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superpathway of aromatic compound degradation via 2-oxopent-4-enoate
|
PWY-6954
|
4-hydroxy-2-oxovalerate aldolase|2-oxopent-4-enoate hydratase|salicylate 1-hydroxylase|benzoate 1,2-dioxygenase|naphthalene 1,2-dioxygenase complex|trans-o-hydroxybenzylidenepyruvate hydratase-aldolase nahE|4-oxalocrotonate decarboxylase, subunit of 4-oxalocrotonate/2-oxopent-4-enoate hydratase complex|1,2-dihydroxynaphthalene dioxygenase|protocatechuate 2,3-dioxygenase|2-hydroxymuconate semialdehyde dehydrogenase|NADP+-benzaldehyde dehydrogenase|1,2-dihydroxynaphthalene dioxygenase [NahC]|dehydroshikimate dehydratase|p-hydroxybenzoate hydroxylase|kynureninase|4-oxalocrotonate decarboxylase|2-hydroxychromene-2-carboxylate isomerase [NahD]2|quinate/shikimate dehydrogenase|cis-1,2-dihydro-1,2-dihydroxynaphthalene-1, 2-dehydrogenase|toluene 1,2-dioxygenase|acetaldehyde dehydrogenase|anthranilate dioxygenase|(S)-mandelate dehydrogenase|2-hydroxymuconic semialdehyde hydrolase|2-oxopent-4-enoate hydratase, subunit of 4-oxalocrotonate/2-oxopent-4-enoate hydratase complex|benzoylformate decarboxylase|mandelate racemase|mandelate racemase mdlA|toluene 1,2-dioxygenase [(TodC1)2(TodC2)2][TodA][TodB]|benzaldehyde dehydrogenase|tryptophan dioxygenase|salicylaldehyde dehydrogenase|4-hydroxy-2-ketovalerate aldolase|3-methylcatechol 2,3-dioxygenase|acylating aldehyde dehydrogenase|2-hydroxymuconate-6-semialdehyde dehydrogenase|catabolic 3-dehydroquinate dehydratase|2-hydroxymuconate tautomerase|protocatechuate 2,3-dioxygenase [PraA]4|1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase [multifunctional]|4-hydroxybenzaldehyde dehydrogenase|salicylate hydroxylase|2-hydroxymuconic semialdehyde hydrolase xylF|cis-toluene dihydrodiol dehydrogenase todD|2-hydroxy-6-oxohepta-2,4-dienoate hydrolase|benzaldehyde dehydrogenase [multifunctional]|catechol 2,3-dioxygenase|trans-o-hydroxybenzylidenepyruvate hydratase-aldolase|aldehyde dehydrogenase|2-hydroxychromene-2-carboxylate isomerase|5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase|cis-1,2-dihydro-1,2-dihydroxynaphthalene-1, 2-dehydrogenase [NahB]4|4-oxalocrotonate tautomerase|cis-toluene dihydrodiol dehydrogenase|(S)-mandelate dehydrogenase mdlB
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NADPH|trans-O-hydroxybenzylidenepyruvate|(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde|3-methylcatechol|N-formylkynurenine|benzoate|(S)-4-hydroxymandelate|(S)-mandelate|protocatechuate|4-hydroxybenzaldehyde|ammonium|2-hydroxychromene-2-carboxylate|naphthalene-1,2-diol|H2O|benzaldehyde|NAD+|acetyl-CoA|3,5-cyclohexadiene-1,2-diol-1-carboxylate|NADP+|L-alanine|acetaldehyde|3-dehydroshikimate|(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate|4-hydroxybenzoate|L-tryptophan|phenylglyoxylate|formate|pyruvate|CO2|acetate|(2Z,4E)-2-hydroxyhexa-2,4-dienedioate|cis naphthalene dihydrodiol|shikimate|L-kynurenine|(R)-mandelate|(R)-4-hydroxymandelate|(1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol|salicylate|L-quinate|oxygen|coenzyme A|naphthalene|anthranilate|2-oxopent-4-enoate|cis,cis-2-hydroxy-6-oxohepta-2,4-dienoate|4-hydroxy-2-oxopentanoate|2-(4-hydroxyphenyl)-2-oxoacetate|3-dehydroquinate|H+|toluene|(3E)-2-oxohex-3-enedioate|catechol|NADH|salicylaldehyde
|
85
|
|
jasmonic acid biosynthesis
|
PWY-735
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allene oxide cyclase|OPC6 acyl-CoA oxidase / OPC8 acyl-CoA oxidase / acyl-CoA oxidase|12-oxophytodienoate reductase|peroxisomal fatty acid β-oxidation multifunctional protein AIM1 AIM1|allene oxide synthase [AOS]|lipoxygenase|OPC4 acyl-CoA oxidase / OPC6 acyl-CoA oxidase / OPC8 acyl-CoA oxidase|peroxisomal fatty acid β-oxidation multifunctional protein AIM1|allene oxide synthase|allene oxide cyclase [AOC2]3|OPC4-3-ketoacyl-CoA thiolase [multifunctional]
|
3-oxo-2-(cis-2-pentenyl)-cyclopentane-1-octa-2-enoyl-CoA|NADPH|OPC6-CoA|(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate|α-linolenate|H2O|3-oxo-2-(cis-2-pentenyl)-cyclopentane-1-octanoate|OPC4-CoA|acetyl-CoA|3-oxo-2-(cis-2-pentenyl)-cyclopentane-1-octanoyl-CoA|NADP+|OPC6-3-ketoacyl-CoA|OPC8-3-ketoacyl-CoA|OPC4-trans-2-enoyl-CoA|hydrogen peroxide|NAD+|(+)-7-iso-jasmonate|oxygen|coenzyme A|OPC6-trans-2-enoyl-CoA|13(S)-HPOTE|OPC4-3-ketoacyl-CoA|OPC4-3-hydroxyacyl-CoA|diphosphate|jasmonoyl-CoA|(-)-jasmonate|OPC6-3-hydroxyacyl-CoA|H+|12-oxo-cis-10,15-phytodienoate|NADH
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84
|
|
superpathway of lipoxygenase
|
PWY-5433
|
linoleate 13S-lipoxygenase|9S-lipoxygenase 1|acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase|acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase AT3G03480|OPC4 acyl-CoA oxidase / OPC6 acyl-CoA oxidase / OPC8 acyl-CoA oxidase|peroxisomal fatty acid β-oxidation multifunctional protein AIM1|13S/9S lipoxygenase|allene oxide cyclase [AOC2]3|13-divinyl ether synthase|aldo-keto reductase family 4 member C9|12-oxophytodienoate reductase|allene oxide cyclase|allene oxide synthase|9S-lipoxygenase|OPC6 acyl-CoA oxidase / OPC8 acyl-CoA oxidase / acyl-CoA oxidase|peroxisomal fatty acid β-oxidation multifunctional protein AIM1 AIM1|9-divinyl ether synthase StDES|lipoxygenase|9/13-hydroperoxide lyase|9-divinyl ether synthase|OPC4-3-ketoacyl-CoA thiolase [multifunctional]|9-allene oxide synthase|allene oxide synthase [AOS]|aldehyde reductase (cytosolic)|hydroperoxide lyase|aldehyde reductase (chloroplastic)|aldehyde reductase
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3-oxo-2-(cis-2-pentenyl)-cyclopentane-1-octa-2-enoyl-CoA|(3Z)-hex-3-en-1-yl acetate|NADPH|OPC6-CoA|9,10-epoxy-10,12Z,15Z-octadecatrienoate|(9Z,11E,1E)-12-(1-hexenyloxy)-9,11-dodecadienoate|(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate|(13S)-HPODE|colnelenate|1-hexanal|α-linolenate|9,10-epoxy-10,12Z-octadecadienoate|H2O|3-oxo-2-(cis-2-pentenyl)-cyclopentane-1-octanoate|OPC4-CoA|(9S)-HPODE|acetyl-CoA|3-oxo-2-(cis-2-pentenyl)-cyclopentane-1-octanoyl-CoA|NADP+|(E)-2-hexenol|OPC4-3-ketoacyl-CoA|OPC6-3-ketoacyl-CoA|linoleate|(E)-2-hexenal|OPC4-trans-2-enoyl-CoA|OPC8-3-ketoacyl-CoA|(Z)-3-hexanal|(12Z)-9-hydroxy-10-oxo-octadec-12-enoate|(9Z)-12-oxo-dodec-9-enoate|traumatin|hydrogen peroxide|NAD+|colneleate|(+)-7-iso-jasmonate|oxygen|coenzyme A|OPC6-trans-2-enoyl-CoA|13(S)-HPOTE|9-oxo-nonanoate|(3Z)-3-nonenal|OPC4-3-hydroxyacyl-CoA|diphosphate|jasmonoyl-CoA|(-)-jasmonate|(3Z,6Z)-nonadienal|OPC6-3-hydroxyacyl-CoA|H+|(Z)-hex-3-en-ol|12-oxo-cis-10,15-phytodienoate|9(S)-HPOTE|NADH
|
84
|
|
fatty acid α-oxidation III
|
PWY66-388
|
4-trimethylaminobutyraldehyde dehydrogenase|fatty aldehyde dehydrogenase|2-hydroxyacyl-CoA lyase 1 [HACL1]4|sphingoliid fatty acid 2-hydroxylase|mitochondrial aldehyde dehydrogenase|long-chain-fatty-acid--CoA ligase 1|long-chain acyl-CoA synthetase 8 ACSBG2|2-hydroxyacyl-CoA lyase 1|very long-chain acyl-CoA synthetase
|
H2O|NAD+|diphosphate|phytosphingosine|a (2R)-2-hydroxy fatty acid|formyl-CoA|H+|formate|NADH|oxygen|coenzyme A
|
83
|
|
pentose phosphate pathway (non-oxidative branch)
|
NONOXIPENT-PWY
|
transaldolase|ribose-5-phosphate isomerase A|allose-6-phosphate isomerase / ribose-5-phosphate isomerase B|transketolase II|ribulose-5-phosphate 3-epimerase|transketolase I|transaldolase [TalB]2
|
D-ribulose 5-phosphate|D-xylulose 5-phosphate|D-erythrose 4-phosphate|β-D-fructofuranose 6-phosphate|D-sedoheptulose 7-phosphate|D-glyceraldehyde 3-phosphate
|
83
|
|
L-glutamate degradation VII (to butanoate)
|
GLUDEG-II-PWY
|
citramalate hydrolyase [component I][component II]|butyryl-CoA dehydrogenase|3-methylaspartase|glutamate mutase|phosphotransbutyrylase|3-hydroxybutyryl-CoA dehydratase|citramalate lyase, active form|pyruvate:ferredoxin oxidoreductase|acetyl-CoA acetyltransferase|3-hydroxybutyryl-CoA dehydrogenase|citramalate hydrolyase|butyrate kinase|crotonase|phosphotransbutyrylase [Ptb]8|butyrate kinase [Buk1]2
|
H2|(2S, 3S)-3-methylaspartate|(S)-3-hydroxybutanoyl-CoA|ammonium|butanoyl-CoA|crotonyl-CoA|H2O|NAD+|acetyl-CoA|butanoate|(S)-citramalate|L-glutamate|acetoacetyl-CoA|phosphate|pyruvate|CO2|acetate|butanoyl phosphate|coenzyme A|mesaconate|H+|NADH
|
83
|
|
TCA cycle II (plants and fungi)
|
PWY-5690
|
aconitase|malate dehydrogenase (NAD)|succinate dehydrogenase complex|fumarase|citrate synthase (mitochondrial)|succinyl-CoA synthetase|succinate dehydrogenase|NAD+-dependent isocitrate dehydrogenase|isocitrate dehydrogenase [NAD]|succinate dehydrogenase (ubiquinone)|malate dehydrogenase|citrate synthase
|
fumarate|H2O|NAD+|acetyl-CoA|2-oxoglutarate|(S)-malate|citrate|CO2|oxaloacetate|D-threo-isocitrate|H+|succinyl-CoA|phosphate|cis-aconitate|succinate|NADH|coenzyme A
|
83
|
|
L-lysine fermentation to acetate and butanoate
|
P163-PWY
|
3-aminobutyryl-CoA deaminase|L-3-aminobutyryl coenzyme A deaminase|butyryl-CoA:acetoacetate CoA-transferase|phosphotransacetylase|3-keto-5-aminohexanoate cleavage enzyme|L-β-lysine-5,6-aminomutase|3-keto,5-aminohexanoate cleavage enzyme|L-erythro-3,5-diaminohexanoate dehydrogenase|acetyl-CoA C-acetyltransferase|3,5-diaminohexanoate dehydrogenase|lysine 5,6-aminomutase|L-lysine 2,3-aminomutase|lysine 2,3-aminomutase
|
acetyl phosphate|acetate|(S)-5-amino-3-oxohexanoate|NAD+|acetyl-CoA|butanoate|acetoacetate|acetoacetyl-CoA|(S)-3-aminobutanoyl-CoA|H2O|L-β-lysine|(3S,5S)-3,5-diaminohexanoate|L-lysine|ammonium|H+|phosphate|butanoyl-CoA|NADH|crotonyl-CoA|coenzyme A
|
82
|
|
4-hydroxybenzoate biosynthesis V
|
PWY-6435
|
4-coumaroyl-CoA hydratase/aldolase couA|4-hydroxybenzoyl-CoA thioesterase [FcbC]4|4-coumarate coenzyme A ligase
|
H2O|NAD+|3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA|acetyl-CoA|4-hydroxybenzoate|diphosphate|4-hydroxybenzoyl-CoA|4-coumarate|4-hydroxybenzoyl-acetyl-CoA|4-coumaroyl-CoA|H+|NADH|coenzyme A
|
82
|
|
UDP-N-acetyl-D-galactosamine biosynthesis II
|
PWY-5514
|
glucose-6-phosphate isomerase|UDP-N-acetylglucosamine pyrophosphorylase|phosphoacetylglucosamine mutase|glucokinase|glucosamine 6-phosphate N-acetylase|glucosamine 6-phosphate isomerase 1
|
H2O|D-glucosamine 6-phosphate|N-acetyl-D-glucosamine 6-phosphate|acetyl-CoA|β-D-fructofuranose 6-phosphate|diphosphate|UDP-N-acetyl-α-D-galactosamine|N-acetyl-α-D-glucosamine 1-phosphate|UDP-N-acetyl-α-D-glucosamine|α-D-glucosamine 6-phosphate|H+|ammonium|D-glucopyranose 6-phosphate|coenzyme A
|
81
|