|
glycolysis V (Pyrococcus)
|
P341-PWY
|
2,3-bisphosphoglycerate-independent phosphoglycerate mutase|pyruvate kinase|ADP-dependent glucokinase|ADP-dependent phosphofructokinase [PfkA]4|glyceraldehyde-3-phosphate ferredoxin oxidoreductase gor|ADP-dependent phosphofructokinase|fructose-1,6-bisphosphate aldolase|glyceraldehyde-3-phosphate ferredoxin oxidoreductase|enolase|triose phosphate isomerase|phosphoglucose isomerase
|
H2O|3-phospho-D-glycerate|D-glucopyranose 6-phosphate|2-phospho-D-glycerate|fructose 1,6-bisphosphate|phosphoenolpyruvate|glycerone phosphate|β-D-fructofuranose 6-phosphate|D-glyceraldehyde 3-phosphate|H+|pyruvate
|
108
|
|
L-homoserine and L-methionine biosynthesis
|
METSYN-PWY
|
O-succinylhomoserine(thiol)-lyase / O-succinylhomoserine lyase [MetB]4|homoserine O-succinyltransferase [MetA]2
|
L-cysteine|2-aminoprop-2-enoate|NADPH|N5-methyl--tetrahydropteroyl tri-L-glutamate|L-methionine|tetrahydropteroyl tri-L-glutamate|a tetrahydrofolate|L-aspartyl-4-phosphate|L-homocysteine|NADP+|an N5-methyl-tetrahydrofolate|L-aspartate|O-succinyl-L-homoserine|L-aspartate-semialdehyde|L-homoserine|H+|succinyl-CoA|phosphate|succinate|L-cystathionine|coenzyme A
|
108
|
|
TCA cycle IV (2-oxoglutarate decarboxylase)
|
P105-PWY
|
malate synthase|succinate dehydrogenase sdhA|succinate-semialdehyde dehydrogenase|2-oxoglutarate decarboxylase|fumarase
|
fumarate|H2O|NADPH|acetyl-CoA|succinate semialdehyde|2-oxoglutarate|(S)-malate|citrate|NADP+|glyoxylate|CO2|oxaloacetate|D-threo-isocitrate|H+|NAD+|cis-aconitate|succinate|NADH|coenzyme A
|
108
|
|
folate transformations I
|
PWY-2201
|
ferredoxin-dependent methylenetetrahydrofolate reductase|5,10-methenyltetrahydrofolate synthetase|formyltetrahydrofolate deformylase|methenyl tetrahydrofolate cyclohydrolase|formate-tetrahydrofolate ligase|methenyltetrahydrofolate cyclohydrolase [multifunctional]|NADP-dependent methylene tetrahydromethanopterin dehydrogenase [multifunctional]|glycine cleavage system|methylene tetrahydrofolate reductase|bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase|serine hydroxymethyltransferase|5,10-methylenetetrahydrofolate reductase|cobalamin-dependent methionine synthase|methenyl tetrahydrofolate cyclohydrolase [multifunctional]|formyltetrahydrofolate synthetase|ferredoxin-dependent methylenetetrahydrofolate reductase [methylenetetrahydrofolate reductase (ferredoxin) α subunit]4[methylenetetrahydrofolate reductase (ferredoxin) β subunit]4|trimethylsulfonium-tetrahydrofolate methyltransferase|5-formyltetrahydrofolate cyclo-ligase
|
NADPH|glycine|ammonium|a 5,10-methylene-tetrahydrofolate|a 5,10-methenyltetrahydrofolate|L-methionine|H2O|NAD+|L-homocysteine|NADP+|phosphate|formate|CO2|dimethyl sulfide|L-serine|a tetrahydrofolate|an N5-methyl-tetrahydrofolate|an (6S)-N5-formyl-tetrahydrofolate|trimethyl sulfonium|an N10-formyl-tetrahydrofolate|H+|NADH
|
108
|
|
TCA cycle I (prokaryotic)
|
TCA
|
isocitrate dehydrogenase|succinate:quinone oxidoreductase|isocitrate dehydrogenase (NADP-dependent)|malate dehydrogenase|fumarase B|malate:quinone oxidoreductase|aconitate hydratase 1|2-oxoglutarate dehydrogenase complex|fumarase A|fumarase C|succinyl-CoA synthetase|malate:quinone oxidoreductase mqo|bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase|citrate synthase
|
fumarate|H2O|NADPH|phosphate|acetyl-CoA|2-oxoglutarate|(S)-malate|citrate|NADP+|CO2|oxaloacetate|D-threo-isocitrate|H+|succinyl-CoA|NAD+|cis-aconitate|succinate|NADH|coenzyme A
|
107
|
|
superpathay of heme biosynthesis from glutamate
|
PWY-5918
|
glutamyl-tRNA synthetase|uroporphyrinogen III synthase|glutamyl-tRNA reductase|glutamate-1-semialdehyde aminotransferase|uroporphyrinogen III cosynthetase|uroporphyrinogen decarboxylase|coproporphyrinogen III oxidase|glutamate-1-semialdehyde 2,1-aminomutase|porphobilinogen deaminase|hydroxymethylbilane synthase|porphobilinogen synthase|protoporphyrinogen IX oxidase isozyme II|ferrochelatase|protoporphyrinogen oxidase
|
coproporphyrinogen III|H2O|NADPH|porphobilinogen|protoporphyrinogen IX|(S)-4-amino-5-oxopentanoate|Fe2+|uroporphyrinogen-III|NADP+|diphosphate|ferroheme b|L-glutamate|preuroporphyrinogen|hydrogen peroxide|H+|ammonium|protoporphyrin IX|5-aminolevulinate|CO2|oxygen
|
107
|
|
superpathway of phospholipid biosynthesis II (plants)
|
PHOSLIPSYN2-PWY
|
phosphatidylglycerolphosphate synthase|phosphatidyl-N-dimethylethanolamine N-methyltransferase|phosphatidylserine synthase 2 PTDSS2|lysophosphatidate acyltransferase|phosphatidylglycerolphosphate phosphatase|serine decarboxylase|glycerol-3-phosphate O-acyltransferase|phosphatidylinositol synthase|cholinephosphate cytidylyltransferase|N-dimethylphosphoethanolamine cytidylyltransferase|cytoplasmic glycerol-3-phosphate acyltransferase|phosphatidylserine decarboxylase|CDP-diacylglycerol synthase|N-methylphosphoethanolamine cytidylyltransferase|phosphatidate cytidylyltransferase / phytol kinase|phosphatidyl-N-methylethanolamine N-methyltransferase|phosphatidylserine synthase|aminoalcoholphosphotransferase|CDP-ethanolamine synthase|chloroplastidic glycerol-3-phosphate O-acyltransferase|choline kinase|ethanolamine kinase|CDP-choline:1,2-diacylglycerol cholinephosphotransferase|ethanolamine-phosphate cytidylyltransferase|phosphoethanolamine N-methyltransferase
|
S-adenosyl-L-methionine|phosphocholine|a CDP-diacylglycerol|ethanolamine|an L-1-phosphatidylserine|CO2|myo-inositol|O-phosphoethanolamine|H2O|a 1,2-diacyl-sn-glycerol|N-methylethanolamine phosphate|sn-glycerol 3-phosphate|phosphate|CDP-N-methylethanolamine|S-adenosyl-L-homocysteine|CDP-N-dimethylethanolamine|N-dimethylethanolamine phosphate|L-serine|choline|a 1-acyl-sn-glycerol 3-phosphate|a phosphatidyl-N-dimethylethanolamine|1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate|coenzyme A|CDP-ethanolamine|diphosphate|glycerone phosphate|a phosphatidyl-N-methylethanolamine|H+
|
107
|
|
L-lysine biosynthesis VI
|
PWY-5097
|
aspartate semialdehyde dehydrogenase|diaminopimelate epimerase|L,L-diaminopimelate aminotransferase|4-hydroxy-tetrahydrodipicolinate synthase|4-hydroxy-tetrahydrodipicolinate reductase|diaminopimelate decarboxylase|aspartate kinase
|
H2O|NADPH|meso-diaminopimelate|2-oxoglutarate|L-aspartyl-4-phosphate|NADP+|L-aspartate|L-lysine|L-glutamate|L,L-diaminopimelate|H+|L-aspartate-semialdehyde|phosphate|pyruvate|CO2|(S)-2,3,4,5-tetrahydrodipicolinate|(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
|
106
|
|
superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)
|
PWY-5910
|
diphosphomevalonate decarboxylase|farnesyltranstransferase|geranylgeranyl diphosphate synthase|isopentenyl diphosphate isomerase|mevalonate diphosphate decarboxylase|isopentenyl-diphosphate delta-isomerase 2|phosphomevalonate kinase|mevalonate kinase|HMG-CoA reductase 1|geranylpyrophosphate synthase|acetoacetyl-CoA thiolase|ω,E,E-farnesyl diphosphate synthase / dimethylallyltranstransferase|acetyl-CoA C-acetyltransferase|3-hydroxy-3-methylglutaryl coenzyme A reductase|E-farnesyl diphosphate synthase|isopentenyl-diphosphate delta-isomerase 1|hydroxymethylglutaryl-CoA synthase|mitochondrial acetyl-CoA acetyltransferase|3-hydroxy-3-methylglutaryl-coenzyme A reductase|farnesyl diphosphate synthase|hydroxymethylglutaryl CoA synthase|geranylgeranyltransferase type I [FTA][GGB]|mitochondrial hydroxymethylglutaryl-CoA synthase|HMG-CoA reductase 2|IPP isomerase|cytosolic acetyl-CoA acetyltransferase|ω,E,E-farnesyl diphosphate synthase|geranylgeranyl pyrophosphate synthase
|
H2O|NADPH|dimethylallyl diphosphate|acetyl-CoA|diphosphate|acetoacetyl-CoA|(S)-3-hydroxy-3-methylglutaryl-CoA|NADP+|isopentenyl diphosphate|geranylgeranyl diphosphate|(R)-mevalonate diphosphate|geranyl diphosphate|H+|(R)-mevalonate 5-phosphate|phosphate|(R)-mevalonate|CO2|(2E,6E)-farnesyl diphosphate|coenzyme A
|
106
|
|
superpathway of guanosine nucleotides de novo biosynthesis I
|
PWY-7228
|
GMP synthase|nucleoside diphosphate kinase|ribonucleoside diphosphate reductase 1|guanylate kinase|GMP synthetase|IMP dehydrogenase|ribonucleoside-diphosphate reductase|nucleoside-diphosphate kinase 1
|
H2O|NAD+|L-glutamine|diphosphate|L-glutamate|H+|NADH
|
105
|