stearoyl-CoA|NADP+|CO2|stearate|H+|NADPH|malonyl-CoA|NADH|coenzyme A
|
409
|
superpathway of purine nucleotides de novo biosynthesis II
|
DENOVOPURINE2-PWY
|
phosphoribosylformylglycinamide synthetase|N5-carboxyaminoimidazole ribonucleotide mutase [PurE]8|N5-carboxyaminoimidazole ribonucleotide synthetase [PurK]2|GMP synthetase|ribonucleoside-triphosphate reductase [NrdD]2|N5-carboxyaminoimidazole ribonucleotide synthetase|nucleoside diphosphate kinase|ribonucleoside diphosphate reductase 1|guanylate kinase|amidophosphoribosyl transferase|phosphoribosylformylglycinamide cyclo-ligase|IMP dehydrogenase|ribonucleoside-triphosphate reductase, subunit of anaerobic nucleoside-triphosphate reductase activating system|adenylosuccinate lyase|N5-carboxyaminoimidazole ribonucleotide mutase|adenylate kinase|ribonucleoside-diphosphate reductase 2|phosphoribosylaminoimidazole-succinocarboxamide synthase|AICAR transformylase / IMP cyclohydrolase|phosphoribosylamine-glycine ligase|adenylosuccinate synthetase
|
fumarate|H2O|N5-carboxyaminoimidazole ribonucleotide|NAD+|glycine|a tetrahydrofolate|an N10-formyl-tetrahydrofolate|L-glutamine|hydrogen carbonate|diphosphate|L-aspartate|adenylo-succinate|5-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole|L-glutamate|H+|5-phospho-β-D-ribosylamine|phosphate|5-phospho-α-D-ribose 1-diphosphate|formate|NADH
|
395
|
superpathway of purine nucleotides de novo biosynthesis I
|
PWY-841
|
multifunctional protein ADE2|adenylosuccinate lyase|adenylosuccinate lyase [multifunctional]|bifunctional purine biosynthesis protein ADE17|nucleoside-diphosphate kinase 1|phosphoribosylpyrophosphate amidotransferase|adenylate kinase 1|bifunctional purine biosynthetic protein ADE5,7|adenylosuccinate synthase|nucleoside diphosphate kinase|phosphoribosylaminoimidazole carboxylase|GMP synthase|amidophosphoribosyltransferase|guanylate kinase|phosphoribosylformylglycinamidine synthase|ribonucleoside-diphosphate reductase|phosphoribosylamidoimidazole-succinocarboxamide synthetase|adenylate kinase|bifunctional purine biosynthesis protein ADE16|bifunctional purine biosynthesis protein PURH|phosphoribosylglycinamide formyltransferase|phosphoribosylformylglycinamidine synthetase|adenylate kinase isoenzyme 5|adenylosuccinate synthetase
|
fumarate|H2O|NAD+|glycine|a tetrahydrofolate|an N10-formyl-tetrahydrofolate|L-glutamine|diphosphate|CO2|adenylo-succinate|5-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole|L-glutamate|H+|5-phospho-β-D-ribosylamine|phosphate|5-phospho-α-D-ribose 1-diphosphate|L-aspartate|NADH
|
387
|
aspartate superpathway
|
PWY0-781
|
3-phosphoserine aminotransferase [multifunctional]|homoserine O-succinyltransferase [MetA]2|diaminopimelate decarboxylase|cobalamin-independent homocysteine transmethylase|tetrahydrodipicolinate succinylase|tetrahydrodipicolinate succinylase [DapD]2|O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase|aspartate aminotransferase, PLP-dependent|N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase|L-aspartate oxidase|NAD synthetase, NH3-dependent [NadE]2|cobalamin-dependent methionine synthase|4-hydroxy-tetrahydrodipicolinate reductase|bifunctional β-cystathionase, PLP-dependent and regulator of maltose regulon|quinolinate phosphoribosyltransferase|methionine adenosyltransferase|nicotinate-mononucleotide adenylyltransferase|diaminopimelate epimerase|4-hydroxy-tetrahydrodipicolinate synthase|aspartate kinase III|homoserine O-succinyltransferase|aspartate kinase / homoserine dehydrogenase|O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase [MetB]4|quinolinate synthase|homoserine kinase|aspartate semialdehyde dehydrogenase|NAD synthetase, NH3-dependent|N-succinyl-L-diaminopimelate desuccinylase|cystathionine-β-lyase / L-cysteine desulfhydrase|threonine synthase
|
S-adenosyl-L-methionine|nicotinate adenine dinucleotide|NADPH|L-glutamine|2-iminosuccinate|L,L-diaminopimelate|N-succinyl-2-amino-6-ketopimelate|ammonium|glycerone phosphate|L-cysteine|H2O|NAD+|meso-diaminopimelate|L-homocysteine|NADP+|O-succinyl-L-homoserine|oxaloacetate|L-glutamate|L-homoserine|phosphate|5-phospho-α-D-ribose 1-diphosphate|β-nicotinate D-ribonucleotide|pyruvate|CO2|L-cystathionine|2-aminoprop-2-enoate|N5-methyl--tetrahydropteroyl tri-L-glutamate|L-methionine|a tetrahydrofolate|L-aspartyl-4-phosphate|tetrahydropteroyl tri-L-glutamate|L-lysine|L-threonine|hydrogen peroxide|an N5-methyl-tetrahydrofolate|succinate|oxygen|coenzyme A|N-succinyl-L,L-2,6-diaminopimelate|diphosphate|L-aspartate-semialdehyde|L-aspartate|quinolinate|(S)-2,3,4,5-tetrahydrodipicolinate|O-phospho-L-homoserine|H+|succinyl-CoA|2-oxoglutarate|(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
|
366
|
stearate biosynthesis III (fungi)
|
PWY3O-355
|
fatty acid synthase, β subunit|fatty acid synthase, β subunit FAS1|fatty acid synthase, α subunit
|
H2O|NADPH|stearoyl-CoA|NADP+|stearate|H+|CO2|coenzyme A
|
363
|
superpathway of N-acetylneuraminate degradation
|
P441-PWY
|
glucosamine-6-phosphate deaminase|phosphoglycerate kinase|pyruvate kinase|glyceraldehyde 3-phosphate dehydrogenase|N-acetylglucosamine-6-phosphate deacetylase|pyruvate kinase I|fructose bisphosphate aldolase class I|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase|6-phosphofructokinase I|fructose bisphosphate aldolase class II|pyridoxal phosphatase / fructose 1,6-bisphosphatase|ethanol dehydrogenase / alcohol dehydrogenase|triosephosphate isomerase|N-acetylmannosamine-6-phosphate 2-epimerase|N-acetylneuraminate lyase|fructose 1,6-bisphosphatase II|fructose-1,6-bisphosphatase I|2-ketobutyrate formate-lyase / pyruvate formate-lyase 4|enolase, subunit of degradosome|phosphoenolpyruvate synthetase|phosphate acetyltransferase|N-acetyl-β-neuraminate lyase / N-acetylneuraminate lyase|N-acetylmannosamine-6-phosphate 2-epimerase [NanE]2|pyruvate formate-lyase / 2-ketobutyrate formate-lyase|phosphate acetyltransferase / phosphate propionyltransferase|aldehyde-alcohol dehydrogenase|6-phosphofructokinase II|N-acetylmannosamine kinase|acetaldehyde dehydrogenase 2|alkaline phosphatase|pyruvate kinase II|acetate kinase|fructose-1,6-bisphosphatase|2,3-bisphosphoglycerate-independent phosphoglycerate mutase
|
D-glucosamine 6-phosphate|N-acetyl-D-glucosamine 6-phosphate|acetate|ammonium|H2O|NAD+|acetyl-CoA|β-D-fructofuranose 6-phosphate|acetaldehyde|D-glyceraldehyde 3-phosphate|phosphate|N-acetyl-D-mannosamine|pyruvate|ethanol|acetyl phosphate|coenzyme A|phosphoenolpyruvate|1,3-bisphospho-D-glycerate|formate|3-phospho-D-glycerate|N-acetyl-D-mannosamine 6-phosphate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|glycerone phosphate|α-D-glucosamine 6-phosphate|H+|NADH
|
340
|