|
acetyl-CoA fermentation to butanoate II
|
PWY-5676
|
butyryl-CoA dehydrogenase|acetyl-CoA acetyltransferase|acetate CoA-transferase|acetate kinase|3-hydroxybutyryl-CoA dehydrogenase|phosphate acetyltransferase
|
acetyl phosphate|H2O|NADPH|acetyl-CoA|butanoate|acetoacetyl-CoA|NADP+|acetate|(3R)-3-hydroxybutanoyl-CoA|H+|phosphate|butanoyl-CoA|crotonyl-CoA|coenzyme A
|
105
|
|
purine nucleobases degradation II (anaerobic)
|
PWY-5497
|
xanthine amidohydrolase|pyruvate-ferredoxin oxidoreductase|2-iminobutanoate/2-iminopropanoate deaminase [RidA]3|phosphotransacetylase|xanthine dehydrogenase|L-serine ammonia-lyase|formimidoyltetrahydrofolate cyclodeaminase|4-ureido-5-imidazolecarboxylate amidohydrolase|4-imidazolonase|acetate kinase|4-aminoimidazolecarboxylate decarboxylase|glycine formimidoyltransferase [glycine formimidoyltransferase subunit]|NAD-dependent formate dehydrogenase|glycine formimidoyltransferase|serine hydroxymethyltransferase|methylenetetrahydrofolate dehydrogenase|methenyltetrahydrofolate cyclohydrolase|4-aminoimidazole deaminase|guanine deaminase
|
NADPH|4-amino-5-imidazole carboxylate|glycine|2-iminopropanoate|acetyl phosphate|hypoxanthine|a 5-formiminotetrahydrofolate|2-aminoprop-2-enoate|ammonium|a 5,10-methylene-tetrahydrofolate|6,8-dihydroxypurine|a 5,10-methenyltetrahydrofolate|H2O|NAD+|acetyl-CoA|a tetrahydrofolate|NADP+|8-hydroxypurine|phosphate|formate|pyruvate|CO2|acetate|L-serine|coenzyme A|urate|guanine|4-imidazolone|N-formimino-glycine|purine|4-aminoimidazole|4-ureido-5-imidazole carboxylate|an N10-formyl-tetrahydrofolate|H+|xanthine|NADH
|
105
|
|
superpathway of branched chain amino acid biosynthesis
|
BRANCHED-CHAIN-AA-SYN-PWY
|
threonine deaminase|branched-chain amino-acid aminotransferase|tyrosine aminotransferase|acetohydroxy acid isomeroreductase|acetolactate synthase / acetohydroxybutanoate synthase|2-iminobutanoate/2-iminopropanoate deaminase [RidA]3|D-malate / 3-isopropylmalate dehydrogenase (decarboxylating)|2-isopropylmalate synthase leuA|acetohydroxybutanoate synthase / acetolactate synthase|dihydroxy acid dehydratase|isopropylmalate isomerase|2-isopropylmalate synthase|3-isopropylmalate dehydrogenase
|
NADPH|(R)-2,3-dihydroxy-3-methylpentanoate|2-isopropylmaleate|ammonium|(2S)-2-isopropyl-3-oxosuccinate|(S)-3-methyl-2-oxopentanoate|(2R)-2,3-dihydroxy-3-methylbutanoate|H2O|NAD+|acetyl-CoA|NADP+|L-glutamate|L-valine|4-methyl-2-oxopentanoate|pyruvate|CO2|(2R,3S)-3-isopropylmalate|L-leucine|L-threonine|(2Z)-2-aminobut-2-enoate|coenzyme A|3-methyl-2-oxobutanoate|L-isoleucine|2-iminobutanoate|(S)-2-aceto-2-hydroxybutanoate|(S)-2-acetolactate|2-oxobutanoate|(2S)-2-isopropylmalate|H+|2-oxoglutarate|NADH
|
105
|
|
L-citrulline biosynthesis
|
CITRULBIO-PWY
|
mitochondrial proline dehydrogenase 1|ornithine carbamoyltransferase|glutaminase, liver isoform|δ-1-pyrroline-5-carboxylate synthase|glutaminase, kidney isoform|arginase 2|arginase 1|ornithine aminotransferase
|
carbamoyl phosphate|H2O|(S)-1-pyrroline-5-carboxylate|NADPH|ammonium|urea|L-glutamine|γ-L-glutamyl 5-phosphate|NADP+|L-proline|L-glutamate-5-semialdehyde|L-arginine|L-ornithine|L-glutamate|L-citrulline|H+|phosphate|2-oxoglutarate
|
105
|
|
chorismate biosynthesis I
|
ARO-PWY
|
shikimate kinase|shikimate kinase II|shikimate dehydrogenase / quinate dehydrogenase|chorismate synthase|3-dehydroquinate dehydratase|shikimate 5-dehydrogenase|shikimate dehydrogenase / quinate dehydrogenase [YdiB]2|3-phosphoshikimate-1-carboxyvinyltransferase|3-dehydroquinate synthase|pentafunctional AROM polypeptide|shikimate dehydrogenase|chorismate mutase / DAHP synthase|2-dehydro-3-deoxyphosphoheptonate aldolase|5-enolpyruvoylshikimate-3-phosphate synthase
|
H2O|NADPH|3-deoxy-D-arabino-heptulosonate 7-phosphate|shikimate|NADP+|phosphoenolpyruvate|3-dehydroshikimate|chorismate|shikimate 3-phosphate|3-dehydroquinate|H+|D-erythrose 4-phosphate|phosphate|5-enolpyruvoyl-shikimate 3-phosphate
|
104
|
|
superpathway of tetrahydrofolate biosynthesis and salvage
|
FOLSYN-PWY
|
phosphoribosylglycinamide formyltransferase 1|GTP cyclohydrolase I|dihydromonapterin reductase / dihydrofolate reductase|bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase|aminodeoxychorismate lyase, subunit of para-aminobenzoate synthase multi-enzyme complex|dihydroneopterin triphosphate pyrophosphohydrolase|4-amino-4-deoxychorismate synthase, subunit of para-aminobenzoate synthase multi-enzyme complex|dihydrofolate reductase|6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase|dihydropteroate synthase|dihydroneopterin aldolase|bifunctional folylpolyglutamate synthetase / dihydrofolate synthetase
|
NADPH|L-glutamine|4-amino-4-deoxychorismate|chorismate|(7,8-dihydropterin-6-yl)methyl diphosphate|7,8-dihydroneopterin|a 7,8-dihydrofolate|a 5,10-methenyltetrahydrofolate|H2O|NADP+|7,8-dihydroneopterin 3-phosphate|L-glutamate|7,8-dihydroneopterin 3-triphosphate|phosphate|formate|pyruvate|7,8-dihydropteroate|glycolaldehyde|a tetrahydrofolate|7,8-dihydrofolate monoglutamate|diphosphate|4-aminobenzoate|an N10-formyl-tetrahydrofolate|H+|6-(hydroxymethyl)-7,8-dihydropterin
|
104
|
|
flavin biosynthesis I (bacteria and plants)
|
RIBOSYN2-PWY
|
riboflavin synthase, subunit of riboflavin synthase/6,7-dimethyl-8-ribityllumazine synthase complex|chloroplastic riboflavin biosynthesis protein ribBA|5-amino-6-(5-phosphoribosylamino)uracil reductase|3,4-dihydroxy-2-butanone 4-phosphate synthase|6,7-dimethyl-8-ribityllumazine synthase|6,7-dimethyl-8-ribityllumazine synthase, subunit of riboflavin synthase/6,7-dimethyl-8-ribityllumazine synthase complex|diaminohydroxyphosphoribosylaminopyrimidine deaminase|bifunctional riboflavin kinase / FMN adenylyltransferase|FMN adenylyltransferase / riboflavin kinase|5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase|GTP cyclohydrolase II|riboflavin synthase|fused diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase|chloroplastic 6,7-dimethyl-8-ribityllumazine synthase
|
D-ribulose 5-phosphate|H2O|6,7-dimethyl-8-(1-D-ribityl)lumazine|NADPH|FAD|ammonium|5-amino-6-(D-ribitylamino)uracil|diphosphate|NADP+|riboflavin|1-deoxy-L-glycero-tetrulose 4-phosphate|H+|phosphate|formate
|
104
|
|
superpathway NAD/NADP - NADH/NADPH interconversion (yeast)
|
PWY-7245
|
aldehyde dehydrogenase, mitochondrial|NADH:ubiquinone oxidoreductase 1 (external)|magnesium-activated aldehyde dehydrogenase, cytosolic|NADH:ubiquinone oxidoreductase (internal)|glucose-6-phosphate dehydrogenase|potassium-activated aldehyde dehydrogenase, mitochondrial|NADH:ubiquinone oxidoreductase 2 (external)|NAD(+)/NADH kinase|NADP-dependent isocitrate dehydrogenase
|
6-phospho D-glucono-1,5-lactone|acetate|NADPH|D-glucopyranose 6-phosphate|NADP+|H2O|CO2|D-threo-isocitrate|H+|NAD+|acetaldehyde|2-oxoglutarate|NADH|a carboxylate
|
103
|
|
pyrimidine deoxyribonucleotide phosphorylation
|
PWY-7197
|
|
dTMP kinase|nucleoside diphosphate kinase|cytidylate kinase|thymidylate kinase|nucleoside-diphosphate kinase|UMP/CMP kinase|nucleoside-diphosphate kinase 1
|
103
|
|
superpathway of sulfate assimilation and cysteine biosynthesis
|
SULFATE-CYS-PWY
|
O-acetylserine sulfhydrylase A, subunit of cysteine synthase complex|sulfate adenylyltransferase|3-phosphoserine aminotransferase [multifunctional]|cysteine synthase B|phosphoserine phosphatase|adenylylsulfate kinase|assimilatory sulfite reductase (NADPH)|2-oxoglutarate reductase ((S)-2-hydroxyglutarate-forming) [multifunctional]|serine acetyltransferase, subunit of cysteine synthase complex
|
NADPH|sulfate|3-phosphoadenylyl-sulfate|L-cysteine|H2O|NAD+|acetyl-CoA|3-phospho-hydroxypyruvate|NADP+|adenosine 3,5-bisphosphate|sulfite|L-glutamate|phosphate|acetate|L-serine|3-phospho-L-serine|adenosine 5-phosphosulfate|coenzyme A|hydrogen sulfide|O-acetyl-L-serine|3-phospho-D-glycerate|diphosphate|H+|2-oxoglutarate|NADH
|
102
|