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heliocides biosynthesis
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PWY-5827
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(E)-β-ocimene|heliocide H4|hemigossypolone-6-methyl ether|hemigossypol-6-methyl ether|hemigossypol|heliocide B1|hemigossypolone|heliocide H3|heliocide H2|heliocide B4|heliocide H1|β-myrcene|heliocide B3|heliocide B2
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0
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heme biosynthesis III (from siroheme)
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PWY-7552
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heme synthase|siroheme decarboxylase|Fe-coproporphyrin synthase
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Fe-coproporphyrin III|L-methionine|acetate|siroheme|12,18-didecarboxysiroheme|ferroheme b|S-adenosyl-L-methionine|H+|CO2|5-deoxyadenosine
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0
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heme biosynthesis IV (Gram-positive bacteria)
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PWY-7766
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coproheme III oxidative decarboxylase|coproporphyrin ferrochelatase hemH|coproporphyrin ferrochelatase|coproporphyrinogen III oxidase (coproporphyrin-forming) hemY|uroporphyrinogen III decarboxylase|coproporphyrinogen III oxidase (coproporphyrin-forming)|coproheme III oxidative decarboxylase [HemQ]5
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Fe-coproporphyrin III|coproporphyrinogen III|uroporphyrinogen-III|coproporphyrin III|Fe2+|hydrogen peroxide|ferroheme b|H+|CO2|oxygen
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0
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heme d1 biosynthesis
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PWY-7554
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heme d1 dehydrogenase nirF|siroheme decarboxylase|pre-heme d1 synthase|heme d1 dehydrogenase
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S-adenosyl-L-methionine|L-methionine|H2O|ferroheme d1|pre-heme d1|siroheme|12,18-didecarboxysiroheme|H+|propanoate|CO2|5-deoxyadenosine
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0
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heme degradation
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PWY-5874
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heme oxygenase 1 HMOX1|biliverdin reductase A BLVRA|heme oxygenase 1|biliverdin reductase A
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H2O|carbon monoxide|Fe2+|ferroheme b|bilirubin|H+|biliverdin-IX-α|oxygen
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0
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hemoglobin degradation
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PWY-6423
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heme ligase|plasmepsin-2|falcilysin|heme ligase [HDP]2|plasmepsin-1 plasmepsin-1|plasmepsin 4|falcipain 2|histo-aspartic protease|falcipain-3|dipeptidyl aminopeptidase 1|plasmepsin-1|plasmepsin-2 plasmepsin-2
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H2O|hemozoin|β-hematin|a dipeptide|a large peptide (>20 AA)|a small peptide|ferriheme b
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0
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hentriaconta-3,6,9,12,15,19,22,25,28-nonaene biosynthesis
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PWY-7027
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OleA|hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase oleD|OleA oleA|hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase
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hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oate|H2O|16-hydroxy-hentriaconta-3,6,9,12,19,22,25,28-octaene-15-oyl-CoA|NADPH|hexadeca-4,7,10,13-tetraene-1-oyl-CoA|hentriaconta-3,6,9,12,15,19,22,25,28-nonaene|NADP+|hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one|hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA|H+|CO2|coenzyme A
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0
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heparan sulfate biosynthesis
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PWY-6564
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xylosylprotein 4-β-galactosyltransferase B4GALT7|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3|heparosan-N-sulfate-glucuronate 5-epimerase|[heparan sulfate]-glucosamine 3-O-sulfotransferase 1|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1|[heparan sulfate]-uronosyl-2-O-sulfotransferase 1|β-1,3-galactosyltransferase 6 B3GALT6|[heparan-sulfate]-6-O-sulfotransferase 1|[heparan sulfate]-glucosamine 3-O-sulfotransferase 2|galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase 2|xylosyltransferase 2|[heparan-sulfate]-6-O-sulfotransferase 3|xylosylprotein 4-β-galactosyltransferase|[heparan sulfate]-glucosamine 3-O-sulfotransferase 3A1|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2|exostosin complex [EXT2][EXT1]|heparosan-N-sulfate-glucuronate 5-epimerase GLCE|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4|[heparan-sulfate]-6-O-sulfotransferase 2|exostosin complex|N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase EXTL1|glucuronyl-galactosyl-proteoglycan 4-α-N-acetylglucosaminyltransferase 1|galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase 1|β-1,3-galactosyltransferase 6|galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase 3|[heparan sulfate]-glucosamine 3-O-sulfotransferase 3B1|xylosyltransferase 1
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UDP-N-acetyl-α-D-glucosamine|H2O|α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-core protein|α-N-acetyl-D-glucosaminyl-β-D-glucosyluronate-(1->3)-α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-core protein|a heparan-sulfate-β-D-glucuronate|acetate|3-phosphoadenylyl-sulfate|adenosine 3,5-bisphosphate|a core protein L-serine|β-D-glucosyluronate-(1->3)-α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-core protein|UDP-α-D-xylose|H+|a heparan sulfate-α-L-iduronate|UDP-α-D-galactose|UDP-α-D-glucuronate
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0
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heparan sulfate biosynthesis (late stages)
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PWY-6558
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[heparan-sulfate]-6-O-sulfotransferase 2|[heparan-sulfate]-6-O-sulfotransferase 1|exostosin complex|[heparan-sulfate]-6-O-sulfotransferase 3|N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase EXTL1|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2|exostosin complex [EXT2][EXT1]|heparosan-N-sulfate-glucuronate 5-epimerase|[heparan sulfate]-glucosamine 3-O-sulfotransferase 3A1|[heparan sulfate]-glucosamine 3-O-sulfotransferase 1|[heparan sulfate]-glucosamine 3-O-sulfotransferase 2|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1|[heparan sulfate]-uronosyl-2-O-sulfotransferase 1|heparosan-N-sulfate-glucuronate 5-epimerase GLCE|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4|glucuronyl-galactosyl-proteoglycan 4-α-N-acetylglucosaminyltransferase 1|[heparan sulfate]-glucosamine 3-O-sulfotransferase 3B1
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UDP-N-acetyl-α-D-glucosamine|H2O|α-N-acetyl-D-glucosaminyl-β-D-glucosyluronate-(1->3)-α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-core protein|a heparan-sulfate-β-D-glucuronate|acetate|3-phosphoadenylyl-sulfate|adenosine 3,5-bisphosphate|β-D-glucosyluronate-(1->3)-α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-core protein|UDP-α-D-glucuronate|H+|a heparan sulfate-α-L-iduronate|α-N-acetyl-D-glucosaminyl-(1->4)-β-D-glucosyluronate-(1->3)-β-D-galactosyl-(1->3)-β-D-galactosyl-(1->4)-β-D-xylosyl-core protein
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0
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heparan sulfate degradation
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PWY-7651
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unsaturated β-glucuronyl hydrolase|unsaturated β-glucuronyl hydrolase Phep_2830|heparinase II|N-sulfoglucosamine sulfohydrolase|heparinase III
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H2O|4-deoxy-L-threo-hex-4-enopyranuronate|sulfate|N-sulfo-D-glucosamine|4-deoxy-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine|D-glucosamine
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0
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