superpathway of mycolate biosynthesis
|
PWY-6113
|
Rv3802c lipase/thioesterase|antigen 85C|accD6|mycolyl-trehalose-6-phosphate phosphatase|methoxy mycolic acid synthase 3 mmaA3|meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II|methoxy mycolic acid synthase 2|methoxymycolic acid synthase 4|methoxy mycolic acid synthase 3|meromycolic acid enoyl-[acyl-carrier-protein] reductase|methoxy mycolic acid synthase 1|Pks13|meromycolic acid 3-hydroxyacyl-[acyl-carrier-protein] dehydratase I [HadA][HadB]|lpqX|meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I|Rv2509 Rv2509|methoxy mycolic acid synthase 1 mmaA1|drugs-transport transmembrane ATP-binding protein ABC transporter Rv1273c|meromycolic acid 3-hydroxyacyl-[acyl-carrier-protein] dehydratase I|meromycolic acid 3-hydroxyacyl-[acyl-carrier-protein] dehydratase II|acyl-CoA synthetase|Pks13 pks13|meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I kasA|2-trans-enoyl-ACP isomerase|meromycolic acid 3-oxoacyl-[acyl-carrier-protein] reductase|Rv2509|meromycolic acid 3-hydroxyacyl-[acyl-carrier-protein] dehydratase II [HadB][HadC]|fatty acid synthase [FASN]2|meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II kasB|acetyl/propionyl-CoA carboxylase alpha chain|antigen 85B|cyclopropane synthase|propionyl-CoA carboxylase beta chain 4|propionyl-coa carboxylase beta chain 5|cyclopropane mycolic acid synthase 2|methoxymycolic acid synthase 4 mmaA4|fatty acid synthase|fatty acid synthase fas|methoxy mycolic acid synthase 2 mmaA2|cyclopropane mycolic acid synthase 2 cmaA2|antigen 85A|acyl-carrier-protein S-malonyltransferase|meromycolic acid 3-oxoacyl-[acyl-carrier-protein] reductase [FabG1]2|acyl-CoA synthetase fadD32|trans-delta20-39-hydroxy-40-methyl-C60:1-[acp] oxidoreductase [multifunctional] Rv0161|trehalose-6-phosphate phosphatase OtsB1|trans-delta20-39-hydroxy-40-methyl-C60:1-[acp] oxidoreductase [multifunctional]|meromycolic acid enoyl-[acyl-carrier-protein] reductase [InhA]4
|
S-adenosyl-L-methionine|lauroyl-CoA|6-O-trans-methoxy-mycolyl-trehalose 6-phosphate|NADPH|2-carboxy-cerotoyl-CoA|a trans-keto-meroacyl-adenylate|6-O-trans-keto-mycolyl-β-D-mannopyranosyl-1-phosphoheptaprenol|6-O-mycolyl-trehalose 6-phosphate|hydrogen carbonate|a cis-keto-meroacyl-adenylate|arabinogalactan-cis-methoxy-mycolate|stearate|6-O-mycolyl-β-D-mannopyranosyl-1-phosphoheptaprenol|α,α-trehalose 6-phosphate|laurate|H2O|NAD+|acetyl-CoA|cerotoyl-CoA|a C52-α-meroacyl-adenylate|stearoyl-CoA|NADP+|6-O-trans-methoxy-mycolyl-β-D-mannopyranosyl-1-phosphoheptaprenol|trehalose-cis-keto-di-mycolate|6-O-cis-keto-mycolyl-trehalose 6-phosphate|arabinogalactan-cis-keto-mycolate|a trans-methoxy-meroacyl-adenylate|phosphate|D-mannopyranosyl-1-phosphoheptaprenol|CO2|trehalose-trans-methoxy-di-mycolate|trehalose-trans-keto-di-mycolate|6-O-trans-keto-mycolyl-trehalose 6-phosphate|arabinogalactan-trans-methoxy-mycolate|6-O-cis-methoxy-mycolyl-β-D-mannopyranosyl-1-phosphoheptaprenol|6-O-cis-methoxy-mycolyl-trehalose 6-phosphate|palmitate|mycolyl-arabinogalactan-peptidoglycan complex|malonyl-CoA|trehalose-cis-keto-mono-mycolate|trehalose-trans-methoxy-mono-mycolate|coenzyme A|trehalose-cis-methoxy-di-mycolate|a cis-methoxy-meroacyl-adenylate|trehalose-trans-keto-mono-mycolate|palmitoyl-CoA|trehalose-cis-methoxy-mono-mycolate|diphosphate|6-O-cis-keto-mycolyl-β-D-mannopyranosyl-1-phosphoheptaprenol|α,α-trehalose|S-adenosyl-L-homocysteine|α, α-trehalose 6,6-bismycolate|arabinogalactan-trans-keto-mycolate|H+|NADH
|
711
|
superpathway of fatty acids biosynthesis (E. coli)
|
PWY-6285
|
enoyl-[acyl-carrier-protein] reductase [FabI]4|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase [FabZ]6|fatty acyl-CoA synthetase|short chain acyl-CoA synthetase|KASI [FabB]2|KASIII|multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 [TesA]4|3-oxoacyl-[acyl-carrier-protein] reductase [FabG]4|acetyl-CoA carboxylase|KASI|fatty acid synthase [FASN]2|β-hydroxyacyl-ACP dehydratase/isomerase|KASII [FabF]2|KASII|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase|malonyl-CoA-ACP transacylase|3-oxoacyl-[acyl-carrier-protein] reductase|multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1|enoyl-[acyl-carrier-protein] reductase
|
lauroyl-CoA|H2O|malonyl-CoA|NADPH|phosphate|acetyl-CoA|hydrogen carbonate|cis-vaccenate|diphosphate|palmitoleate|NADP+|NADH|palmitoyl-CoA|H+|NAD+|CO2|coenzyme A|laurate|palmitate
|
704
|
superpathway of fatty acid biosynthesis II (plant)
|
PWY-5156
|
3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic|enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic|3-ketoacyl-[acp] synthase 2, chloroplastic|malonyl-CoA:ACP transacylase|β-ketoacyl-[acp] synthase III|fatty acid synthase [FASN]2|long-chain acyl-CoA synthetase 3|long-chain acyl-CoA synthetase 9|3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic|long-chain acyl-CoA synthetase 7|[acyl-carrier protein] S-malonyltransferase|acetyl-CoA carboxylase|long-chain acyl-CoA synthetase 6|stearoyl-[acp] 9-desaturase
|
lauroyl-CoA|NADPH|NADP+|stearate|laurate|H2O|NAD+|acetyl-CoA|stearoyl-CoA|hydrogen carbonate|phosphate|CO2|oleoyl-CoA|palmitate|malonyl-CoA|oxygen|coenzyme A|palmitoyl-CoA|diphosphate|oleate|H+|NADH
|
696
|
superpathway of fatty acid biosynthesis I (E. coli)
|
PWY0-881
|
enoyl-[acyl-carrier-protein] reductase [FabI]4|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase [FabZ]6|KASI [FabB]2|KASII|3-oxoacyl-[acyl-carrier-protein] reductase [FabG]4|KASIII|KASI|β-hydroxyacyl-ACP dehydratase/isomerase|acetyl-CoA carboxylase|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase|malonyl-CoA-ACP transacylase|3-oxoacyl-[acyl-carrier-protein] reductase|enoyl-[acyl-carrier-protein] reductase
|
H2O|NAD+|phosphate|acetyl-CoA|hydrogen carbonate|NADP+|CO2|H+|NADPH|malonyl-CoA|NADH|coenzyme A
|
651
|
tRNA charging
|
TRNA-CHARGING-PWY
|
isoleucyl-tRNA synthetase ileS|cysteinyl-tRNA synthetase|methionyl-tRNA synthetase|isoleucyl-tRNA synthetase|valyl-tRNA synthetase|valyl-tRNA synthetase valS|prolyl-tRNA synthetase|lysyl-tRNA synthetase, constitutive|alanyl-tRNA synthetase and DNA-binding transcriptional repressor [AlaS]2|tyrosyl-tRNA synthetase [TyrS]2|alanyl-tRNA synthetase and DNA-binding transcriptional repressor|prolyl-tRNA synthetase [ProS]2|histidyl-tRNA synthetase [HisS]2|tyrosyl-tRNA synthetase|aspartyl-tRNA synthetase|Ap3A synthetase / Ap4A synthetase / lysyl-tRNA synthetase|seryl-tRNA synthetase|arginyl-tRNA synthetase|leucyl-tRNA synthetase leuS|glutamyl-tRNA synthetase|glycyl-tRNA synthetase [GlyS]2[GlyQ]2|threonyl-tRNA synthetase|methionyl-tRNA synthetase [MetG]2|glutaminyl-tRNA synthetase|arginyl-tRNA synthetase argS|glycyl-tRNA synthetase|leucyl-tRNA synthetase|asparaginyl-tRNA synthetase|tryptophanyl-tRNA synthetase|cysteinyl-tRNA synthetase cysS|tryptophanyl-tRNA synthetase [TrpS]2|histidyl-tRNA synthetase|phenylalanyl-tRNA synthetase [PheS]2[PheT]2|threonyl-tRNA synthetase [ThrS]2|phenylalanyl-tRNA synthetase
|
glycine|L-histidine|L-glutamine|L-cysteine|L-alanine|L-glutamate|L-tryptophan|L-valine|L-phenylalanine|L-asparagine|L-serine|L-tyrosine|L-methionine|L-leucine|L-proline|L-lysine|L-arginine|L-threonine|L-isoleucine|diphosphate|L-aspartate|H+
|
631
|
octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)
|
PWY-7388
|
Acetyl-CoA carboxylase, mitochondrial|malonyl-CoA:ACP transferase|2-enoyl thioester reductase|hydroxyacyl-thioester dehydratase|3-oxoacyl-[acyl-carrier-protein] reductase|beta-keto-acyl synthase homolog
|
H2O|NADPH|acetyl-CoA|NADP+|hydrogen carbonate|H+|phosphate|malonyl-CoA|CO2|coenzyme A
|
627
|
superpathway of histidine, purine, and pyrimidine biosynthesis
|
PRPP-PWY
|
amidophosphoribosyl transferase|phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase|phosphoribosylformylglycinamide cyclo-ligase|IMP dehydrogenase|dihydroorotate dehydrogenase, type 2|orotate phosphoribosyltransferase|histidinol-phosphate aminotransferase|imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase|ribose 1,5-bisphosphokinase|phosphoribosylaminoimidazole-succinocarboxamide synthase|nucleoside diphosphate kinase|ribonucleoside-diphosphate reductase 2|dihydroorotase|carbamoyl phosphate synthetase|N5-carboxyaminoimidazole ribonucleotide synthetase|phosphopentomutase|AICAR transformylase / IMP cyclohydrolase|ribose-phosphate diphosphokinase|dihydroorotate dehydrogenase, type 2 pyrD|CTP synthase|ribonucleoside-triphosphate reductase, subunit of anaerobic nucleoside-triphosphate reductase activating system|N5-carboxyaminoimidazole ribonucleotide synthetase [PurK]2|guanylate kinase|imidazole glycerol phosphate synthase|histidinal dehydrogenase / histidinol dehydrogenase|N5-carboxyaminoimidazole ribonucleotide mutase|adenylate kinase|adenylosuccinate lyase|N5-carboxyaminoimidazole ribonucleotide mutase [PurE]8|UMP kinase|ribonucleoside-triphosphate reductase [NrdD]2|ribose 1,5-bisphosphokinase phnN|GMP synthetase|phosphoribosylformylglycinamide synthetase|ribonucleoside diphosphate reductase 1|aspartate transcarbamylase|phosphoribosylamine-glycine ligase|adenylosuccinate synthetase|ATP phosphoribosyltransferase
|
fumarate|glycine|L-histidine|L-glutamine|adenylo-succinate|α-D-ribose-1-phosphate|orotate|(S)-dihydroorotate|N5-carboxyaminoimidazole ribonucleotide|1-(5-phospho-β-D-ribosyl)-ATP|histidinal|H2O|NAD+|hydrogen carbonate|L-histidinol-phosphate|N-carbamoyl-L-aspartate|L-glutamate|imidazole acetol-phosphate|phosphate|5-phospho-α-D-ribose 1-diphosphate|formate|CO2|orotidine 5-phosphate|histidinol|a tetrahydrofolate|α-D-ribose 1,5-bisphosphate|an N10-formyl-tetrahydrofolate|carbamoyl phosphate|5-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole|diphosphate|L-aspartate|D-erythro-imidazole-glycerol-phosphate|H+|5-phospho-β-D-ribosylamine|2-oxoglutarate|NADH
|
601
|
palmitate biosynthesis II (bacteria and plants)
|
PWY-5971
|
3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic|enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase|enoyl-[acyl-carrier-protein] reductase|short chain acyl-CoA synthetase|KASI|fatty acyl-CoA synthetase|fatty acid synthase [FASN]2|long-chain acyl-CoA synthetase 9|3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic|3-hydroxyacyl-[acp] dehydrase|3-oxoacyl-[acyl-carrier-protein] reductase
|
lauroyl-CoA|H2O|NADPH|palmitoyl-CoA|diphosphate|NADP+|NADH|H+|NAD+|CO2|coenzyme A|laurate|palmitate
|
584
|
palmitate biosynthesis I (animals and fungi)
|
PWY-5994
|
fatty acid synthase, β subunit|fatty acid synthase|acyl-CoA thioesterase 2 (mitochondrial)|fatty acid synthase, α subunit|fatty acid synthase [FASN]2|fatty acid synthase, β subunit FAS1|acyl-CoA thioesterase 1, cytosolic|2-enoyl thioester reductase|hydroxyacyl-thioester dehydratase|3-oxoacyl-[acyl-carrier-protein] reductase|acyl-CoA thioesterase 4, proxisomal
|
H2O|NADPH|palmitoyl-CoA|NADP+|CO2|H+|palmitate|malonyl-CoA|laurate|coenzyme A
|
565
|
superpathway of unsaturated fatty acids biosynthesis (E. coli)
|
PWY-6284
|
enoyl-[acyl-carrier-protein] reductase [FabI]4|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase [FabZ]6|KASI [FabB]2|KASI|multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 [TesA]4|3-oxoacyl-[acyl-carrier-protein] reductase [FabG]4|3-oxoacyl-[acyl-carrier-protein] reductase|KASII|β-hydroxyacyl-ACP dehydratase/isomerase|KASII [FabF]2|3-hydroxy-acyl-[acyl-carrier-protein] dehydratase|enoyl-[acyl-carrier-protein] reductase|multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1
|
H2O|NAD+|palmitoleate|NADP+|CO2|H+|NADPH|cis-vaccenate|NADH
|
551
|